iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-068975

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01091714

Gene Name

USP21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000019348.1	ENSNLET00000024373.1	ENSNLEP00000023185.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	8.90e-87	291.4	212	556

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgy 87
           +Gl+NlgNtC++N+vLQcLs++++lr+++l+  + ++++     ++ +el+++++++  +lw  ++ +av+p+++ ++++k+ ++fsgy
   Q: 212  VGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRrDFWQEVPG---GGRAQELTEAFADVTGALWhPDSCEAVNPTRFRAVFQKYVPSFSGY 297
           6******************************555555555...689****************888899********************* PP
   S: 88   eqqDaqEflaflldqleeelkk..................eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikcle 158
           +qqDaqEfl+ l+++l+ e+++                  ++     ee e ++ ++ +  +++  ++++s  +dlF gqlks +kc++
   Q: 298  SQQDAQEFLKLLMERLHLEINRrgrrappilangpvpsppRRGGALLEEPEFSDDDRANLMWKRYLEREDSKTVDLFVGQLKSCLKCQA 386
           ********************9999999999999988888766677777777777777888***************************** PP
   S: 159  cdnvssreepfldlslpvpgkeet.kkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksr 246
           c+ +s+++e f+dlslp+p+k     k sl+dc++ f keeele+en+  c++c++k++++kkl+++++P++L+lhL+Rf  s +++s 
   Q: 387  CGYRSTTFEVFCDLSLPIPKKGFAgGKVSLRDCFNLFPKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRF--SASRGSI 473
           *******************887541456****************************************************..5566899 PP
   S: 247  ekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlf 334
           +k +  v++pl+ L+l  f +++      +  Y+L+a ++HsGs++ GHY+a+++  + +W  ++Ds+V++v+e++v +   s++Yv f
   Q: 474  KKSSVGVDLPLQrLSLGDFASDKAG----SPVYQLYALCNHSGSAHYGHYTALCRC-QTGWHVYNDSRVSPVSENQVAS---SEGYVPF 554
           9*********999*******99543....78*************************.777*******************...******* PP
   S: 335  Yk 336
           Y+
   Q: 555  YQ 556
           *8 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MPQASEHRLG RTREPPVNIQ PRVGSKLPFA PRARSKERRN PASGPNPMLR PLPPRPGPPD 60
ERLKKLELGR GRTSGPRPRG PLRADHGVPL PGSPPPTVAL PLSSRTNLAR SKSVSSGDLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCCAGG CCTCTGAGCA CCGCCTGGGC CGGACCCGAG AGCCACCTGT TAATATCCAG 60
CCCCGAGTGG GATCCAAGCT ACCATTTGCC CCCAGGGCCC GCAGCAAGGA GCGCAGAAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0019784--F:NEDD8-specific protease activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

nle:100607886

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001858	Ailuropoda melanoleuca	94.34	0.00e+00	973.00
IUUC-Bta-012626	Bos taurus	95.22	0.00e+00	959.00
IUUC-Cja-018853	Callithrix jacchus	96.81	0.00e+00	1012.00
IUUC-Cfa-021167	Canis familiaris	94.87	0.00e+00	966.00
IUUC-Cpo-021305	Cavia porcellus	93.82	0.00e+00	930.00
IUUC-Csa-023454	Chlorocebus sabaeus	97.70	0.00e+00	1022.00
IUUC-Dor-031053	Dipodomys ordii	94.51	0.00e+00	1019.00
IUUC-Ete-032416	Echinops telfairi	93.26	8.00e-140	490.00
IUUC-Eca-033817	Equus caballus	93.98	0.00e+00	982.00
IUUC-Fca-036400	Felis catus	94.18	0.00e+00	960.00
IUUC-Ggo-045174	Gorilla gorilla	97.70	0.00e+00	1022.00
IUUC-Hsa-046443	Homo sapiens	97.52	0.00e+00	1015.00
IUUC-Itr-048329	Ictidomys tridecemlineatus	94.54	0.00e+00	982.00
IUUC-Laf-053730	Loxodonta africana	92.78	0.00e+00	989.00
IUUC-Mcc-055541	Macaca mulatta	97.70	0.00e+00	1022.00
IUUC-Meu-056279	Macropus eugenii	88.16	0.00e+00	935.00
IUUC-Mdo-061807	Monodelphis domestica	88.16	0.00e+00	868.00
IUUC-Mmu-063599	Mus musculus	93.67	0.00e+00	934.00
IUUC-Mpu-066329	Mustela putorius furo	95.22	0.00e+00	967.00
IUUC-Mlu-067359	Myotis lucifugus	91.41	0.00e+00	865.00
IUUC-Opr-071096	Ochotona princeps	91.50	0.00e+00	926.00
IUUC-Ocu-074228	Oryctolagus cuniculus	94.89	0.00e+00	961.00
IUUC-Ola-086684	Oryzias latipes	49.58	4.00e-98	351.00
IUUC-Oar-090226	Ovis aries	91.40	0.00e+00	750.00
IUUC-Ptr-091522	Pan troglodytes	97.70	0.00e+00	1022.00
IUUC-Pan-091954	Papio anubis	97.35	0.00e+00	1014.00
IUUC-Pab-098691	Pongo abelii	97.52	0.00e+00	1021.00
IUUC-Pca-101133	Procavia capensis	86.55	0.00e+00	922.00
IUUC-Pva-102681	Pteropus vampyrus	91.15	0.00e+00	905.00
IUUC-Rno-105132	Rattus norvegicus	94.51	0.00e+00	959.00
IUUC-Sha-107145	Sarcophilus harrisii	88.08	0.00e+00	855.00
IUUC-Ssc-115586	Sus scrofa	95.40	0.00e+00	948.00
IUUC-Tgu-117491	Taeniopygia guttata	80.25	9.00e-111	392.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence