iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-051808

Ensembl Protein ID

ENSLOCP00000017596.1

UniProt Accession

W5NAD7; W5NAD7_LEPOC

Genbank Protein ID

ENSLOCP00000017596

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01040429

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000014293.1	ENSLOCT00000017628.1	ENSLOCP00000017596.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.00e-91	307.8	64	396

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgy 87
           +G++N+gNtC++N+vLQcLs++ +lr+ +l+ ++ +++     + +  el++++ ++++ lw  + ++av p ++++ +++  ++f++y
   Q: 64   VGIHNVGNTCFLNAVLQCLSHTLPLRDHCLRqRYLQDMG----TRKPPELMNAFSQVLSDLWaPEGSTAVHPGRFYTLFRESVPNFNTY 148
           69*****************************44555554....56779**************888899********************* PP
   S: 88   eqqDaqEflaflldqleeelkk..eknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepf 169
           +qqDaqEfl+flld+l++e+++   ++ p   ++e+++++l  e      +++  ++ +s i++lF gql+s++ c  c+++s++++ f
   Q: 149  SQQDAQEFLRFLLDRLHSEVNRhsPSSAPSPALTESKHTQLRVEdraahLWNRYLERDNSRIVELFSGQLRSSLCCSVCGHQSTTFDVF 237
           ********************88774444444455555444444455666999************************************* PP
   S: 170  ldlslpvpgkeetk.keslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpl 257
           +dlslp+p+++ +    sl+dcLe f++ee l++en+  c++c + +e++kkl+++++P++++lhLkRf    ++ s +k + +v+fpl
   Q: 238  CDLSLPIPKRSVSGgIVSLKDCLELFSQEEALDSENAPMCDRCGRCTESTKKLSVQRFPRIIVLHLKRF--AASRFSISKSTVSVSFPL 324
           ********999754156****************************************************..55568999********** PP
   S: 258  e.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
           + Ldl ++ ++ +     ++ Y+L+av++HsG+++ GHY+ay+ + + +W++++Ds+V++ +e++ ++   ++aY+lfY+
   Q: 325  RhLDLGQYGAQGTG----RVLYNLYAVCNHSGTVNMGHYTAYCLE-QAGWYCYNDSRVSPASESQLQS---NQAYLLFYE 396
           **********9443....79*************************.788*******************...********8 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

VARRAAAVME DSCQALCRSL ATQSAVQQEG PDISQSVLYS SLMGLLLVAD NEQEASLTLG 60
SGRVGIHNVG NTCFLNAVLQ CLSHTLPLRD HCLRQRYLQD MGTRKPPELM NAFSQVLSDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGAAACGCA AAGCTTTTGC GACGGAGTGA CCGGCGCCCC GGCTGGGTCT GCAGACTGTC 60
CAGGAGACCG CCGCGGCGGT GAGAGTGACG CGCCGGATCT CCTCTCCTGA GCGGCTGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0021551--P:central nervous system morphogenesis
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001858	Ailuropoda melanoleuca	55.00	5.00e-115	407.00
IUUC-Aca-004612	Anolis carolinensis	51.69	2.00e-105	375.00
IUUC-Ame-011548	Astyanax mexicanus	61.44	2.00e-144	505.00
IUUC-Bta-012626	Bos taurus	55.28	7.00e-116	410.00
IUUC-Bol-015281	Brassica oleracea	37.09	1.00e-51	197.00
IUUC-Bra-017228	Brassica rapa	36.20	2.00e-49	190.00
IUUC-Cja-018853	Callithrix jacchus	56.08	9.00e-116	410.00
IUUC-Cfa-021167	Canis familiaris	55.25	9.00e-114	404.00
IUUC-Cpo-021305	Cavia porcellus	55.93	3.00e-115	408.00
IUUC-Csa-023454	Chlorocebus sabaeus	55.80	2.00e-115	409.00
IUUC-Cho-024836	Choloepus hoffmanni	61.08	2.00e-64	239.00
IUUC-Dre-028454	Danio rerio	63.21	2.00e-148	518.00
IUUC-Dor-031053	Dipodomys ordii	56.08	3.00e-115	409.00
IUUC-Ete-032416	Echinops telfairi	54.96	1.00e-82	300.00
IUUC-Eca-033817	Equus caballus	56.08	3.00e-116	412.00
IUUC-Fca-036400	Felis catus	54.85	2.00e-113	402.00
IUUC-Gmo-038926	Gadus morhua	63.93	2.00e-133	468.00
IUUC-Gac-041331	Gasterosteus aculeatus	62.89	4.00e-140	491.00
IUUC-Ggo-045174	Gorilla gorilla	55.80	2.00e-115	409.00
IUUC-Hsa-046443	Homo sapiens	55.80	2.00e-115	409.00
IUUC-Itr-048329	Ictidomys tridecemlineatus	54.82	6.00e-113	401.00
IUUC-Laf-053730	Loxodonta africana	55.89	4.00e-115	408.00
IUUC-Mcc-055541	Macaca mulatta	55.80	2.00e-115	409.00
IUUC-Meu-056279	Macropus eugenii	55.12	3.00e-115	409.00
IUUC-Mmr-060913	Microcebus murinus	55.00	6.00e-115	407.00
IUUC-Mdo-061807	Monodelphis domestica	55.40	2.00e-109	390.00
IUUC-Mmu-063599	Mus musculus	54.92	4.00e-113	401.00
IUUC-Mpu-066329	Mustela putorius furo	55.25	9.00e-114	404.00
IUUC-Mlu-067359	Myotis lucifugus	53.35	2.00e-94	339.00
IUUC-Nle-070084	Nomascus leucogenys	54.72	1.00e-111	397.00
IUUC-Opr-071096	Ochotona princeps	54.55	1.00e-111	396.00
IUUC-Ocu-074228	Oryctolagus cuniculus	53.99	5.00e-112	397.00
IUUC-Ola-086684	Oryzias latipes	62.70	1.00e-135	475.00
IUUC-Oar-090226	Ovis aries	53.82	2.00e-88	320.00
IUUC-Ptr-091522	Pan troglodytes	55.80	2.00e-115	409.00
IUUC-Pan-091954	Papio anubis	55.25	3.00e-113	402.00
IUUC-Psi-093216	Pelodiscus sinensis	55.68	1.00e-117	417.00
IUUC-Pfo-096257	Poecilia formosa	62.18	6.00e-142	496.00
IUUC-Pab-098691	Pongo abelii	55.80	2.00e-115	409.00
IUUC-Pca-101133	Procavia capensis	48.90	6.00e-96	344.00
IUUC-Pva-102681	Pteropus vampyrus	54.17	1.00e-109	390.00
IUUC-Rno-105132	Rattus norvegicus	54.72	2.00e-114	406.00
IUUC-Sha-107145	Sarcophilus harrisii	55.88	1.00e-108	386.00
IUUC-Smo-109021	Selaginella moellendorffii	34.65	4.00e-46	178.00
IUUC-Ssc-115586	Sus scrofa	55.00	7.00e-114	404.00
IUUC-Tni-120746	Tetraodon nigroviridis	60.36	2.00e-124	438.00
IUUC-Tbe-127465	Tupaia belangeri	61.65	1.00e-76	280.00
IUUC-Ttr-128274	Tursiops truncatus	52.50	4.00e-105	375.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence