iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	3.90e-15	56.3	36	101

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmele.esksklmveikdvqpevfrallkFlYtgklden 68
           +D+ +vv++++f+ah++vLaa+S +F++lf ++le +s  ++ +ei+ +  + f+++l+++Yt k++ +
   Q: 36   CDIAIVVEDVKFRAHRCVLAACSTYFKKLF-KKLEvDS--SSVIEIDFLRSDIFEEVLNYMYTAKISVK 101
           8*****************************.4566466..89*****9****************99865 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MEFFISMSET IKYNDDDHKT LFLKTLNEQR LEGEFCDIAI VVEDVKFRAH RCVLAACSTY 60
FKKLFKKLEV DSSSVIEIDF LRSDIFEEVL NYMYTAKISV KKEDVNLMMS SGQILGIRFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTCAGCGGG AGCTATTTGT TAAGGAAGTA ATCTGAGGCT CGTTGCACCC GGCGGATGCA 60
CGGCTTCGAA ATGCGAGTGT GGGCTCCCCA CGCGCGGACT GCGCCCCAGG TCTTGCACGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR004039--Rubredoxin-type_fold
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0016235--C:aggresome
GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0046872--F:metal ion binding
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0044212--F:transcription regulatory region DNA binding
GO:0003279--P:cardiac septum development
GO:0060976--P:coronary vasculature development
GO:0003170--P:heart valve development
GO:0045892--P:negative regulation of transcription, DNA-templated

KEGG

rno:282825

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001753	Ailuropoda melanoleuca	99.33	0.00e+00	845.00
IUUC-Apl-003283	Anas platyrhynchos	93.99	0.00e+00	815.00
IUUC-Aca-004393	Anolis carolinensis	92.87	0.00e+00	808.00
IUUC-Ame-011467	Astyanax mexicanus	75.11	0.00e+00	631.00
IUUC-Bta-012973	Bos taurus	98.88	0.00e+00	841.00
IUUC-Cja-019628	Callithrix jacchus	99.33	0.00e+00	848.00
IUUC-Cfa-020023	Canis familiaris	99.55	0.00e+00	847.00
IUUC-Csa-023821	Chlorocebus sabaeus	99.33	0.00e+00	848.00
IUUC-Cho-024977	Choloepus hoffmanni	99.11	0.00e+00	844.00
IUUC-Dre-027417	Danio rerio	76.51	3.00e-180	624.00
IUUC-Dor-030435	Dipodomys ordii	99.11	0.00e+00	847.00
IUUC-Ete-032628	Echinops telfairi	97.10	0.00e+00	826.00
IUUC-Eca-033287	Equus caballus	99.11	0.00e+00	845.00
IUUC-Fca-036098	Felis catus	99.11	0.00e+00	847.00
IUUC-Fal-037053	Ficedula albicollis	94.22	0.00e+00	796.00
IUUC-Gmo-039037	Gadus morhua	63.35	8.00e-105	373.00
IUUC-Gga-040669	Gallus gallus	94.89	0.00e+00	824.00
IUUC-Gac-041324	Gasterosteus aculeatus	65.65	4.00e-153	534.00
IUUC-Ggo-045482	Gorilla gorilla	99.33	0.00e+00	848.00
IUUC-Hsa-046032	Homo sapiens	99.33	0.00e+00	848.00
IUUC-Itr-048659	Ictidomys tridecemlineatus	98.44	0.00e+00	838.00
IUUC-Lch-050626	Latimeria chalumnae	87.36	0.00e+00	758.00
IUUC-Loc-052339	Lepisosteus oculatus	81.21	0.00e+00	700.00
IUUC-Laf-054425	Loxodonta africana	87.50	0.00e+00	707.00
IUUC-Mcc-054963	Macaca mulatta	99.33	0.00e+00	848.00
IUUC-Meu-056097	Macropus eugenii	95.32	0.00e+00	835.00
IUUC-Mga-060044	Meleagris gallopavo	94.15	0.00e+00	813.00
IUUC-Mmr-060645	Microcebus murinus	99.11	0.00e+00	848.00
IUUC-Mdo-062972	Monodelphis domestica	95.32	0.00e+00	837.00
IUUC-Mmu-064130	Mus musculus	100.00	0.00e+00	850.00
IUUC-Mpu-066481	Mustela putorius furo	99.33	0.00e+00	848.00
IUUC-Mlu-067950	Myotis lucifugus	85.27	0.00e+00	707.00
IUUC-Nle-069887	Nomascus leucogenys	99.11	0.00e+00	846.00
IUUC-Ont-071683	Oreochromis niloticus	70.44	8.00e-178	616.00
IUUC-Oan-073523	Ornithorhynchus anatinus	89.53	0.00e+00	777.00
IUUC-Ocu-074079	Oryctolagus cuniculus	99.11	0.00e+00	847.00
IUUC-Ola-087045	Oryzias latipes	52.12	3.00e-121	427.00
IUUC-Oga-088178	Otolemur garnettii	99.33	0.00e+00	845.00
IUUC-Ptr-091539	Pan troglodytes	98.89	0.00e+00	844.00
IUUC-Pan-092044	Papio anubis	99.33	0.00e+00	848.00
IUUC-Psi-093698	Pelodiscus sinensis	93.90	0.00e+00	814.00
IUUC-Pma-094150	Petromyzon marinus	41.11	2.00e-88	318.00
IUUC-Pfo-096504	Poecilia formosa	71.75	1.00e-180	625.00
IUUC-Pab-098387	Pongo abelii	99.33	0.00e+00	848.00
IUUC-Pop-098852	Populus trichocarpa	39.24	7.00e-08	52.40
IUUC-Pca-100494	Procavia capensis	99.11	0.00e+00	846.00
IUUC-Pva-102568	Pteropus vampyrus	99.33	0.00e+00	848.00
IUUC-Sha-107503	Sarcophilus harrisii	94.48	0.00e+00	625.00
IUUC-Tru-118010	Takifugu rubripes	70.73	2.00e-171	594.00
IUUC-Tni-120503	Tetraodon nigroviridis	71.11	2.00e-176	611.00
IUUC-Tca-121013	Theobroma cacao	34.67	1.00e-05	45.10
IUUC-Tbe-127288	Tupaia belangeri	98.89	0.00e+00	845.00
IUUC-Xtr-132271	Xenopus tropicalis	88.74	0.00e+00	771.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence