iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cja-019674

UUCD1 version

UUC-CaJ-00517

Ensembl Protein ID

ENSCJAP00000050212.1

UniProt Accession

F7FCE4; F7FCE4_CALJA

Genbank Protein ID

JAB09184.1; JAB22181.1; JAB28708.1; JAB39543.1; JAB48421.1

Protein Name

Polycomb group RING finger protein 2

Genbank Nucleotide ID

ACFV01098447; GAMS01000955; GAMR01005224; GAMQ01002308; GAMP01004334

Gene Name

PCGF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000008215.3	ENSCJAT00000059023.1	ENSCJAP00000050212.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.20e-06	28.2	18	56
ULD/UDP/UFD/RAWUL	1.60e-28	100.0	131	228

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           Ca+C   f d + ++ C H f+++C+ ++        ++ +CP C
   Q: 18   CALCGGYFIDATTIVECLHSFCKTCIVRY------LETNKYCPMC 56
           ********999999***************......********** PP

ULD/UDP/UFD/RAWUL

   S: 1    islsLeplesnkakddsk............lkkkylrcsarltVkhlkkflaeklklsssyevdllcedevLednetLeeikyifiwkk 77
           +sls+e++e ++++d++k            +  ++lrc+a++tV+hl kfl++k++++s+y+v++l+ede+L++++tL++i+yi+ w++
   Q: 131  VSLSIEFYEGARERDEKKgplengdgdkekTGVRFLRCPAAMTVMHLAKFLRNKMDVPSKYKVEVLYEDEPLKEYYTLMDIAYIYPWRR 219
           58899999999999988899999999999999********************************************************* PP
   S: 78   egpLvLqYr 86
           +gpL+L+Yr
   Q: 220  NGPLPLKYR 228
           ********9 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MHRTTRIKIT ELNPHLMCAL CGGYFIDATT IVECLHSFCK TCIVRYLETN KYCPMCDVQV 60
HKTRPLLSIR SDKTLQDIVY KLVPGLFKDE MKRRRDFYAA YPLTEVPNGS NEDRGEVLEQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTCCCCTCC CGCCGCCGGG GCGAGCGACA CGGCTGCGGC CCCCCTCCCC TCCCTTCCCT 60
CCCTCCCTCC CATCCCCCCC TCCCCGAGAC CCACCGGACC CCGAACACAG GTAAGCGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032443--RAWUL
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF16207--RAWUL

SMART

SM00184--RING

Gene Ontology

GO:0016604--C:nuclear body
GO:0035102--C:PRC1 complex
GO:0001739--C:sex chromatin
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0009952--P:anterior/posterior pattern specification
GO:0070301--P:cellular response to hydrogen peroxide
GO:0048704--P:embryonic skeletal system morphogenesis
GO:0016573--P:histone acetylation
GO:0001701--P:in utero embryonic development
GO:2001234--P:negative regulation of apoptotic signaling pathway
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002051	Ailuropoda melanoleuca	94.48	7.00e-156	543.00
IUUC-Aca-004230	Anolis carolinensis	75.83	9.00e-141	493.00
IUUC-Bta-013298	Bos taurus	96.51	2.00e-163	567.00
IUUC-Bol-015090	Brassica oleracea	36.73	3.00e-13	69.70
IUUC-Cfa-020865	Canis familiaris	89.94	9.00e-147	512.00
IUUC-Cpo-022149	Cavia porcellus	94.48	2.00e-160	557.00
IUUC-Csa-024153	Chlorocebus sabaeus	99.42	6.00e-167	579.00
IUUC-Dno-029941	Dasypus novemcinctus	94.48	1.00e-156	545.00
IUUC-Dor-030557	Dipodomys ordii	96.80	3.00e-161	560.00
IUUC-Eca-033878	Equus caballus	97.91	3.00e-153	534.00
IUUC-Eeu-035039	Erinaceus europaeus	92.15	6.00e-150	523.00
IUUC-Fca-036531	Felis catus	90.14	6.00e-142	496.00
IUUC-Gga-040311	Gallus gallus	84.47	6.00e-130	456.00
IUUC-Ggo-045132	Gorilla gorilla	99.13	6.00e-167	579.00
IUUC-Hsa-045703	Homo sapiens	98.84	2.00e-169	588.00
IUUC-Itr-048008	Ictidomys tridecemlineatus	98.26	1.00e-164	572.00
IUUC-Lch-050240	Latimeria chalumnae	73.76	2.00e-129	454.00
IUUC-Laf-053589	Loxodonta africana	97.96	2.00e-162	565.00
IUUC-Mcc-055228	Macaca mulatta	99.13	2.00e-165	575.00
IUUC-Meu-056268	Macropus eugenii	81.10	2.00e-133	468.00
IUUC-Mga-059555	Meleagris gallopavo	77.78	1.00e-83	302.00
IUUC-Mmr-060605	Microcebus murinus	97.96	8.00e-164	569.00
IUUC-Mdo-061947	Monodelphis domestica	95.06	3.00e-147	514.00
IUUC-Mmu-063845	Mus musculus	95.91	3.00e-160	557.00
IUUC-Mpu-066061	Mustela putorius furo	96.80	7.00e-163	566.00
IUUC-Mlu-067426	Myotis lucifugus	90.77	3.00e-143	500.00
IUUC-Nle-069772	Nomascus leucogenys	91.72	4.00e-158	550.00
IUUC-Ocu-074159	Oryctolagus cuniculus	82.15	5.00e-144	503.00
IUUC-Oga-088514	Otolemur garnettii	97.97	9.00e-165	572.00
IUUC-Oar-090406	Ovis aries	91.57	3.00e-163	566.00
IUUC-Ptr-091467	Pan troglodytes	98.84	2.00e-166	577.00
IUUC-Psi-093492	Pelodiscus sinensis	82.66	5.00e-154	536.00
IUUC-Pab-098045	Pongo abelii	93.08	3.00e-145	507.00
IUUC-Pca-100551	Procavia capensis	97.09	8.00e-164	569.00
IUUC-Pva-102686	Pteropus vampyrus	97.38	5.00e-164	570.00
IUUC-Rno-105679	Rattus norvegicus	95.91	1.00e-160	558.00
IUUC-Sha-107443	Sarcophilus harrisii	73.85	6.00e-135	473.00
IUUC-Smo-109158	Selaginella moellendorffii	50.00	2.00e-11	64.30
IUUC-Ssc-115591	Sus scrofa	77.81	2.00e-138	484.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence