iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069722

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01169697

Gene Name

TRIM59

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000004563.1	ENSNLET00000005821.1	ENSNLEP00000005535.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.90e-09	37.9	10	60
E3 activity/RING/U-box	2.40e-06	27.5	6	89

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefr..........CPlCr 46
           C+iC++ f+d p+vlpC H+f+++Cl+++     ++s++f+          CP Cr
   Q: 10   CPICYSIFED-PRVLPCSHTFCRNCLENI----LQASGNFYiwrplriplkCPNCR 60
           **********.***************999....567777766666666777****8 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk...........tcPvtrqpl.....teedlvPnltlrrliqawcee 71
           ee+ CpI + +++dP vlp+ +t+ r+++e  l+ +g+           +cP +r+ +       e+l  n +lr++i+++ +e
   Q: 6    EELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNfyiwrplriplKCPNCRSIIeiaptGIESLPVNFALRAIIEKYQQE 89
           7999*****************************999999**********99999986533321456777799999999999776 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MHNFEEELTC PICYSIFEDP RVLPCSHTFC RNCLENILQA SGNFYIWRPL RIPLKCPNCR 60
SIIEIAPTGI ESLPVNFALR AIIEKYQQED HPDIVTCPEH YRQPLNVYCL LDKKLVCGHC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCGGGGCG GAGGAGGGCG GGGACTCGGG GCGGCTCTCA GCATCCGCCT GGAGCCCGTG 60
GCGCTGTGTT TCGGCGCTGT GGAGTTGCCT GGTCCGCCTC CTCCCCGCGG TGAGTCTAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005622--C:intracellular
GO:0008270--F:zinc ion binding
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling

KEGG

nle:100606259

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002249	Ailuropoda melanoleuca	89.05	0.00e+00	745.00
IUUC-Apl-003996	Anas platyrhynchos	58.77	4.00e-124	437.00
IUUC-Aca-005141	Anolis carolinensis	57.53	2.00e-133	469.00
IUUC-Ame-011353	Astyanax mexicanus	52.12	2.00e-99	355.00
IUUC-Bta-013440	Bos taurus	90.33	0.00e+00	680.00
IUUC-Cfa-021168	Canis familiaris	89.03	0.00e+00	741.00
IUUC-Cpo-021702	Cavia porcellus	74.88	2.00e-174	605.00
IUUC-Csa-024141	Chlorocebus sabaeus	95.04	0.00e+00	724.00
IUUC-Dre-028408	Danio rerio	46.91	6.00e-88	317.00
IUUC-Dno-029180	Dasypus novemcinctus	87.84	0.00e+00	722.00
IUUC-Ete-033028	Echinops telfairi	86.16	5.00e-166	578.00
IUUC-Eca-034357	Equus caballus	88.34	0.00e+00	712.00
IUUC-Fca-036287	Felis catus	89.83	0.00e+00	747.00
IUUC-Gga-040739	Gallus gallus	58.13	3.00e-136	478.00
IUUC-Ggo-045307	Gorilla gorilla	95.29	0.00e+00	763.00
IUUC-Hsa-045690	Homo sapiens	95.53	0.00e+00	763.00
IUUC-Itr-048230	Ictidomys tridecemlineatus	90.32	0.00e+00	752.00
IUUC-Laf-054522	Loxodonta africana	85.07	0.00e+00	710.00
IUUC-Mcc-055145	Macaca mulatta	95.04	0.00e+00	761.00
IUUC-Meu-056214	Macropus eugenii	47.48	6.00e-61	227.00
IUUC-Mmr-061197	Microcebus murinus	91.32	0.00e+00	761.00
IUUC-Mdo-062631	Monodelphis domestica	60.00	6.00e-135	473.00
IUUC-Mmu-064217	Mus musculus	83.83	0.00e+00	672.00
IUUC-Mpu-065691	Mustela putorius furo	91.07	0.00e+00	760.00
IUUC-Mlu-067742	Myotis lucifugus	87.28	0.00e+00	695.00
IUUC-Oan-073382	Ornithorhynchus anatinus	61.29	4.00e-139	487.00
IUUC-Oar-089206	Ovis aries	88.59	0.00e+00	744.00
IUUC-Pan-092189	Papio anubis	95.29	0.00e+00	763.00
IUUC-Psi-093523	Pelodiscus sinensis	62.56	4.00e-144	504.00
IUUC-Pma-094162	Petromyzon marinus	32.51	6.00e-48	184.00
IUUC-Pfo-096032	Poecilia formosa	46.91	5.00e-88	318.00
IUUC-Pva-103089	Pteropus vampyrus	87.78	0.00e+00	702.00
IUUC-Pgr-103338	Puccinia graminis	36.23	1.00e-06	47.00
IUUC-Rno-105440	Rattus norvegicus	85.07	0.00e+00	683.00
IUUC-Ssc-115809	Sus scrofa	86.60	0.00e+00	700.00
IUUC-Tru-118402	Takifugu rubripes	43.79	3.00e-95	341.00
IUUC-Tni-119737	Tetraodon nigroviridis	44.81	3.00e-85	307.00
IUUC-Ttr-128921	Tursiops truncatus	88.28	0.00e+00	709.00
IUUC-Vpa-130397	Vicugna pacos	88.56	0.00e+00	740.00
IUUC-Xtr-132752	Xenopus tropicalis	43.48	5.00e-83	301.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence