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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063358
UUCD1 version UUC-MuM-00044
Ensembl Protein ID ENSMUSP00000030471.8
UniProt Accession Q8K1C9; A2A911; Q3U3S2; Q6IQY7; Q91VX4; LRC41_MOUSE
Genbank Protein ID BAE32713.1; CAM22675.1; AAH07169.1; AAH22976.2; AAH71258.1
Protein Name Leucine-rich repeat-containing protein 41; Protein Muf1
Genbank Nucleotide ID AK154613; AL627105; BC007169; BC022976; BC071258
Gene Name Lrrc41; Muf1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000028703.14 ENSMUST00000030471.8 ENSMUSP00000030471.8
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRepTarmiRNAMap
RAID2
Protein-protein Interaction
IIDHINTMentha
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTMUniProt
PHOSIDA
Protein Expression/Proteomics
GPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box SOCS 11384984
Reviewed
Classification
Family Identity E-value Score Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box 93.72 0.00e+00 1306.00 IUUC-Hsa-045863
Organism Mus musculus
Functional Description
(View)

Functional Description


     Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
 Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Protein Sequence
(Fasta)
MAAPEAWRAR SCWFCEVAAA TTMEATSREA APAKSSASGP SAPPALFELC GRAVSAHMGV 60
LESGVWALPG PILQSILPLL NIYYLERIEE TALKKGLSTQ AIWRRLWDEL MKTRPSSLES 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063358|E3,SOCS|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGTCATCTGC TCCTCTGTTT GACGATCTTT TAATGTTGTT TCTGTTCTTC CCCATATCCC 60
TTATGGAGCG GTCCTAAAAG CTGACCTCTT CAAGATGGCG GCCCGCGGGT GTCATTCTCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063358|E3,SOCS|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0433--Leucine-rich repeat
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
Interpro

IPR032675--L_dom-like
IPR026137--Leu_rpt_41
Gene Ontology

GO:0005737--C:cytoplasm
GO:0016020--C:membrane
GO:0005634--C:nucleus
GO:0042803--F:protein homodimerization activity
GO:0016567--P:protein ubiquitination
KEGG mmu:230654
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Apl-003769 Anas platyrhynchos 53.23 2.00e-164 573.00
IUUC-Aca-005345 Anolis carolinensis 48.08 1.00e-159 556.00
IUUC-Ame-011074 Astyanax mexicanus 32.69 5.00e-17 82.40
IUUC-Bta-012962 Bos taurus 89.83 0.00e+00 655.00
IUUC-Cja-019020 Callithrix jacchus 93.09 0.00e+00 1305.00
IUUC-Cfa-020137 Canis familiaris 93.61 0.00e+00 1296.00
IUUC-Cpo-021856 Cavia porcellus 93.73 0.00e+00 1296.00
IUUC-Csa-024137 Chlorocebus sabaeus 94.18 0.00e+00 1249.00
IUUC-Dre-027630 Danio rerio 28.94 7.00e-23 102.00
IUUC-Dno-028994 Dasypus novemcinctus 93.94 0.00e+00 1302.00
IUUC-Dse-031281 Dothistroma septosporum 27.84 2.30e-01 30.40
IUUC-Ete-032443 Echinops telfairi 84.99 7.00e-149 521.00
IUUC-Eca-033730 Equus caballus 88.33 0.00e+00 1192.00
IUUC-Eeu-034789 Erinaceus europaeus 91.40 0.00e+00 1160.00
IUUC-Fca-035714 Felis catus 92.38 0.00e+00 1230.00
IUUC-Fal-036765 Ficedula albicollis 52.89 2.00e-179 622.00
IUUC-Fso-038317 Fusarium solani 34.09 3.40e-01 29.30
IUUC-Gmo-038656 Gadus morhua 22.35 2.00e-04 38.90
IUUC-Gga-040164 Gallus gallus 50.61 1.00e-178 619.00
IUUC-Gac-041941 Gasterosteus aculeatus 34.51 4.00e-25 108.00
IUUC-Ggo-045159 Gorilla gorilla 93.84 0.00e+00 1297.00
IUUC-Hsa-045863 Homo sapiens 93.84 0.00e+00 1297.00
IUUC-Itr-048804 Ictidomys tridecemlineatus 94.09 0.00e+00 1239.00
IUUC-Lpe-051218 Leersia perrieri 31.25 5.00e-03 33.50
IUUC-Loc-052391 Lepisosteus oculatus 40.17 2.00e-35 144.00
IUUC-Lma-053146 Leptosphaeria maculans 32.39 2.20e-02 34.70
IUUC-Laf-054362 Loxodonta africana 93.12 0.00e+00 1280.00
IUUC-Mcc-055382 Macaca mulatta 94.17 0.00e+00 1183.00
IUUC-Meu-056890 Macropus eugenii 51.93 0.00e+00 682.00
IUUC-Mla-058850 Melampsora laricipopulina 25.93 8.20e-02 31.60
IUUC-Mga-059832 Meleagris gallopavo 52.11 2.00e-162 566.00
IUUC-Mmr-061383 Microcebus murinus 93.73 0.00e+00 1358.00
IUUC-Mdo-062507 Monodelphis domestica 59.70 0.00e+00 821.00
IUUC-Mpu-066845 Mustela putorius furo 93.87 0.00e+00 1298.00
IUUC-Mlu-067006 Myotis lucifugus 90.95 0.00e+00 1270.00
IUUC-Nle-069386 Nomascus leucogenys 93.60 0.00e+00 1293.00
IUUC-Opr-070396 Ochotona princeps 95.62 1.00e-116 414.00
IUUC-Oan-073068 Ornithorhynchus anatinus 56.59 1.00e-117 417.00
IUUC-Ocu-074054 Oryctolagus cuniculus 93.73 0.00e+00 1277.00
IUUC-Ogl-077410 Oryza glaberrima 27.66 1.10e-02 35.00
IUUC-Oin-079496 Oryza indica 27.66 1.00e-02 35.00
IUUC-Olo-080740 Oryza longistaminata 27.66 1.10e-02 34.70
IUUC-Oni-082831 Oryza nivara 27.66 1.20e-02 34.70
IUUC-Oru-084740 Oryza rufipogon 27.66 1.10e-02 35.40
IUUC-Osa-085903 Oryza sativa 27.66 1.10e-02 35.00
IUUC-Oga-088549 Otolemur garnettii 93.24 0.00e+00 1310.00
IUUC-Oar-089776 Ovis aries 92.52 0.00e+00 1196.00
IUUC-Ptr-090774 Pan troglodytes 93.84 0.00e+00 1297.00
IUUC-Pan-092510 Papio anubis 94.46 0.00e+00 1296.00
IUUC-Psi-094058 Pelodiscus sinensis 54.57 0.00e+00 630.00
IUUC-Pma-094518 Petromyzon marinus 31.00 6.00e-15 75.10
IUUC-Ppa-095577 Physcomitrella patens 28.00 1.60e-02 33.10
IUUC-Pfo-097181 Poecilia formosa 35.01 1.00e-25 111.00
IUUC-Pab-098616 Pongo abelii 81.03 0.00e+00 1013.00
IUUC-Pop-100048 Populus trichocarpa 30.00 2.00e-03 35.00
IUUC-Pca-101105 Procavia capensis 90.98 0.00e+00 964.00
IUUC-Pva-102749 Pteropus vampyrus 88.38 4.00e-159 555.00
IUUC-Rno-105070 Rattus norvegicus 96.66 0.00e+00 1381.00
IUUC-Sce-106163 Saccharomyces cerevisiae 30.99 1.80e+00 29.30
IUUC-Sha-106634 Sarcophilus harrisii 53.65 7.00e-142 497.00
IUUC-Sar-113288 Sorex araneus 90.99 0.00e+00 681.00
IUUC-Ssc-115559 Sus scrofa 92.50 0.00e+00 1236.00
IUUC-Tgu-116561 Taeniopygia guttata 50.78 2.00e-177 615.00
IUUC-Tni-120099 Tetraodon nigroviridis 31.43 4.00e-17 82.80
IUUC-Tme-127168 Tuber melanosporum 22.63 2.80e-02 33.10
IUUC-Tbe-127527 Tupaia belangeri 87.95 7.00e-133 468.00
IUUC-Ttr-128532 Tursiops truncatus 92.68 0.00e+00 1192.00
IUUC-Xtr-131881 Xenopus tropicalis 56.61 1.00e-67 250.00
Created Date 25-Jun-2017

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