iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-073639

Ensembl Protein ID

ENSOANP00000009902.2

UniProt Accession

F6XPF0; F6XPF0_ORNAN

Protein Name

Uncharacterized protein

Gene Name

IFIH1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000006194.2	ENSOANT00000009904.2	ENSOANP00000009902.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	6.30e-21	75.0	41	111

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 3    eeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL...vqkegWfref 72
           e +r+ll+++++r+   ++vt+ ld  l+ fl  e+k +i ++aet g   a+e+LL  L    +  g  ref
   Q: 41   EAFRQLLFCFRPRLQASIQVTPLLD-HLT-FLDGEVKDEIKRIAETRGRPRAVERLLAALergDWPPGYRREF 111
           789**********************.***.***************************9997766666666666 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MEAPPRRGCH QGRGIESESW GRKVAEGAAT TAMARGYSSE EAFRQLLFCF RPRLQASIQV 60
TPLLDHLTFL DGEVKDEIKR IAETRGRPRA VERLLAALER GDWPPGYRRE FVTALRLVGC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTGGATCTC CCCCGGCGCT TAGAACAGCG CTCCGCCCAT AGTAAGCGCT TAACAGATAC 60
CAACGTTATT CAATTATTAT TGCAGCGGGA TGGAGGCCCC GCCTCGCCGG GGCTGTCACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0043021--F:ribonucleoprotein complex binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0039530--P:MDA-5 signaling pathway
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001336	Ailuropoda melanoleuca	65.96	0.00e+00	1129.00
IUUC-Apl-003900	Anas platyrhynchos	60.39	0.00e+00	1029.00
IUUC-Aca-005329	Anolis carolinensis	58.49	0.00e+00	894.00
IUUC-Ame-011305	Astyanax mexicanus	47.91	0.00e+00	765.00
IUUC-Bta-012361	Bos taurus	66.38	0.00e+00	1108.00
IUUC-Cja-018760	Callithrix jacchus	65.79	0.00e+00	1077.00
IUUC-Cfa-020321	Canis familiaris	65.01	0.00e+00	1078.00
IUUC-Cpo-022450	Cavia porcellus	64.52	0.00e+00	1086.00
IUUC-Cre-022916	Chlamydomonas reinhardtii	29.85	5.00e-12	66.60
IUUC-Csa-024194	Chlorocebus sabaeus	66.24	0.00e+00	1073.00
IUUC-Cho-024364	Choloepus hoffmanni	59.05	0.00e+00	756.00
IUUC-Dre-028305	Danio rerio	56.89	4.00e-177	614.00
IUUC-Dno-029831	Dasypus novemcinctus	64.62	0.00e+00	1085.00
IUUC-Dor-030410	Dipodomys ordii	74.00	0.00e+00	902.00
IUUC-Ete-032950	Echinops telfairi	65.59	6.00e-163	567.00
IUUC-Eca-034279	Equus caballus	66.28	0.00e+00	1110.00
IUUC-Eeu-034678	Erinaceus europaeus	63.84	0.00e+00	1119.00
IUUC-Fca-035618	Felis catus	72.29	0.00e+00	653.00
IUUC-Fal-037106	Ficedula albicollis	60.30	0.00e+00	967.00
IUUC-Fso-038398	Fusarium solani	26.82	7.00e-29	122.00
IUUC-Gmo-038598	Gadus morhua	54.89	0.00e+00	655.00
IUUC-Gga-040467	Gallus gallus	60.77	0.00e+00	1040.00
IUUC-Gac-042316	Gasterosteus aculeatus	48.51	0.00e+00	735.00
IUUC-Ggo-045461	Gorilla gorilla	66.42	0.00e+00	1083.00
IUUC-Hsa-045771	Homo sapiens	66.31	0.00e+00	1080.00
IUUC-Itr-048762	Ictidomys tridecemlineatus	66.74	0.00e+00	1112.00
IUUC-Lch-049913	Latimeria chalumnae	69.15	0.00e+00	804.00
IUUC-Loc-052768	Lepisosteus oculatus	54.72	0.00e+00	872.00
IUUC-Laf-053933	Loxodonta africana	65.88	0.00e+00	1108.00
IUUC-Mcc-054695	Macaca mulatta	66.24	0.00e+00	1077.00
IUUC-Meu-056829	Macropus eugenii	69.64	0.00e+00	890.00
IUUC-Mga-059205	Meleagris gallopavo	61.03	0.00e+00	1030.00
IUUC-Mmr-060703	Microcebus murinus	65.08	0.00e+00	1107.00
IUUC-Mdo-063079	Monodelphis domestica	65.02	0.00e+00	1151.00
IUUC-Mmu-064066	Mus musculus	64.15	0.00e+00	1120.00
IUUC-Mpu-066261	Mustela putorius furo	65.40	0.00e+00	1097.00
IUUC-Mlu-068196	Myotis lucifugus	65.64	0.00e+00	1063.00
IUUC-Nfi-068405	Neosartorya fischeri	27.13	1.00e-29	125.00
IUUC-Nle-069479	Nomascus leucogenys	65.36	0.00e+00	1059.00
IUUC-Opr-070717	Ochotona princeps	62.04	0.00e+00	920.00
IUUC-Ont-071702	Oreochromis niloticus	48.46	0.00e+00	767.00
IUUC-Ocu-074521	Oryctolagus cuniculus	66.00	0.00e+00	1115.00
IUUC-Ola-086351	Oryzias latipes	46.40	0.00e+00	668.00
IUUC-Oga-088539	Otolemur garnettii	65.89	0.00e+00	1105.00
IUUC-Oar-090186	Ovis aries	66.28	0.00e+00	1086.00
IUUC-Ptr-090575	Pan troglodytes	65.57	0.00e+00	1056.00
IUUC-Pan-092371	Papio anubis	66.67	0.00e+00	1083.00
IUUC-Psi-093072	Pelodiscus sinensis	62.43	0.00e+00	1066.00
IUUC-Pma-094345	Petromyzon marinus	45.26	1.00e-99	355.00
IUUC-Pfo-096401	Poecilia formosa	57.07	1.00e-175	609.00
IUUC-Pab-097623	Pongo abelii	65.47	0.00e+00	1065.00
IUUC-Pca-100993	Procavia capensis	60.66	0.00e+00	1003.00
IUUC-Pva-102227	Pteropus vampyrus	61.51	0.00e+00	983.00
IUUC-Pgr-103529	Puccinia graminis	28.65	5.00e-29	123.00
IUUC-Rno-105198	Rattus norvegicus	63.04	0.00e+00	1095.00
IUUC-Sha-107622	Sarcophilus harrisii	67.52	0.00e+00	1164.00
IUUC-Sar-113625	Sorex araneus	73.11	5.00e-134	471.00
IUUC-Tgu-117486	Taeniopygia guttata	59.37	0.00e+00	986.00
IUUC-Tru-118445	Takifugu rubripes	47.14	0.00e+00	730.00
IUUC-Tsy-119512	Tarsius syrichta	63.67	0.00e+00	1012.00
IUUC-Tni-120711	Tetraodon nigroviridis	47.13	0.00e+00	749.00
IUUC-Tbe-127644	Tupaia belangeri	59.72	0.00e+00	948.00
IUUC-Ttr-128989	Tursiops truncatus	62.59	0.00e+00	1063.00
IUUC-Vpa-130587	Vicugna pacos	62.36	0.00e+00	850.00
IUUC-Xtr-132127	Xenopus tropicalis	54.49	0.00e+00	929.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence