iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-116912

Ensembl Protein ID

ENSTGUP00000006771.1

UniProt Accession

H0Z868; H0Z868_TAEGU

Genbank Protein ID

ENSTGUP00000006771

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

ABQF01028372

Gene Name

HCK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000006558.1	ENSTGUT00000006839.1	ENSTGUP00000006771.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.20e-15	56.2	49	102

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v +lydyea n ++L+++kG+ ++v+   e++++W+++ +  +g +G++P+n+v++
   Q: 49   VVLALYDYEAMNAGDLSFQKGERMKVL---EKSGEWWQARSLVTGHEGFIPSNYVAQ 102
           6889***********************...*************************86 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MGCVRSKQAG VQEKMIKTDP DPDPGPTIQQ GHYVRDPTAT NKRGLGDSVV LALYDYEAMN 60
AGDLSFQKGE RMKVLEKSGE WWQARSLVTG HEGFIPSNYV AQENSLETEE WFFKDISRKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGTTGTG TGAGGTCAAA GCAAGCTGGT GTCCAAGAGA AGATGATAAA AACTGATCCT 60
GACCCTGATC CTGGCCCCAC CATCCAGCAG GGCCACTATG TGAGGGACCC CACAGCCACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001284	Ailuropoda melanoleuca	78.19	0.00e+00	802.00
IUUC-Apl-003285	Anas platyrhynchos	84.87	0.00e+00	889.00
IUUC-Aca-004724	Anolis carolinensis	78.04	0.00e+00	799.00
IUUC-Ame-011954	Astyanax mexicanus	74.46	0.00e+00	758.00
IUUC-Bta-013060	Bos taurus	78.11	0.00e+00	802.00
IUUC-Bdi-014122	Brachypodium distachyon	31.64	2.00e-21	97.80
IUUC-Cja-019817	Callithrix jacchus	77.45	0.00e+00	793.00
IUUC-Cfa-020511	Canis familiaris	78.30	0.00e+00	804.00
IUUC-Cpo-022538	Cavia porcellus	76.33	0.00e+00	781.00
IUUC-Csa-024143	Chlorocebus sabaeus	78.39	0.00e+00	797.00
IUUC-Dre-028157	Danio rerio	73.83	0.00e+00	781.00
IUUC-Dno-029761	Dasypus novemcinctus	76.74	0.00e+00	788.00
IUUC-Dor-030892	Dipodomys ordii	65.20	0.00e+00	668.00
IUUC-Eca-034090	Equus caballus	76.13	0.00e+00	774.00
IUUC-Fca-035937	Felis catus	76.77	0.00e+00	773.00
IUUC-Fal-036624	Ficedula albicollis	93.89	0.00e+00	989.00
IUUC-Gmo-039009	Gadus morhua	72.49	0.00e+00	754.00
IUUC-Gga-040296	Gallus gallus	82.35	0.00e+00	857.00
IUUC-Gac-042362	Gasterosteus aculeatus	74.21	0.00e+00	785.00
IUUC-Ggo-044570	Gorilla gorilla	77.65	0.00e+00	795.00
IUUC-Hsa-046378	Homo sapiens	78.22	0.00e+00	797.00
IUUC-Hvu-047818	Hordeum vulgare	31.52	1.00e-21	97.80
IUUC-Itr-048695	Ictidomys tridecemlineatus	76.94	0.00e+00	790.00
IUUC-Loc-052904	Lepisosteus oculatus	76.67	0.00e+00	811.00
IUUC-Laf-053654	Loxodonta africana	78.85	0.00e+00	806.00
IUUC-Mcc-055317	Macaca mulatta	78.39	0.00e+00	802.00
IUUC-Meu-056879	Macropus eugenii	68.07	0.00e+00	665.00
IUUC-Mga-060194	Meleagris gallopavo	84.89	0.00e+00	808.00
IUUC-Mmr-061510	Microcebus murinus	76.57	0.00e+00	791.00
IUUC-Mdo-062035	Monodelphis domestica	77.17	0.00e+00	798.00
IUUC-Mmu-064037	Mus musculus	76.77	0.00e+00	798.00
IUUC-Mac-064532	Musa acuminata	33.18	2.00e-20	94.40
IUUC-Mpu-066874	Mustela putorius furo	78.74	0.00e+00	810.00
IUUC-Mlu-068202	Myotis lucifugus	75.15	0.00e+00	771.00
IUUC-Nle-069222	Nomascus leucogenys	78.15	0.00e+00	801.00
IUUC-Opr-070705	Ochotona princeps	75.79	0.00e+00	780.00
IUUC-Ont-072347	Oreochromis niloticus	81.66	0.00e+00	756.00
IUUC-Ocu-074490	Oryctolagus cuniculus	76.13	0.00e+00	787.00
IUUC-Oba-075998	Oryza barthii	30.94	4.00e-23	103.00
IUUC-Obr-076585	Oryza brachyantha	30.71	3.00e-21	97.10
IUUC-Ogl-077452	Oryza glaberrima	30.74	3.00e-23	103.00
IUUC-Ogu-078147	Oryza glumaepatula	30.94	4.00e-23	103.00
IUUC-Oin-079983	Oryza indica	30.94	4.00e-23	102.00
IUUC-Olo-081004	Oryza longistaminata	30.94	9.00e-23	101.00
IUUC-Oni-082859	Oryza nivara	30.94	4.00e-23	102.00
IUUC-Opu-083690	Oryza punctata	30.74	2.00e-22	100.00
IUUC-Oru-084532	Oryza rufipogon	30.94	5.00e-23	102.00
IUUC-Osa-085517	Oryza sativa	30.94	5.00e-23	102.00
IUUC-Ola-086521	Oryzias latipes	80.67	0.00e+00	770.00
IUUC-Oga-088153	Otolemur garnettii	77.18	0.00e+00	793.00
IUUC-Oar-090184	Ovis aries	77.25	0.00e+00	793.00
IUUC-Ptr-090505	Pan troglodytes	74.12	0.00e+00	743.00
IUUC-Pan-092260	Papio anubis	78.59	0.00e+00	803.00
IUUC-Pma-094311	Petromyzon marinus	70.45	0.00e+00	695.00
IUUC-Pfo-096566	Poecilia formosa	74.46	0.00e+00	788.00
IUUC-Pva-103021	Pteropus vampyrus	77.76	0.00e+00	799.00
IUUC-Rno-105309	Rattus norvegicus	76.97	0.00e+00	798.00
IUUC-Sha-107099	Sarcophilus harrisii	76.52	0.00e+00	793.00
IUUC-Sit-110451	Setaria italica	30.94	5.00e-24	105.00
IUUC-Sly-111528	Solanum lycopersicum	32.73	1.00e-22	101.00
IUUC-Stu-112331	Solanum tuberosum	30.16	4.00e-22	99.80
IUUC-Sbi-114267	Sorghum bicolor	30.50	1.00e-23	104.00
IUUC-Ssc-115624	Sus scrofa	69.28	0.00e+00	683.00
IUUC-Tru-118449	Takifugu rubripes	81.17	0.00e+00	759.00
IUUC-Tae-125706	Triticum aestivum	31.88	1.00e-22	101.00
IUUC-Tur-126322	Triticum urartu	31.52	4.00e-22	99.40
IUUC-Tbe-128144	Tupaia belangeri	75.33	0.00e+00	686.00
IUUC-Vvi-131372	Vitis vinifera	29.89	5.00e-22	99.40
IUUC-Xtr-132224	Xenopus tropicalis	70.16	0.00e+00	675.00
IUUC-Xma-133902	Xiphophorus maculatus	75.35	0.00e+00	788.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence