iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053683

UUCD1 version

UUC-LoA-00017

Ensembl Protein ID

ENSLAFP00000000495.4

UniProt Accession

G3SM06; G3SM06_LOXAF

Protein Name

Uncharacterized protein

Gene Name

PHF14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000000589.4	ENSLAFT00000000589.4	ENSLAFP00000000495.4
ENSLAFG00000000589.4	ENSLAFT00000034732.1	ENSLAFP00000021962.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.00e-17	63.5	875	925

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCrs 53
            C+ C+ +g++e +lv+C++Cr ++H++Cl ++  ++ p+++   wiC++C+s
   Q: 875  ECATCKGTGDNE-NLVRCDECRLCYHFGCLDPP-LKKSPKQTGygWICQECDS 925
           6********977.7*******************.77777776679******86 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

VDRSSKRRQV KPLAASLLEA LDYDSSDDSD FKVGDASDSE GSGNGSEDPS KDSGEGSCSD 60
SEENILEEEL NENIKVKEEQ IKNSAEEETL SSEKQLIKME KKEEEENGER PRKKKEKEKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGATCGCA GCTCCAAGAG GAGGCAGGTG AAGCCTTTGG CAGCTTCTCT GCTAGAAGCT 60
CTCGATTATG ATAGTTCAGA TGACAGTGAT TTTAAAGTTG GAGATGCTTC AGGTAAATGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00628--PHD

SMART

SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0048286--P:lung alveolus development
GO:2000791--P:negative regulation of mesenchymal cell proliferation involved in lung development
GO:2000584--P:negative regulation of platelet-derived growth factor receptor-alpha signaling pathway
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001978	Ailuropoda melanoleuca	94.40	0.00e+00	1422.00
IUUC-Apl-003491	Anas platyrhynchos	93.61	0.00e+00	1308.00
IUUC-Aca-004470	Anolis carolinensis	90.12	0.00e+00	1282.00
IUUC-Ame-011188	Astyanax mexicanus	82.48	0.00e+00	1046.00
IUUC-Bta-012312	Bos taurus	94.38	0.00e+00	1358.00
IUUC-Cel-018258	Caenorhabditis elegans	28.26	2.00e-47	183.00
IUUC-Cja-019931	Callithrix jacchus	96.56	0.00e+00	1442.00
IUUC-Cfa-021102	Canis familiaris	97.59	0.00e+00	1393.00
IUUC-Csa-023396	Chlorocebus sabaeus	98.03	0.00e+00	1389.00
IUUC-Cin-025300	Ciona intestinalis	34.39	1.00e-73	270.00
IUUC-Csv-026365	Ciona savignyi	60.71	1.00e-15	73.90
IUUC-Dre-028450	Danio rerio	82.43	0.00e+00	1040.00
IUUC-Dno-029245	Dasypus novemcinctus	95.72	0.00e+00	1377.00
IUUC-Dme-031650	Drosophila melanogaster	39.04	1.00e-118	421.00
IUUC-Ete-032829	Echinops telfairi	83.25	0.00e+00	1136.00
IUUC-Eca-033527	Equus caballus	98.54	0.00e+00	1395.00
IUUC-Eeu-035092	Erinaceus europaeus	84.55	0.00e+00	998.00
IUUC-Fal-037349	Ficedula albicollis	92.98	0.00e+00	1309.00
IUUC-Gmo-038924	Gadus morhua	80.51	0.00e+00	1016.00
IUUC-Gga-040604	Gallus gallus	93.11	0.00e+00	1313.00
IUUC-Gac-041895	Gasterosteus aculeatus	79.88	0.00e+00	1019.00
IUUC-Ggo-044724	Gorilla gorilla	92.68	0.00e+00	1267.00
IUUC-Hsa-046740	Homo sapiens	99.20	0.00e+00	1394.00
IUUC-Lch-050481	Latimeria chalumnae	91.80	0.00e+00	1229.00
IUUC-Loc-052530	Lepisosteus oculatus	84.07	0.00e+00	1238.00
IUUC-Mcc-055254	Macaca mulatta	97.90	0.00e+00	1389.00
IUUC-Meu-056124	Macropus eugenii	71.47	0.00e+00	899.00
IUUC-Mmr-061716	Microcebus murinus	98.94	0.00e+00	1400.00
IUUC-Mmu-064063	Mus musculus	97.72	0.00e+00	1373.00
IUUC-Mpu-065850	Mustela putorius furo	95.72	0.00e+00	1367.00
IUUC-Mlu-067977	Myotis lucifugus	97.32	0.00e+00	1301.00
IUUC-Nle-070024	Nomascus leucogenys	96.77	0.00e+00	1438.00
IUUC-Opr-070669	Ochotona princeps	83.36	0.00e+00	1059.00
IUUC-Ont-072407	Oreochromis niloticus	73.08	0.00e+00	1133.00
IUUC-Ola-087564	Oryzias latipes	82.75	0.00e+00	1115.00
IUUC-Oga-088503	Otolemur garnettii	96.63	0.00e+00	1342.00
IUUC-Oar-090254	Ovis aries	95.37	0.00e+00	1447.00
IUUC-Ptr-090811	Pan troglodytes	99.16	0.00e+00	1306.00
IUUC-Psi-093869	Pelodiscus sinensis	94.24	0.00e+00	1334.00
IUUC-Pma-094703	Petromyzon marinus	61.14	0.00e+00	748.00
IUUC-Pfo-097375	Poecilia formosa	83.33	0.00e+00	1007.00
IUUC-Pab-098645	Pongo abelii	99.20	0.00e+00	1394.00
IUUC-Pca-100931	Procavia capensis	88.34	0.00e+00	907.00
IUUC-Pva-102902	Pteropus vampyrus	93.48	0.00e+00	1355.00
IUUC-Rno-105725	Rattus norvegicus	96.71	0.00e+00	1355.00
IUUC-Sha-107008	Sarcophilus harrisii	92.75	0.00e+00	1309.00
IUUC-Sar-113710	Sorex araneus	87.13	0.00e+00	996.00
IUUC-Ssc-116271	Sus scrofa	96.87	0.00e+00	1385.00
IUUC-Tru-117706	Takifugu rubripes	82.53	0.00e+00	1079.00
IUUC-Tsy-118886	Tarsius syrichta	96.40	0.00e+00	1406.00
IUUC-Tni-120623	Tetraodon nigroviridis	81.37	0.00e+00	986.00
IUUC-Tbe-127618	Tupaia belangeri	86.42	6.00e-122	431.00
IUUC-Ttr-129058	Tursiops truncatus	98.88	0.00e+00	1313.00
IUUC-Vpa-130327	Vicugna pacos	97.74	0.00e+00	1397.00
IUUC-Xtr-132030	Xenopus tropicalis	77.49	0.00e+00	1223.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence