iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062419

UUCD1 version

UUC-MoD-00766

Ensembl Protein ID

ENSMODP00000010174.2

UniProt Accession

F7E4D6; F7E4D6_MONDO

Protein Name

Uncharacterized protein

Gene Name

KLHL23

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000008183.3	ENSMODT00000010370.3	ENSMODP00000010174.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	9.40e-17	61.3	36	102
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.40e-08	33.9	136	167

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvg.geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +D++l++  g  f++hk+vLaa+S +F+a+f+ +++e+  k+++++ ++ +ev++ l+++ Yt+++++
   Q: 36   TDITLQCPsGGIFHCHKAVLAACSNYFKAMFTADMKEKF-KNKIKLPGIHHEVLEGLINYAYTSQIRI 102
           799****99*****************************9.************************9976 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nc+g+ +fA+ + cp+L +  ++++l+ Fk
   Q: 136  VDNCIGMHSFAEFHVCPELEKESRRMLLSRFK 167
           69***************************997 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MALKGQEDYV YLFKDPSHPL DFLEAFRTFY LDGLFTDITL QCPSGGIFHC HKAVLAACSN 60
YFKAMFTADM KEKFKNKIKL PGIHHEVLEG LINYAYTSQI RITQRNVQSL LEAADLLQFF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCTGGAGG CTGCACTACA GCTTGGCTCC AGCCCTGGCG GCCCCAGGTT TTTCCTGCAG 60
GCTGCCAGCT TAACCCCTGA TGCGCCGATC TGACACAGAG GCTATTCCTG AGGTGCGAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

KEGG

mdo:100017617

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001639	Ailuropoda melanoleuca	89.80	0.00e+00	1069.00
IUUC-Apl-003948	Anas platyrhynchos	77.25	0.00e+00	858.00
IUUC-Aca-005045	Anolis carolinensis	76.88	0.00e+00	927.00
IUUC-Ame-011013	Astyanax mexicanus	62.92	0.00e+00	769.00
IUUC-Bta-013159	Bos taurus	90.34	0.00e+00	1070.00
IUUC-Bol-015209	Brassica oleracea	30.23	2.00e-14	72.80
IUUC-Bra-017656	Brassica rapa	30.23	2.00e-14	72.80
IUUC-Cja-018886	Callithrix jacchus	89.96	0.00e+00	1071.00
IUUC-Cfa-020205	Canis familiaris	89.96	0.00e+00	1073.00
IUUC-Cpo-022295	Cavia porcellus	89.61	0.00e+00	1065.00
IUUC-Cho-025089	Choloepus hoffmanni	88.79	0.00e+00	863.00
IUUC-Dre-027681	Danio rerio	61.07	0.00e+00	748.00
IUUC-Dno-029078	Dasypus novemcinctus	88.35	0.00e+00	858.00
IUUC-Ete-033011	Echinops telfairi	77.90	0.00e+00	887.00
IUUC-Eca-033213	Equus caballus	89.96	0.00e+00	1072.00
IUUC-Fca-035884	Felis catus	89.61	0.00e+00	1069.00
IUUC-Fal-036897	Ficedula albicollis	77.08	0.00e+00	922.00
IUUC-Gmo-038594	Gadus morhua	57.37	0.00e+00	706.00
IUUC-Gga-040791	Gallus gallus	75.45	0.00e+00	924.00
IUUC-Gac-042512	Gasterosteus aculeatus	60.14	0.00e+00	736.00
IUUC-Ggo-044837	Gorilla gorilla	89.78	0.00e+00	1071.00
IUUC-Hsa-046231	Homo sapiens	89.96	0.00e+00	1071.00
IUUC-Itr-048084	Ictidomys tridecemlineatus	90.68	0.00e+00	1077.00
IUUC-Lch-050412	Latimeria chalumnae	73.67	0.00e+00	906.00
IUUC-Loc-052033	Lepisosteus oculatus	68.26	0.00e+00	826.00
IUUC-Laf-053908	Loxodonta africana	89.78	0.00e+00	1069.00
IUUC-Mcc-054734	Macaca mulatta	89.78	0.00e+00	1070.00
IUUC-Meu-055982	Macropus eugenii	99.10	0.00e+00	1160.00
IUUC-Mga-059670	Meleagris gallopavo	74.78	0.00e+00	912.00
IUUC-Mmr-060692	Microcebus murinus	90.14	0.00e+00	1071.00
IUUC-Mmu-063752	Mus musculus	89.07	0.00e+00	1061.00
IUUC-Mpu-066515	Mustela putorius furo	89.78	0.00e+00	1071.00
IUUC-Mlu-068004	Myotis lucifugus	87.43	0.00e+00	1037.00
IUUC-Nle-069163	Nomascus leucogenys	89.96	0.00e+00	1071.00
IUUC-Opr-070823	Ochotona princeps	88.35	0.00e+00	857.00
IUUC-Ont-071629	Oreochromis niloticus	61.74	0.00e+00	750.00
IUUC-Oan-072841	Ornithorhynchus anatinus	86.02	0.00e+00	1023.00
IUUC-Ocu-074300	Oryctolagus cuniculus	89.96	0.00e+00	1072.00
IUUC-Ola-087025	Oryzias latipes	57.65	0.00e+00	720.00
IUUC-Oga-088442	Otolemur garnettii	88.85	0.00e+00	1021.00
IUUC-Oar-089237	Ovis aries	90.34	0.00e+00	1068.00
IUUC-Ptr-091541	Pan troglodytes	89.78	0.00e+00	1069.00
IUUC-Psi-093748	Pelodiscus sinensis	78.85	0.00e+00	955.00
IUUC-Pma-094302	Petromyzon marinus	45.08	4.00e-102	365.00
IUUC-Pfo-097039	Poecilia formosa	61.58	0.00e+00	729.00
IUUC-Pab-098280	Pongo abelii	89.61	0.00e+00	1066.00
IUUC-Pca-100840	Procavia capensis	81.18	0.00e+00	944.00
IUUC-Pva-102152	Pteropus vampyrus	89.78	0.00e+00	1068.00
IUUC-Rno-105710	Rattus norvegicus	88.67	0.00e+00	1058.00
IUUC-Sha-106991	Sarcophilus harrisii	98.57	0.00e+00	1159.00
IUUC-Sar-112931	Sorex araneus	89.25	0.00e+00	1068.00
IUUC-Ssc-116016	Sus scrofa	88.55	0.00e+00	1056.00
IUUC-Tgu-116999	Taeniopygia guttata	77.42	0.00e+00	931.00
IUUC-Tsy-119071	Tarsius syrichta	89.43	0.00e+00	1063.00
IUUC-Tni-120149	Tetraodon nigroviridis	57.04	0.00e+00	661.00
IUUC-Tbe-127651	Tupaia belangeri	90.14	0.00e+00	1073.00
IUUC-Ttr-128402	Tursiops truncatus	89.96	0.00e+00	1071.00
IUUC-Vpa-130186	Vicugna pacos	88.53	0.00e+00	1053.00
IUUC-Xtr-132379	Xenopus tropicalis	71.33	0.00e+00	885.00
IUUC-Xma-133185	Xiphophorus maculatus	60.86	0.00e+00	738.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence