iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013440

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Hypothetical LOC540154

Genbank Nucleotide ID

DAAA02002417

Gene Name

TRIM59; MGC137058

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000008078.3	ENSBTAT00000010623.3	ENSBTAP00000010623.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	5.20e-06	26.6	6	89
E3 activity/RING/RING	2.30e-09	37.8	10	60

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk...........tcPvtrqpl.....teedlvPnltlrrliqawcee 71
           +e+ CpI + +++dP vlp+ +t+ r+++e  l+  g+           +cP +r+ +       e+l  n +lr++i+++ +e
   Q: 6    DELTCPICYSIFEDPRVLPCSHTFCRNCLENVLQATGNfyiwrplriplKCPNCRSIIeiapsGIESLPVNFALRAIIEKYQQE 89
           7899*****************************999999999*****9999999987744322346677788999999998776 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefr..........CPlCr 46
           C+iC++ f+d p+vlpC H+f+++Cl+++     ++ ++f+          CP Cr
   Q: 10   CPICYSIFED-PRVLPCSHTFCRNCLENV----LQATGNFYiwrplriplkCPNCR 60
           **********.***************999....444444444555555555****8 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MHNFEDELTC PICYSIFEDP RVLPCSHTFC RNCLENVLQA TGNFYIWRPL RIPLKCPNCR 60
SIIEIAPSGI ESLPVNFALR AIIEKYQQED HPDIITCPEH YRQPLNVYCL LDKKLVCGHC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAGCTATTG ATATTTGTCA CTACTTTAAA ACACACACAC ACACAATGAG GCTCAGGGAA 60
GGTAAGTATC AAAGATAGTT ATATTTCCTA TCATGTACTT AACGTTTTTT TGAGAATTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0005813--C:centrosome
GO:0005929--C:cilium
GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:0030992--C:intraciliary transport particle B
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0060271--P:cilium assembly
GO:0045087--P:innate immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046597--P:negative regulation of viral entry into host cell

KEGG

bta:540154

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002249	Ailuropoda melanoleuca	91.44	0.00e+00	683.00
IUUC-Apl-003996	Anas platyrhynchos	68.35	1.00e-122	432.00
IUUC-Aca-005141	Anolis carolinensis	59.89	3.00e-128	451.00
IUUC-Ame-011353	Astyanax mexicanus	51.45	2.00e-98	352.00
IUUC-Cfa-021168	Canis familiaris	92.82	0.00e+00	693.00
IUUC-Cpo-021702	Cavia porcellus	78.12	2.00e-164	572.00
IUUC-Csa-024141	Chlorocebus sabaeus	91.16	6.00e-178	616.00
IUUC-Dre-028408	Danio rerio	47.44	9.00e-89	320.00
IUUC-Dno-029180	Dasypus novemcinctus	91.71	0.00e+00	678.00
IUUC-Ete-033028	Echinops telfairi	86.79	1.00e-166	580.00
IUUC-Eca-034357	Equus caballus	92.82	0.00e+00	657.00
IUUC-Fca-036287	Felis catus	93.92	0.00e+00	695.00
IUUC-Gga-040739	Gallus gallus	62.43	1.00e-131	462.00
IUUC-Ggo-045307	Gorilla gorilla	88.95	0.00e+00	642.00
IUUC-Hsa-045690	Homo sapiens	89.50	0.00e+00	642.00
IUUC-Itr-048230	Ictidomys tridecemlineatus	93.37	0.00e+00	698.00
IUUC-Laf-054522	Loxodonta africana	89.20	0.00e+00	672.00
IUUC-Mcc-055145	Macaca mulatta	91.71	0.00e+00	655.00
IUUC-Meu-056214	Macropus eugenii	47.62	2.00e-61	229.00
IUUC-Mmr-061197	Microcebus murinus	94.48	0.00e+00	703.00
IUUC-Mdo-062631	Monodelphis domestica	62.81	1.00e-125	442.00
IUUC-Mmu-064217	Mus musculus	86.74	2.00e-179	621.00
IUUC-Mpu-065691	Mustela putorius furo	94.20	0.00e+00	700.00
IUUC-Mlu-067742	Myotis lucifugus	90.58	0.00e+00	654.00
IUUC-Nle-069722	Nomascus leucogenys	90.33	0.00e+00	680.00
IUUC-Oan-073382	Ornithorhynchus anatinus	64.12	6.00e-128	450.00
IUUC-Oar-089206	Ovis aries	98.06	0.00e+00	725.00
IUUC-Pan-092189	Papio anubis	91.99	0.00e+00	658.00
IUUC-Psi-093523	Pelodiscus sinensis	74.07	1.00e-134	472.00
IUUC-Pma-094162	Petromyzon marinus	33.23	5.00e-47	181.00
IUUC-Pfo-096032	Poecilia formosa	46.62	4.00e-88	318.00
IUUC-Pva-103089	Pteropus vampyrus	93.07	0.00e+00	669.00
IUUC-Pgr-103338	Puccinia graminis	37.10	3.00e-06	45.40
IUUC-Rno-105440	Rattus norvegicus	88.12	0.00e+00	632.00
IUUC-Ssc-115809	Sus scrofa	90.86	0.00e+00	647.00
IUUC-Tru-118402	Takifugu rubripes	44.63	4.00e-94	337.00
IUUC-Tni-119737	Tetraodon nigroviridis	44.69	2.00e-84	305.00
IUUC-Ttr-128921	Tursiops truncatus	93.92	0.00e+00	670.00
IUUC-Vpa-130397	Vicugna pacos	93.37	0.00e+00	693.00
IUUC-Xtr-132752	Xenopus tropicalis	44.32	5.00e-84	304.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence