iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090367

Ensembl Protein ID

ENSOARP00000011297.1

UniProt Accession

W5PLH4; W5PLH4_SHEEP

Genbank Protein ID

ENSOARP00000011297

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01078318

Gene Name

BIRC6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000010515.1	ENSOART00000011457.1	ENSOARP00000011297.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.60e-34	117.7	4581	4737

Active Site

Position(s)	Description	Evidence
4670	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    Rlkkelkelekdpp....egisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltk.....ifhPnvyen 78
           Rl++e+ +l+++ p    +++++++++e  l+ ++vli+Gp+dtpY++g+F+++++fp+dYP++PP v+++t+     +f+Pn+y++
   Q: 4581 RLAQEAVTLSTSLPlsssSSVFVRCDEE-RLDIMKVLITGPADTPYANGCFEFDVYFPQDYPSSPPLVNLETTgghsvRFNPNLYND 4666
           8999999999998877768899999999.6********************************************************* PP
   S: 79   GkvClsilk.....eeekWsp.alsvesvllsiqsll..aepnpesplneeaa...ellkknreeykkkvre 139
           GkvClsil+     +eekW+p ++s+ +vl+s+qsl+  aep++++p +e+++   + ++++re y+ ++r+
   Q: 4667 GKVCLSILNtwhgrPEEKWNPqTSSFLQVLVSVQSLIlvAEPYFNEPGYERSRgtpSGTQSSRE-YDGNIRQ 4737
           ********7788889******8899***********999***********99866555666655.9998875 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MVTGGGAAPP GTVTEPLPSV IVLSAGRKMA AAAAAASGPG LRDGCMALRP HGLHSLSYHP 60
ALNAILAVTS RGTIKVIDGT SGATLQASAL SAKPGGQVKC QYISAVDKVI FVDDYAVGCR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGACTG GTGGTGGTGC TGCACCTCCC GGGACTGTCA CTGAGCCGCT TCCCAGTGTG 60
ATTGTGCTGA GCGCAGGCCG GAAGATGGCG GCTGCGGCTG CGGCGGCCTC TGGCCCGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001370--BIR_rpt
IPR022103--BIRC6
IPR008979--Galactose-bd-like
IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50143--BIR_REPEAT_2
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00653--BIR
PF12356--BIRC6
PF00179--UQ_con

SMART

SM00238--BIR

Gene Ontology

GO:0005768--C:endosome
GO:0016020--C:membrane
GO:0005815--C:microtubule organizing center
GO:0030496--C:midbody
GO:0000922--C:spindle pole
GO:0005802--C:trans-Golgi network
GO:0004869--F:cysteine-type endopeptidase inhibitor activity
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0006915--P:apoptotic process
GO:0060711--P:labyrinthine layer development
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0008284--P:positive regulation of cell proliferation
GO:0032465--P:regulation of cytokinesis
GO:0060712--P:spongiotrophoblast layer development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000597	Aegilops tauschii	44.38	5.00e-34	140.00
IUUC-Aml-001583	Ailuropoda melanoleuca	97.48	0.00e+00	8707.00
IUUC-Atr-003108	Amborella trichopoda	42.86	4.00e-45	175.00
IUUC-Apl-004144	Anas platyrhynchos	92.10	0.00e+00	5613.00
IUUC-Aca-005257	Anolis carolinensis	89.71	0.00e+00	8006.00
IUUC-Aly-005551	Arabidopsis lyrata	37.83	7.00e-44	172.00
IUUC-Ath-007217	Arabidopsis thaliana	45.76	7.00e-44	171.00
IUUC-Acl-008031	Aspergillus clavatus	49.57	1.00e-31	132.00
IUUC-Afl-008480	Aspergillus flavus	36.36	6.00e-29	123.00
IUUC-Afu-009040	Aspergillus fumigatus	48.72	2.00e-30	127.00
IUUC-Ang-009816	Aspergillus niger	47.01	1.00e-27	119.00
IUUC-Aor-010121	Aspergillus oryzae	42.34	1.00e-24	108.00
IUUC-Ate-010487	Aspergillus terreus	48.72	2.00e-30	128.00
IUUC-Ame-011337	Astyanax mexicanus	77.91	0.00e+00	6640.00
IUUC-Bta-012501	Bos taurus	98.17	0.00e+00	8661.00
IUUC-Bdi-014931	Brachypodium distachyon	37.05	2.00e-46	180.00
IUUC-Bol-015976	Brassica oleracea	46.33	1.00e-45	177.00
IUUC-Bra-017967	Brassica rapa	46.33	5.00e-46	178.00
IUUC-Cel-018661	Caenorhabditis elegans	36.51	6.00e-79	288.00
IUUC-Cja-018746	Callithrix jacchus	96.76	0.00e+00	8554.00
IUUC-Cfa-020170	Canis familiaris	97.51	0.00e+00	8546.00
IUUC-Cpo-022138	Cavia porcellus	96.29	0.00e+00	5761.00
IUUC-Cre-022768	Chlamydomonas reinhardtii	44.69	1.00e-44	172.00
IUUC-Csa-023927	Chlorocebus sabaeus	96.92	0.00e+00	8584.00
IUUC-Cho-024890	Choloepus hoffmanni	93.52	0.00e+00	1923.00
IUUC-Cne-026995	Cryptococcus neoformans	30.74	4.00e-38	153.00
IUUC-Dre-027941	Danio rerio	79.59	0.00e+00	6999.00
IUUC-Dno-028913	Dasypus novemcinctus	95.12	0.00e+00	8441.00
IUUC-Dor-030715	Dipodomys ordii	93.76	0.00e+00	1935.00
IUUC-Dse-031232	Dothistroma septosporum	44.51	4.00e-38	153.00
IUUC-Dme-031592	Drosophila melanogaster	52.91	0.00e+00	673.00
IUUC-Ete-032587	Echinops telfairi	76.83	0.00e+00	2038.00
IUUC-Eca-033819	Equus caballus	97.60	0.00e+00	8607.00
IUUC-Eeu-034863	Erinaceus europaeus	86.97	0.00e+00	2533.00
IUUC-Fca-035505	Felis catus	94.42	0.00e+00	8322.00
IUUC-Fal-037318	Ficedula albicollis	91.90	0.00e+00	8198.00
IUUC-Gmo-039521	Gadus morhua	80.69	0.00e+00	1675.00
IUUC-Ggr-040040	Gaeumannomyces graminis	47.06	2.00e-33	138.00
IUUC-Gga-040728	Gallus gallus	91.91	0.00e+00	8114.00
IUUC-Gac-042251	Gasterosteus aculeatus	84.00	0.00e+00	1795.00
IUUC-Ggo-045562	Gorilla gorilla	95.70	0.00e+00	1597.00
IUUC-Hsa-046339	Homo sapiens	96.91	0.00e+00	8510.00
IUUC-Hvu-047441	Hordeum vulgare	46.70	4.00e-47	182.00
IUUC-Itr-048099	Ictidomys tridecemlineatus	96.71	0.00e+00	2682.00
IUUC-Lch-050164	Latimeria chalumnae	85.29	0.00e+00	7467.00
IUUC-Lpe-051294	Leersia perrieri	40.23	3.00e-47	182.00
IUUC-Loc-052800	Lepisosteus oculatus	84.85	0.00e+00	7461.00
IUUC-Laf-054034	Loxodonta africana	95.56	0.00e+00	8516.00
IUUC-Mcc-055267	Macaca mulatta	97.16	0.00e+00	8599.00
IUUC-Meu-056461	Macropus eugenii	92.12	0.00e+00	1220.00
IUUC-Mpo-057396	Magnaporthe poae	49.03	2.00e-34	141.00
IUUC-Mtr-057797	Medicago truncatula	39.52	4.00e-47	182.00
IUUC-Mla-059114	Melampsora laricipopulina	28.86	3.00e-41	163.00
IUUC-Mga-059594	Meleagris gallopavo	91.53	0.00e+00	7688.00
IUUC-Mmr-061179	Microcebus murinus	97.24	0.00e+00	8594.00
IUUC-Mdo-062990	Monodelphis domestica	93.20	0.00e+00	8154.00
IUUC-Mmu-063825	Mus musculus	94.39	0.00e+00	8392.00
IUUC-Mac-064881	Musa acuminata	43.41	6.00e-42	164.00
IUUC-Mpu-065908	Mustela putorius furo	97.52	0.00e+00	5566.00
IUUC-Mlu-067106	Myotis lucifugus	96.22	0.00e+00	8545.00
IUUC-Nfi-068366	Neosartorya fischeri	48.72	3.00e-30	127.00
IUUC-Nle-069347	Nomascus leucogenys	97.08	0.00e+00	8564.00
IUUC-Opr-070799	Ochotona princeps	87.21	0.00e+00	2563.00
IUUC-Ont-072046	Oreochromis niloticus	78.82	0.00e+00	6742.00
IUUC-Oan-073415	Ornithorhynchus anatinus	92.58	0.00e+00	3362.00
IUUC-Ocu-074556	Oryctolagus cuniculus	96.54	0.00e+00	8541.00
IUUC-Oba-075602	Oryza barthii	39.26	3.00e-40	159.00
IUUC-Obr-076463	Oryza brachyantha	35.82	4.00e-47	181.00
IUUC-Ogl-077040	Oryza glaberrima	39.26	3.00e-40	159.00
IUUC-Ogu-078917	Oryza glumaepatula	39.26	3.00e-40	159.00
IUUC-Oin-079561	Oryza indica	39.26	2.00e-40	159.00
IUUC-Olo-080416	Oryza longistaminata	39.63	6.00e-41	163.00
IUUC-Ome-081384	Oryza meridionalis	39.26	4.00e-40	159.00
IUUC-Oni-082241	Oryza nivara	39.26	3.00e-40	159.00
IUUC-Opu-083659	Oryza punctata	38.04	1.00e-46	181.00
IUUC-Oru-084622	Oryza rufipogon	39.26	3.00e-40	159.00
IUUC-Osa-085920	Oryza sativa	39.26	3.00e-40	159.00
IUUC-Ola-087459	Oryzias latipes	81.95	0.00e+00	2873.00
IUUC-Oga-088251	Otolemur garnettii	94.36	0.00e+00	8135.00
IUUC-Ptr-091512	Pan troglodytes	96.93	0.00e+00	8558.00
IUUC-Pan-092222	Papio anubis	96.10	0.00e+00	8539.00
IUUC-Pma-094574	Petromyzon marinus	61.14	0.00e+00	2966.00
IUUC-Pno-095065	Phaeosphaeria nodorum	46.83	7.00e-29	122.00
IUUC-Ppa-095592	Physcomitrella patens	29.45	2.00e-55	210.00
IUUC-Pfo-097086	Poecilia formosa	77.60	0.00e+00	6787.00
IUUC-Pab-098390	Pongo abelii	95.23	0.00e+00	8321.00
IUUC-Pop-099284	Populus trichocarpa	37.75	3.00e-42	166.00
IUUC-Pca-101036	Procavia capensis	88.15	0.00e+00	4100.00
IUUC-Ppe-101722	Prunus persica	36.67	3.00e-43	169.00
IUUC-Pva-103053	Pteropus vampyrus	92.04	0.00e+00	3536.00
IUUC-Pte-104333	Pyrenophora teres	41.29	9.00e-44	172.00
IUUC-Pyt-104498	Pyrenophora triticirepentis	39.39	4.00e-44	173.00
IUUC-Rno-106049	Rattus norvegicus	94.17	0.00e+00	6819.00
IUUC-Sha-107483	Sarcophilus harrisii	90.27	0.00e+00	7707.00
IUUC-Smo-108915	Selaginella moellendorffii	42.96	2.00e-44	172.00
IUUC-Sit-110087	Setaria italica	46.63	4.00e-44	172.00
IUUC-Sly-110929	Solanum lycopersicum	38.55	2.00e-46	180.00
IUUC-Stu-112554	Solanum tuberosum	38.96	1.00e-46	181.00
IUUC-Sar-112965	Sorex araneus	85.94	0.00e+00	1790.00
IUUC-Sbi-113880	Sorghum bicolor	34.82	2.00e-45	176.00
IUUC-Ssc-115927	Sus scrofa	98.11	0.00e+00	6038.00
IUUC-Tgu-117132	Taeniopygia guttata	91.60	0.00e+00	8085.00
IUUC-Tru-118115	Takifugu rubripes	75.78	0.00e+00	6589.00
IUUC-Tsy-118899	Tarsius syrichta	93.72	0.00e+00	5018.00
IUUC-Tni-120891	Tetraodon nigroviridis	74.57	0.00e+00	6562.00
IUUC-Tca-121636	Theobroma cacao	37.75	1.00e-42	167.00
IUUC-Tae-125407	Triticum aestivum	47.25	2.00e-47	183.00
IUUC-Tur-126479	Triticum urartu	46.41	2.00e-43	170.00
IUUC-Tme-126930	Tuber melanosporum	42.60	6.00e-48	186.00
IUUC-Tbe-127630	Tupaia belangeri	92.84	0.00e+00	1515.00
IUUC-Ttr-128629	Tursiops truncatus	95.50	0.00e+00	8412.00
IUUC-Vpa-130310	Vicugna pacos	96.48	0.00e+00	8292.00
IUUC-Vvi-131664	Vitis vinifera	40.09	4.00e-36	145.00
IUUC-Xtr-131861	Xenopus tropicalis	83.59	0.00e+00	7235.00
IUUC-Xma-133613	Xiphophorus maculatus	77.62	0.00e+00	6744.00
IUUC-Zma-135768	Zea mays	35.67	1.00e-45	179.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence