iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-117062

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01016981

Gene Name

USP8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000007507.1	ENSTGUT00000007835.1	ENSTGUP00000007754.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.90e-110	368.4	771	1101

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtCYmNS+LQcL n p l+e++++  ++ ++n++n  ++kge+++++  ++++lw ++ k++sp++++ +++k++ +fsg
   Q: 771  TGLRNLGNTCYMNSILQCLCNAPHLAEYFNRnLYQADINRSNFLGHKGEVAEEFGVIMKALWAGQYKYISPKDFKITIGKINDQFSG 857
           7*****************************999****************************************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeed...kselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfl 170
           y+qqD+qE+l fl+d+l+e+l+k +n ++ +ee++d   +s++ ++a+ k+k+ n+s+i+ lFqgq+ks+++cl+c+++s ++e f+
   Q: 858  YSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDhldDSSAAEIAWHKHKQLNESIIVALFQGQFKSTVQCLTCHKRSRTFEAFM 944
           *********************8855555555544440114445555***************************************** PP
   S: 171  dlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpl 257
           +lslp+ +++++   +lq+cL+ f+kee+l+++n++yc++ck ++++ kk++++klP+vL +hLkRfs++ + ++ +k++++v+fpl
   Q: 945  YLSLPLASSSKC---TLQECLRLFSKEEKLTDNNRFYCSHCKTRRDSLKKIEIWKLPPVLLVHLKRFSYDGR-WK-QKLQTSVDFPL 1026
           ***********9...******************************************************996.55.6********** PP
   S: 258  e.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYk 336
           e Ldls++++ p+++    k+Y+L++v +H+G+l++GHY+ay+kn +++ W++fdD++V+e++ ++v++   s aY+lfY+
   Q: 1027 EtLDLSQYVIGPKTS---LKRYNLFSVSNHYGGLDGGHYTAYCKNASKQrWFKFDDHEVSEISASSVKS---SAAYILFYT 1101
           ***********9988...69*************************88778*******************...********8 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MPAVASVPKE LYLSTSLKDL NKKTEVKPEK TSTKSYVQSA LKIFKAAEES RLDGDEEKAY 60
ILYMKYVAVY NLIRKRPDFK QQQDYFHSIL GPTNLKKALD EAEILSDSLK LRYEEAEVRK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCTGCTG TGGCGTCTGT ACCTAAGGAG CTATACCTCT CTACTTCATT GAAAGATCTC 60
AACAAGAAGA CAGAAGTAAA ACCTGAAAAG ACCAGTACAA AAAGGTACAT ATGTTATAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR001763--Rhodanese-like_dom
IPR015063--USP8_dimer
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50206--RHODANESE_3
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00581--Rhodanese
PF00443--UCH
PF08969--USP8_dimer

SMART

SM00450--RHOD

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001661	Ailuropoda melanoleuca	81.21	0.00e+00	917.00
IUUC-Apl-003226	Anas platyrhynchos	84.24	0.00e+00	999.00
IUUC-Aca-004936	Anolis carolinensis	62.75	0.00e+00	1250.00
IUUC-Ago-007959	Ashbya gossypii	35.26	1.00e-54	207.00
IUUC-Acl-008102	Aspergillus clavatus	30.77	6.00e-52	199.00
IUUC-Afl-008604	Aspergillus flavus	31.75	5.00e-51	196.00
IUUC-Ani-009291	Aspergillus nidulans	30.49	1.00e-51	198.00
IUUC-Aor-010098	Aspergillus oryzae	31.75	1.00e-50	194.00
IUUC-Ate-010585	Aspergillus terreus	30.94	3.00e-51	196.00
IUUC-Ame-010960	Astyanax mexicanus	78.89	9.00e-87	311.00
IUUC-Bta-013008	Bos taurus	78.51	0.00e+00	875.00
IUUC-Bol-015281	Brassica oleracea	38.51	5.00e-49	188.00
IUUC-Bra-017228	Brassica rapa	39.40	5.00e-51	194.00
IUUC-Cel-018482	Caenorhabditis elegans	34.69	6.00e-54	205.00
IUUC-Cja-019173	Callithrix jacchus	81.03	0.00e+00	925.00
IUUC-Cfa-021243	Canis familiaris	81.03	0.00e+00	915.00
IUUC-Cpo-021522	Cavia porcellus	61.24	8.00e-151	527.00
IUUC-Cre-022582	Chlamydomonas reinhardtii	44.93	9.00e-83	299.00
IUUC-Csa-023616	Chlorocebus sabaeus	80.69	0.00e+00	914.00
IUUC-Cho-024381	Choloepus hoffmanni	67.85	0.00e+00	736.00
IUUC-Cin-025287	Ciona intestinalis	49.62	4.00e-97	349.00
IUUC-Csv-026253	Ciona savignyi	49.63	1.00e-88	320.00
IUUC-Cne-026821	Cryptococcus neoformans	41.00	3.00e-76	280.00
IUUC-Dre-028440	Danio rerio	71.05	0.00e+00	722.00
IUUC-Dno-029039	Dasypus novemcinctus	80.69	0.00e+00	929.00
IUUC-Dor-031043	Dipodomys ordii	89.66	4.00e-125	442.00
IUUC-Dme-032089	Drosophila melanogaster	46.83	7.00e-85	308.00
IUUC-Ete-033040	Echinops telfairi	63.37	0.00e+00	1230.00
IUUC-Eca-033449	Equus caballus	80.34	0.00e+00	922.00
IUUC-Eeu-034693	Erinaceus europaeus	88.36	2.00e-119	423.00
IUUC-Fca-035794	Felis catus	88.42	0.00e+00	840.00
IUUC-Fal-037322	Ficedula albicollis	94.10	0.00e+00	1911.00
IUUC-Gmo-038584	Gadus morhua	62.61	0.00e+00	671.00
IUUC-Gga-041188	Gallus gallus	89.96	0.00e+00	1018.00
IUUC-Gac-041850	Gasterosteus aculeatus	74.75	0.00e+00	739.00
IUUC-Ggo-045565	Gorilla gorilla	81.03	0.00e+00	922.00
IUUC-Hsa-046438	Homo sapiens	81.03	0.00e+00	922.00
IUUC-Itr-048883	Ictidomys tridecemlineatus	68.71	0.00e+00	1394.00
IUUC-Kpa-049321	Komagataella pastoris	33.24	1.00e-49	191.00
IUUC-Lch-050485	Latimeria chalumnae	83.64	0.00e+00	839.00
IUUC-Loc-052769	Lepisosteus oculatus	75.95	0.00e+00	770.00
IUUC-Laf-053432	Loxodonta africana	74.18	0.00e+00	867.00
IUUC-Mcc-055823	Macaca mulatta	80.52	0.00e+00	916.00
IUUC-Meu-056099	Macropus eugenii	92.57	5.00e-156	545.00
IUUC-Mla-059089	Melampsora laricipopulina	40.80	2.00e-72	267.00
IUUC-Mga-059739	Meleagris gallopavo	89.96	0.00e+00	1014.00
IUUC-Mvi-060559	Microbotryum violaceum	41.59	2.00e-78	287.00
IUUC-Mmr-061158	Microcebus murinus	79.83	0.00e+00	898.00
IUUC-Mdo-061801	Monodelphis domestica	84.06	0.00e+00	919.00
IUUC-Mmu-063665	Mus musculus	66.84	0.00e+00	1360.00
IUUC-Mpu-066738	Mustela putorius furo	69.31	0.00e+00	1420.00
IUUC-Mlu-067307	Myotis lucifugus	68.94	0.00e+00	1431.00
IUUC-Nfi-068410	Neosartorya fischeri	31.04	1.00e-51	198.00
IUUC-Nle-069314	Nomascus leucogenys	80.69	0.00e+00	919.00
IUUC-Opr-070378	Ochotona princeps	70.11	5.00e-131	461.00
IUUC-Ont-071545	Oreochromis niloticus	76.42	0.00e+00	760.00
IUUC-Oan-073537	Ornithorhynchus anatinus	81.46	0.00e+00	913.00
IUUC-Ocu-074193	Oryctolagus cuniculus	56.71	0.00e+00	1130.00
IUUC-Ola-086622	Oryzias latipes	75.97	0.00e+00	740.00
IUUC-Oga-088271	Otolemur garnettii	78.97	0.00e+00	897.00
IUUC-Oar-090431	Ovis aries	78.86	0.00e+00	879.00
IUUC-Ptr-091339	Pan troglodytes	70.76	0.00e+00	1479.00
IUUC-Pan-092266	Papio anubis	86.75	2.00e-168	584.00
IUUC-Psi-093187	Pelodiscus sinensis	66.74	6.00e-161	560.00
IUUC-Pma-094626	Petromyzon marinus	56.57	1.00e-141	495.00
IUUC-Pfo-096463	Poecilia formosa	75.20	0.00e+00	753.00
IUUC-Pab-097645	Pongo abelii	81.03	0.00e+00	921.00
IUUC-Pva-103222	Pteropus vampyrus	87.94	0.00e+00	696.00
IUUC-Pgr-103408	Puccinia graminis	36.31	1.00e-54	208.00
IUUC-Ptt-103699	Puccinia triticina	45.80	1.00e-67	251.00
IUUC-Pyt-104711	Pyrenophora triticirepentis	31.01	5.00e-54	206.00
IUUC-Rno-105510	Rattus norvegicus	66.20	0.00e+00	1362.00
IUUC-Sce-106166	Saccharomyces cerevisiae	35.54	8.00e-52	198.00
IUUC-Sha-106879	Sarcophilus harrisii	83.03	0.00e+00	914.00
IUUC-Sja-107836	Schizosaccharomyces japonicus	36.49	1.00e-51	197.00
IUUC-Sar-113019	Sorex araneus	66.34	0.00e+00	1338.00
IUUC-Sre-115031	Sporisorium reilianum	37.05	5.00e-70	259.00
IUUC-Ssc-116334	Sus scrofa	69.12	0.00e+00	1398.00
IUUC-Tru-117908	Takifugu rubripes	76.43	0.00e+00	748.00
IUUC-Tsy-118867	Tarsius syrichta	73.28	0.00e+00	806.00
IUUC-Tni-120206	Tetraodon nigroviridis	74.80	0.00e+00	729.00
IUUC-Tme-127144	Tuber melanosporum	40.28	7.00e-80	291.00
IUUC-Tbe-127877	Tupaia belangeri	90.20	2.00e-76	280.00
IUUC-Ttr-128580	Tursiops truncatus	79.31	0.00e+00	890.00
IUUC-Uma-129340	Ustilago maydis	37.85	7.00e-73	268.00
IUUC-Vpa-130541	Vicugna pacos	69.49	0.00e+00	1402.00
IUUC-Xtr-132161	Xenopus tropicalis	76.34	0.00e+00	798.00
IUUC-Xma-134271	Xiphophorus maculatus	74.59	0.00e+00	748.00
IUUC-Yli-134561	Yarrowia lipolytica	36.44	1.00e-62	234.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence