iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-044669

Ensembl Protein ID

ENSGGOP00000024279.1

UniProt Accession

G3S867; G3S867_GORGO

Protein Name

Uncharacterized protein

Gene Name

EML2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000015482.2	ENSGGOT00000031136.1	ENSGGOP00000024279.1
ENSGGOG00000015482.2	ENSGGOT00000015539.2	ENSGGOP00000015107.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-16	60.0	412	441

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtcla.fsd.tllvsGsdDgtikvWD 29
           H ++v++l+ + d tl++ G++D  + +W 
   Q: 412  HDGGVFGLCaLRDgTLVSGGGRDRRVVLWG 441
           999****97367746655588********6 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

EECADGLESC XQRLQLQEDE LAVLKAALAD ALRRLRACEE QGAALRARGT PKGRAPPRTP 60
LNGSGPPRRV GGYATSPSSP KKEATSGRSS VRRYLSPERL ASVRREDPRS RTTSSSSNCS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGAGTGTG CGGATGGGTT GGAGAGCTGT GNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 60
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0072686--C:mitotic spindle
GO:0031115--P:negative regulation of microtubule polymerization
GO:0010968--P:regulation of microtubule nucleation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002155	Ailuropoda melanoleuca	92.26	0.00e+00	1394.00
IUUC-Aca-005316	Anolis carolinensis	75.00	0.00e+00	1117.00
IUUC-Bta-013267	Bos taurus	92.27	0.00e+00	1394.00
IUUC-Cja-019146	Callithrix jacchus	91.39	0.00e+00	1229.00
IUUC-Cfa-020267	Canis familiaris	93.19	0.00e+00	1408.00
IUUC-Dno-028961	Dasypus novemcinctus	90.24	0.00e+00	1327.00
IUUC-Eca-033785	Equus caballus	92.72	0.00e+00	1382.00
IUUC-Eeu-035302	Erinaceus europaeus	95.11	0.00e+00	724.00
IUUC-Fca-036170	Felis catus	92.12	0.00e+00	1382.00
IUUC-Hsa-046141	Homo sapiens	95.86	0.00e+00	1439.00
IUUC-Itr-048788	Ictidomys tridecemlineatus	91.48	0.00e+00	1377.00
IUUC-Laf-054137	Loxodonta africana	89.04	0.00e+00	1165.00
IUUC-Mcc-055780	Macaca mulatta	96.70	0.00e+00	1198.00
IUUC-Meu-056664	Macropus eugenii	82.30	0.00e+00	1105.00
IUUC-Mmr-060853	Microcebus murinus	92.65	0.00e+00	1394.00
IUUC-Mdo-062224	Monodelphis domestica	83.01	0.00e+00	1092.00
IUUC-Mmu-063860	Mus musculus	91.57	0.00e+00	1382.00
IUUC-Mpu-066043	Mustela putorius furo	92.64	0.00e+00	1393.00
IUUC-Mlu-067125	Myotis lucifugus	73.45	0.00e+00	982.00
IUUC-Nle-069618	Nomascus leucogenys	87.03	0.00e+00	1267.00
IUUC-Opr-070228	Ochotona princeps	84.47	0.00e+00	1104.00
IUUC-Ocu-074087	Oryctolagus cuniculus	81.85	0.00e+00	850.00
IUUC-Oga-088048	Otolemur garnettii	90.12	0.00e+00	1353.00
IUUC-Oar-089907	Ovis aries	94.11	0.00e+00	1222.00
IUUC-Pan-092082	Papio anubis	95.06	0.00e+00	1431.00
IUUC-Pab-097619	Pongo abelii	97.23	0.00e+00	1293.00
IUUC-Pca-101070	Procavia capensis	83.39	0.00e+00	1076.00
IUUC-Pva-102957	Pteropus vampyrus	89.58	0.00e+00	1177.00
IUUC-Rno-105074	Rattus norvegicus	92.38	0.00e+00	1215.00
IUUC-Sha-106692	Sarcophilus harrisii	81.62	0.00e+00	1199.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence