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Tag Content
UUCD2 ID IUUC-Fca-035947
UUCD1 version UUC-FeC-00781
Ensembl Protein ID ENSFCAP00000006645.3
UniProt Accession M3W789; M3W789_FELCA
Genbank Protein ID ENSFCAP00000006645
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID AANG02194591
Gene Name USP45
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSFCAG00000007166.3 ENSFCAT00000007168.3 ENSFCAP00000006645.3
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 7.30e-86 288.4 159 780
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenp..............kepkgellkslqklfeelwkskkkavsprellk 75
           +G++NlgNtC++N+v+Q L++   l el++e+k++ ++ +                 ++ g+l+++l  +++++ +++k+  sp+ l++
   Q: 159  KGITNLGNTCFFNAVMQNLAQSYILSELMNESKENGTKLK-IfpssdshldplmveLSSPGPLTSALFLFLHSMKETEKGPLSPKVLFN 246
           59*****************************444444433.24566667777777788888**************************** PP
   S: 76   alkkeaeefsgyeqqDaqEflaflldqleeelkk........eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikc 156
           +l+++a++f+g++qqD+qE+l++lld++++e +k          n+p++++ ++d++++s+  ++  +  + ++i+++F g+l+s+++c
   Q: 247  QLCQKAPRFKGFQQQDSQELLHYLLDAVRTEETKriqagilkAFNNPTTKTADDDTKKRSK-XSYGREGVKMNFIDRIFIGELTSTVMC 334
           ********************************99455555544444444444444333332.4555666666***************** PP
   S: 157  lecdnvssreepfldlslpvpgkeetkke............................................................ 185
           +ec+n+s+ ++pf+d+slp+ +++ +k+                                                             
   Q: 335  EECANISTVKDPFIDISLPIIEERVSKPVllgrmnkcrslqatdtgqysdtvtienvqqpratknqssskdknqlvhgrkcvrklpsge 423
           ************************98777************************************************************ PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 424  drvavicreyenpgmsgdssvcagvvsteaalaesptdgsekeaspsessadadseasesestsqqavllrsrsgccahkngpppqrpl 512
           ***************************************************************************************** PP
   S: 186  ..........................................................................slqdcLesftkeeel 200
                                                                                     s+q+cL +ft+ e l
   Q: 513  tketgsgdegvaeaiselylsstvtgdgdldrenkppdipnnlcssqekyvlspspqkaflslsqsyittskecSVQSCLYQFTSMELL 601
           ***************************************************************************************** PP
   S: 201  egenkyycekckkkqe...................aekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspee 270
            g+nk+ ce+c++k++                   a+k+l ++ +P  LilhLkRf  ++++ + +k+n++v+fpl Ldl+pfc+ +++
   Q: 602  MGNNKLLCENCTEKKQkyqketisaekkaegvytnARKQLLISAIPANLILHLKRF--HQAGLNLRKVNRHVDFPLILDLAPFCSATCK 688
           ************99999999999999999999999*********************..99999***********************999 PP
   S: 271  kqke..kkkYeLiavvvHsGslssGHYvayvkn..........................ekgkWllfdDskVtevkeeevleetgstaY 331
           ++++  k+ Y L++vv HsGs+++GHY+ayvk                           + ++W++++D++V++v+e++ l+   ++aY
   Q: 689  NVNVgdKVLYGLYGVVEHSGSMRGGHYTAYVKVrapsrkllehitgkknvpdlkepdseSADQWVHVSDTYVQVVPESRALS---AQAY 774
           98878899*************************999999999999999999998888766777*******************...**** PP
   S: 332  vlfYkr 337
           +lfY+r
   Q: 775  LLFYER 780
           ****98 PP
   
Organism Felis catus
Protein Sequence
(Fasta)
SVGFTCPHVN LAISVNHVKK AIAENVWSVC SDCLRERRFC DGQPVLSSDI WLCLKCGFQG 60
CGRNSESHHS VKHYKNQRTE SHCITISLST WIIWCYECDE KLSTHCNKKV LAQTVDFLQK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Fca-035947|DUB,USP|Felis catus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TCAGTAGGTT TCACTTGCCC ACATGTAAAT CTTGCCATCA GTGTGAATCA TGTGAAGAAA 60
GCAATAGCTG AGAATGTGTG GTCAGTTTGC TCCGACTGTT TAAGGGAAAG AAGATTCTGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Fca-035947|DUB,USP|Felis catus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00443--UCH
PF02148--zf-UBP
SMART

SM00290--ZnF_UBP
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0006281--P:DNA repair
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002331 Ailuropoda melanoleuca 77.86 0.00e+00 1195.00
IUUC-Apl-003512 Anas platyrhynchos 65.74 0.00e+00 982.00
IUUC-Aca-004284 Anolis carolinensis 60.67 0.00e+00 905.00
IUUC-Ame-010735 Astyanax mexicanus 46.11 5.00e-106 377.00
IUUC-Bta-012880 Bos taurus 81.17 0.00e+00 1216.00
IUUC-Cja-019144 Callithrix jacchus 78.27 0.00e+00 1213.00
IUUC-Cfa-020971 Canis familiaris 86.23 0.00e+00 722.00
IUUC-Cpo-022497 Cavia porcellus 66.50 0.00e+00 980.00
IUUC-Csa-023910 Chlorocebus sabaeus 77.28 0.00e+00 1110.00
IUUC-Cho-024358 Choloepus hoffmanni 59.60 4.00e-109 388.00
IUUC-Dre-028106 Danio rerio 62.43 1.00e-141 497.00
IUUC-Dno-029456 Dasypus novemcinctus 71.54 0.00e+00 670.00
IUUC-Dor-030438 Dipodomys ordii 66.80 0.00e+00 911.00
IUUC-Dme-031870 Drosophila melanogaster 50.31 4.00e-35 143.00
IUUC-Ete-032736 Echinops telfairi 64.51 0.00e+00 950.00
IUUC-Eca-034211 Equus caballus 80.81 0.00e+00 1262.00
IUUC-Eeu-034797 Erinaceus europaeus 76.50 2.00e-84 306.00
IUUC-Fal-037199 Ficedula albicollis 66.28 0.00e+00 845.00
IUUC-Gmo-039228 Gadus morhua 63.33 6.00e-139 488.00
IUUC-Gga-040823 Gallus gallus 64.45 1.00e-168 585.00
IUUC-Gac-042406 Gasterosteus aculeatus 53.23 0.00e+00 770.00
IUUC-Ggo-045402 Gorilla gorilla 77.92 0.00e+00 1194.00
IUUC-Hsa-046430 Homo sapiens 77.82 0.00e+00 1193.00
IUUC-Itr-048855 Ictidomys tridecemlineatus 77.95 0.00e+00 721.00
IUUC-Lch-049547 Latimeria chalumnae 57.23 0.00e+00 857.00
IUUC-Loc-052842 Lepisosteus oculatus 56.96 0.00e+00 846.00
IUUC-Laf-053988 Loxodonta africana 78.63 0.00e+00 1218.00
IUUC-Mcc-055491 Macaca mulatta 73.95 0.00e+00 1124.00
IUUC-Meu-056256 Macropus eugenii 63.65 3.00e-176 612.00
IUUC-Mla-059026 Melampsora laricipopulina 29.46 4.00e-16 79.70
IUUC-Mga-059833 Meleagris gallopavo 61.08 2.00e-170 592.00
IUUC-Mmr-060952 Microcebus murinus 76.97 0.00e+00 1181.00
IUUC-Mdo-062642 Monodelphis domestica 68.01 0.00e+00 1007.00
IUUC-Mmu-063945 Mus musculus 74.59 0.00e+00 1142.00
IUUC-Mpu-065944 Mustela putorius furo 81.81 0.00e+00 1207.00
IUUC-Mlu-067049 Myotis lucifugus 80.56 0.00e+00 1207.00
IUUC-Nle-069828 Nomascus leucogenys 77.66 0.00e+00 1194.00
IUUC-Opr-070672 Ochotona princeps 65.19 9.00e-117 414.00
IUUC-Ont-072121 Oreochromis niloticus 52.62 0.00e+00 741.00
IUUC-Oan-073656 Ornithorhynchus anatinus 62.93 0.00e+00 963.00
IUUC-Ocu-074323 Oryctolagus cuniculus 76.59 0.00e+00 1158.00
IUUC-Ola-087238 Oryzias latipes 53.86 0.00e+00 777.00
IUUC-Oga-088379 Otolemur garnettii 72.85 0.00e+00 1096.00
IUUC-Oar-089718 Ovis aries 81.47 0.00e+00 1220.00
IUUC-Ptr-091358 Pan troglodytes 78.27 0.00e+00 1200.00
IUUC-Pan-092023 Papio anubis 78.14 0.00e+00 1199.00
IUUC-Psi-093256 Pelodiscus sinensis 63.78 0.00e+00 951.00
IUUC-Pfo-097285 Poecilia formosa 50.99 0.00e+00 707.00
IUUC-Pab-098539 Pongo abelii 77.89 0.00e+00 1195.00
IUUC-Pca-100610 Procavia capensis 67.31 0.00e+00 906.00
IUUC-Pva-102985 Pteropus vampyrus 75.57 0.00e+00 1145.00
IUUC-Rno-105538 Rattus norvegicus 74.21 0.00e+00 1139.00
IUUC-Sha-107022 Sarcophilus harrisii 68.42 5.00e-161 561.00
IUUC-Sja-107712 Schizosaccharomyces japonicus 31.16 6.00e-20 92.80
IUUC-Spo-108149 Schizosaccharomyces pombe 30.88 3.00e-21 97.10
IUUC-Sar-113637 Sorex araneus 69.12 0.00e+00 978.00
IUUC-Ssc-115870 Sus scrofa 80.79 0.00e+00 1269.00
IUUC-Tgu-116907 Taeniopygia guttata 65.99 0.00e+00 979.00
IUUC-Tru-117835 Takifugu rubripes 53.87 5.00e-108 385.00
IUUC-Tsy-118869 Tarsius syrichta 78.02 0.00e+00 1085.00
IUUC-Tni-119716 Tetraodon nigroviridis 64.57 1.00e-93 337.00
IUUC-Tbe-128041 Tupaia belangeri 66.89 0.00e+00 877.00
IUUC-Ttr-128901 Tursiops truncatus 79.64 0.00e+00 1207.00
IUUC-Vpa-130331 Vicugna pacos 81.33 0.00e+00 1204.00
IUUC-Xtr-131794 Xenopus tropicalis 51.69 0.00e+00 765.00
Created Date 25-Jun-2017

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