iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020628

Ensembl Protein ID

ENSCAFP00000006002.3

UniProt Accession

F1PR68; F1PR68_CANLF

Genbank Protein ID

ENSCAFP00000006002

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03010782

Gene Name

ITSN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000004019.3	ENSCAFT00000006481.3	ENSCAFP00000006002.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.20e-60	199.9	1131	1183

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v+++ydy a+n+deL++ kG  + v+  ++ d +W++g  e +g  GlfP+n+v+ 
   Q: 1131 QVIAMYDYAANNEDELNFSKGQLINVL--NKDDPDWWQG--EINGVTGLFPSNYVKM 1183
           6899***********************..8889******..9*************85 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MMAQFPTAMN GGPNMWAITS EERTKHDKQF DNLKPSGGYI TGDQARTFFL QSGLPAPVLA 60
EIWALSDLNK DGKMDQQEFS IAMKLIKLKL QGQQLPVVLP PIMKQPPMFS PLISARFGMG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGAGA GCTAGCCAGG AAAATTCAGT ACCATGATGG CTCAGTTTCC CACAGCTATG 60
AATGGTAAGC CGCTTTGTGC TTATGGCAAG TTAAAGAGGT TATGGGGGGG TTTTGGCTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR027029--Intersectin-2
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005813--C:centrosome
GO:0070062--C:extracellular exosome
GO:0005509--F:calcium ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0006897--P:endocytosis
GO:1903861--P:positive regulation of dendrite extension
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001455	Ailuropoda melanoleuca	97.80	0.00e+00	2264.00
IUUC-Apl-004205	Anas platyrhynchos	79.93	0.00e+00	2449.00
IUUC-Aca-004287	Anolis carolinensis	80.63	0.00e+00	1673.00
IUUC-Ame-011759	Astyanax mexicanus	64.40	0.00e+00	1241.00
IUUC-Bta-013248	Bos taurus	92.65	0.00e+00	2119.00
IUUC-Cel-018490	Caenorhabditis elegans	25.78	2.00e-52	201.00
IUUC-Cpo-022427	Cavia porcellus	80.88	0.00e+00	2619.00
IUUC-Csa-023122	Chlorocebus sabaeus	91.36	0.00e+00	2166.00
IUUC-Dre-027849	Danio rerio	65.06	0.00e+00	1207.00
IUUC-Dno-029419	Dasypus novemcinctus	94.37	0.00e+00	2203.00
IUUC-Dor-030504	Dipodomys ordii	77.98	0.00e+00	1744.00
IUUC-Dme-032099	Drosophila melanogaster	32.01	2.00e-56	214.00
IUUC-Eca-034196	Equus caballus	92.82	0.00e+00	2111.00
IUUC-Eeu-034972	Erinaceus europaeus	69.08	0.00e+00	642.00
IUUC-Fca-035757	Felis catus	96.08	0.00e+00	2245.00
IUUC-Fal-037531	Ficedula albicollis	87.74	0.00e+00	1722.00
IUUC-Gga-041012	Gallus gallus	79.27	0.00e+00	1888.00
IUUC-Gac-041320	Gasterosteus aculeatus	49.18	0.00e+00	1475.00
IUUC-Ggo-045405	Gorilla gorilla	90.68	0.00e+00	2695.00
IUUC-Hsa-046833	Homo sapiens	92.26	0.00e+00	2152.00
IUUC-Lch-050094	Latimeria chalumnae	74.27	0.00e+00	1692.00
IUUC-Loc-052646	Lepisosteus oculatus	70.88	0.00e+00	1437.00
IUUC-Laf-053798	Loxodonta africana	87.62	0.00e+00	1442.00
IUUC-Mcc-054709	Macaca mulatta	91.93	0.00e+00	2173.00
IUUC-Meu-056396	Macropus eugenii	80.99	0.00e+00	1538.00
IUUC-Mga-059997	Meleagris gallopavo	83.67	0.00e+00	2019.00
IUUC-Mvi-060268	Microbotryum violaceum	30.33	8.00e-46	180.00
IUUC-Mmr-060891	Microcebus murinus	92.08	0.00e+00	2190.00
IUUC-Mmu-064226	Mus musculus	87.09	0.00e+00	2153.00
IUUC-Mpu-066431	Mustela putorius furo	94.29	0.00e+00	2234.00
IUUC-Mlu-068190	Myotis lucifugus	94.45	0.00e+00	2201.00
IUUC-Nle-070116	Nomascus leucogenys	92.07	0.00e+00	1721.00
IUUC-Opr-070815	Ochotona princeps	78.55	0.00e+00	1753.00
IUUC-Ont-072464	Oreochromis niloticus	64.70	0.00e+00	1224.00
IUUC-Ola-086482	Oryzias latipes	60.98	0.00e+00	1224.00
IUUC-Oga-088449	Otolemur garnettii	90.37	0.00e+00	2105.00
IUUC-Oar-090275	Ovis aries	92.98	0.00e+00	2157.00
IUUC-Ptr-091667	Pan troglodytes	91.69	0.00e+00	2134.00
IUUC-Pan-091723	Papio anubis	88.26	0.00e+00	1848.00
IUUC-Psi-093136	Pelodiscus sinensis	82.17	0.00e+00	1938.00
IUUC-Pab-098755	Pongo abelii	89.49	0.00e+00	2070.00
IUUC-Pca-101134	Procavia capensis	86.41	0.00e+00	1496.00
IUUC-Pva-102433	Pteropus vampyrus	84.65	0.00e+00	1953.00
IUUC-Pgr-103473	Puccinia graminis	30.68	4.00e-38	154.00
IUUC-Ptt-103973	Puccinia triticina	25.00	3.00e-26	115.00
IUUC-Rno-105691	Rattus norvegicus	91.84	0.00e+00	2212.00
IUUC-Sar-112978	Sorex araneus	91.84	0.00e+00	1443.00
IUUC-Sre-115028	Sporisorium reilianum	37.20	4.00e-33	138.00
IUUC-Ssc-115562	Sus scrofa	86.92	0.00e+00	1981.00
IUUC-Tgu-116758	Taeniopygia guttata	83.37	0.00e+00	2013.00
IUUC-Tni-119958	Tetraodon nigroviridis	55.80	0.00e+00	1691.00
IUUC-Tbe-127477	Tupaia belangeri	91.25	0.00e+00	754.00
IUUC-Ttr-129196	Tursiops truncatus	92.02	0.00e+00	2102.00
IUUC-Vpa-130035	Vicugna pacos	82.01	0.00e+00	640.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence