iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-116559

Ensembl Protein ID

ENSTGUP00000010036.1

UniProt Accession

H0ZHH1; H0ZHH1_TAEGU

Genbank Protein ID

ENSTGUP00000010036

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01012859

Gene Name

NCK2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000009731.1	ENSTGUT00000010143.1	ENSTGUP00000010036.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.00e-39	131.3	196	248

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPe 56
           +++ vq+ly++++++d+eL+++kG +++viek e+d +W+k+ k+ +g+ Gl+P+
   Q: 196  VLHIVQTLYPFSSVTDEELNFEKG-TMEVIEKPENDPEWWKC-KNSRGQIGLVPK 248
           5789********************.79***************.7**********7 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MTEEVIVIAK WDYTAQQDQE LDIKKNERLW LLDDSKTWWR VRNAANKTGY VPSNYVERKN 60
SLKKGSLVKN LKDTLGLGKT KRKTSARDAS PTPSTDAEYP SNGSSADRIY DLNIPAYVKF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACAGAAG AAGTTATTGT TATTGCAAAG TGGGATTACA CTGCACAGCA GGACCAAGAA 60
CTTGACATCA AGAAAAATGA GCGTCTTTGG CTATTAGATG ATTCTAAGAC ATGGTGGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR017304--NCK
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0012506--C:vesicle membrane
GO:0007015--P:actin filament organization
GO:0016477--P:cell migration
GO:0048013--P:ephrin receptor signaling pathway
GO:0030032--P:lamellipodium assembly
GO:1903912--P:negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
GO:0033137--P:negative regulation of peptidyl-serine phosphorylation
GO:1903898--P:negative regulation of PERK-mediated unfolded protein response
GO:1990441--P:negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
GO:0030838--P:positive regulation of actin filament polymerization
GO:1902237--P:positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:0042102--P:positive regulation of T cell proliferation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0036493--P:positive regulation of translation in response to endoplasmic reticulum stress

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001404	Ailuropoda melanoleuca	90.26	0.00e+00	699.00
IUUC-Apl-003456	Anas platyrhynchos	96.84	0.00e+00	734.00
IUUC-Aca-005105	Anolis carolinensis	95.26	0.00e+00	724.00
IUUC-Ame-010966	Astyanax mexicanus	77.60	1.00e-170	592.00
IUUC-Bta-012424	Bos taurus	83.51	5.00e-178	616.00
IUUC-Cel-018144	Caenorhabditis elegans	41.42	5.00e-71	261.00
IUUC-Cja-019898	Callithrix jacchus	91.05	0.00e+00	705.00
IUUC-Cfa-020830	Canis familiaris	89.21	0.00e+00	693.00
IUUC-Cpo-021487	Cavia porcellus	82.37	1.00e-177	614.00
IUUC-Csa-023693	Chlorocebus sabaeus	91.05	0.00e+00	706.00
IUUC-Cho-024368	Choloepus hoffmanni	65.52	1.00e-127	448.00
IUUC-Cin-025348	Ciona intestinalis	37.94	4.00e-65	241.00
IUUC-Csv-026046	Ciona savignyi	39.05	1.00e-65	243.00
IUUC-Dre-028334	Danio rerio	80.16	4.00e-174	603.00
IUUC-Dno-028973	Dasypus novemcinctus	91.32	0.00e+00	702.00
IUUC-Dor-031003	Dipodomys ordii	88.42	0.00e+00	658.00
IUUC-Dme-031846	Drosophila melanogaster	40.54	7.00e-85	307.00
IUUC-Ete-032792	Echinops telfairi	83.07	0.00e+00	632.00
IUUC-Eca-033656	Equus caballus	90.53	0.00e+00	701.00
IUUC-Eeu-034743	Erinaceus europaeus	63.25	6.00e-135	473.00
IUUC-Fca-036347	Felis catus	90.53	0.00e+00	700.00
IUUC-Fal-037095	Ficedula albicollis	97.37	0.00e+00	737.00
IUUC-Gmo-039410	Gadus morhua	68.37	2.00e-154	538.00
IUUC-Gga-040155	Gallus gallus	96.84	0.00e+00	734.00
IUUC-Gac-041787	Gasterosteus aculeatus	70.81	6.00e-160	556.00
IUUC-Ggo-044805	Gorilla gorilla	90.79	0.00e+00	703.00
IUUC-Hsa-046585	Homo sapiens	90.79	0.00e+00	703.00
IUUC-Itr-048887	Ictidomys tridecemlineatus	89.21	0.00e+00	675.00
IUUC-Lch-049795	Latimeria chalumnae	90.00	0.00e+00	690.00
IUUC-Loc-051985	Lepisosteus oculatus	88.68	0.00e+00	658.00
IUUC-Laf-054228	Loxodonta africana	93.16	0.00e+00	710.00
IUUC-Mcc-055402	Macaca mulatta	91.05	0.00e+00	706.00
IUUC-Meu-056139	Macropus eugenii	64.83	7.00e-140	489.00
IUUC-Mga-059374	Meleagris gallopavo	96.84	0.00e+00	734.00
IUUC-Mmr-061453	Microcebus murinus	90.53	0.00e+00	701.00
IUUC-Mdo-063080	Monodelphis domestica	95.00	0.00e+00	723.00
IUUC-Mmu-063529	Mus musculus	87.37	0.00e+00	671.00
IUUC-Mpu-066815	Mustela putorius furo	90.26	0.00e+00	699.00
IUUC-Mlu-067132	Myotis lucifugus	86.23	1.00e-150	525.00
IUUC-Nle-069371	Nomascus leucogenys	90.79	0.00e+00	703.00
IUUC-Opr-070948	Ochotona princeps	89.66	0.00e+00	659.00
IUUC-Ont-071410	Oreochromis niloticus	74.81	1.00e-159	555.00
IUUC-Oan-073304	Ornithorhynchus anatinus	92.81	4.00e-161	560.00
IUUC-Ocu-074783	Oryctolagus cuniculus	89.74	0.00e+00	678.00
IUUC-Ola-086808	Oryzias latipes	71.79	4.00e-154	536.00
IUUC-Oga-088391	Otolemur garnettii	90.79	0.00e+00	687.00
IUUC-Oar-090025	Ovis aries	78.19	3.00e-160	557.00
IUUC-Ptr-090975	Pan troglodytes	90.79	0.00e+00	703.00
IUUC-Pan-092287	Papio anubis	91.05	0.00e+00	706.00
IUUC-Psi-093413	Pelodiscus sinensis	95.79	0.00e+00	728.00
IUUC-Pfo-097129	Poecilia formosa	74.94	4.00e-165	573.00
IUUC-Pab-098756	Pongo abelii	90.79	0.00e+00	703.00
IUUC-Pca-100235	Procavia capensis	80.00	1.00e-178	618.00
IUUC-Pva-102294	Pteropus vampyrus	86.84	0.00e+00	667.00
IUUC-Rno-105090	Rattus norvegicus	87.37	0.00e+00	670.00
IUUC-Sha-107521	Sarcophilus harrisii	95.00	0.00e+00	726.00
IUUC-Sar-113697	Sorex araneus	83.33	0.00e+00	625.00
IUUC-Ssc-115958	Sus scrofa	81.01	2.00e-154	538.00
IUUC-Tru-117677	Takifugu rubripes	74.18	1.00e-160	558.00
IUUC-Tsy-119184	Tarsius syrichta	62.91	2.00e-123	435.00
IUUC-Tni-120434	Tetraodon nigroviridis	74.16	1.00e-157	548.00
IUUC-Tbe-127931	Tupaia belangeri	88.29	5.00e-169	585.00
IUUC-Ttr-128993	Tursiops truncatus	83.51	1.00e-178	618.00
IUUC-Vpa-130344	Vicugna pacos	68.50	2.00e-151	528.00
IUUC-Xtr-132543	Xenopus tropicalis	86.35	0.00e+00	666.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence