iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000007152.3	ENSMMUT00000009986.3	ENSMMUP00000009372.3
ENSMMUG00000007152.3	ENSMMUT00000009987.3	ENSMMUP00000009373.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	5.30e-12	46.1	330	357
ULD/UDP/UBQ/UBQ_Other	1.00e-11	45.6	234	286

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 3    aqWaCsaCTflNePeavkCemCsrpRgc 30
           + W C++CTf+N+P++++CemCs++R+c
   Q: 330  PSWPCPSCTFINAPSRPGCEMCSTQRPC 357
           68*************************9 PP

ULD/UDP/UBQ/UBQ_Other

   S: 12   eltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdg 64
           +  l+v+p++tVa L+e+++++lg+pp+ qr+++ G++L  + ++La+yg++++
   Q: 234  HVALQVHPHCTVAALQEQVFSELGFPPAVQRWVI-GRCLcVPERSLASYGVRQD 286
           556779****************************.**************99754 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MAPPAGGAAA ASDLGSAAVL LTVHAAVRLL GARPDAEAQL RRLQLSADPE RPGRFRLELL 60
DAGPGAVNLE WPLESVSYTI RGPTQHELQP PPGGPGTLSL HFLNPQEAQR WAVLVRGATV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCCGC CAGCGGGCGG GGCGGCGGCG GCCTCGGACT TGGGCTCGGC CGCAGTGCTC 60
TTGACTGTGC ACGCCGCTGT GAGGCTGCTG GGCGCCAGGC CAGACGCCGA GGCACAGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR031912--Sharpin_PH
IPR029071--Ubiquitin-rel_dom
IPR001876--Znf_RanBP2

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2

Pfam

PF16764--Sharpin_PH

SMART

SM00547--ZnF_RBZ

Gene Ontology

GO:0005829--C:cytosol
GO:0071797--C:LUBAC complex
GO:0043130--F:ubiquitin binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0030262--P:apoptotic nuclear changes
GO:0031424--P:keratinization
GO:0007005--P:mitochondrion organization
GO:0050728--P:negative regulation of inflammatory response
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0097039--P:protein linear polyubiquitination
GO:2000348--P:regulation of CD40 signaling pathway
GO:0010803--P:regulation of tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001223	Ailuropoda melanoleuca	73.74	8.00e-118	416.00
IUUC-Apl-004151	Anas platyrhynchos	68.09	2.00e-17	80.10
IUUC-Bta-012948	Bos taurus	74.26	3.00e-127	448.00
IUUC-Cja-019031	Callithrix jacchus	80.83	1.00e-122	432.00
IUUC-Cfa-020863	Canis familiaris	69.27	7.00e-101	360.00
IUUC-Cpo-022499	Cavia porcellus	67.63	2.00e-117	415.00
IUUC-Csa-023641	Chlorocebus sabaeus	87.57	2.00e-145	508.00
IUUC-Dre-027612	Danio rerio	39.86	2.00e-36	146.00
IUUC-Dno-029459	Dasypus novemcinctus	64.58	1.00e-49	190.00
IUUC-Dor-030914	Dipodomys ordii	65.28	1.00e-79	290.00
IUUC-Ete-032940	Echinops telfairi	69.51	5.00e-94	337.00
IUUC-Eca-033537	Equus caballus	75.21	5.00e-125	440.00
IUUC-Eeu-035176	Erinaceus europaeus	71.43	2.00e-54	206.00
IUUC-Fca-035971	Felis catus	71.73	1.00e-109	389.00
IUUC-Gmo-039219	Gadus morhua	38.46	1.00e-49	190.00
IUUC-Gac-041562	Gasterosteus aculeatus	52.76	3.00e-27	115.00
IUUC-Ggo-044678	Gorilla gorilla	80.82	5.00e-138	483.00
IUUC-Hsa-046578	Homo sapiens	84.17	7.00e-144	503.00
IUUC-Itr-047913	Ictidomys tridecemlineatus	70.41	1.00e-117	416.00
IUUC-Meu-055912	Macropus eugenii	52.15	2.00e-57	216.00
IUUC-Mmr-060584	Microcebus murinus	75.82	4.00e-128	451.00
IUUC-Mdo-062191	Monodelphis domestica	54.79	2.00e-74	272.00
IUUC-Mmu-063740	Mus musculus	65.92	6.00e-109	387.00
IUUC-Mpu-066878	Mustela putorius furo	69.91	3.00e-102	365.00
IUUC-Mlu-067878	Myotis lucifugus	74.18	2.00e-126	445.00
IUUC-Nle-069748	Nomascus leucogenys	93.57	8.00e-130	456.00
IUUC-Ont-072270	Oreochromis niloticus	37.91	1.00e-47	183.00
IUUC-Obr-076087	Oryza brachyantha	58.33	3.00e-04	38.50
IUUC-Oga-088300	Otolemur garnettii	74.01	2.00e-132	465.00
IUUC-Oar-089549	Ovis aries	73.80	4.00e-127	447.00
IUUC-Ptr-090961	Pan troglodytes	93.21	3.00e-131	461.00
IUUC-Pan-092687	Papio anubis	89.20	4.00e-153	533.00
IUUC-Pab-097872	Pongo abelii	93.93	3.00e-128	451.00
IUUC-Pca-100363	Procavia capensis	58.45	2.00e-68	253.00
IUUC-Pva-102595	Pteropus vampyrus	78.93	4.00e-109	387.00
IUUC-Rno-105856	Rattus norvegicus	65.23	4.00e-104	371.00
IUUC-Sha-106838	Sarcophilus harrisii	52.34	9.00e-63	234.00
IUUC-Sar-113611	Sorex araneus	83.87	3.00e-22	99.40
IUUC-Ssc-116263	Sus scrofa	70.46	2.00e-117	415.00
IUUC-Tru-118089	Takifugu rubripes	40.38	4.00e-53	201.00
IUUC-Tni-120004	Tetraodon nigroviridis	39.34	8.00e-43	167.00
IUUC-Tbe-127471	Tupaia belangeri	74.07	2.00e-102	365.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence