iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050211

Ensembl Protein ID

ENSLACP00000017082.1

UniProt Accession

H3B5B1; H3B5B1_LATCH

Genbank Protein ID

ENSLACP00000017082

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01052896

Gene Name

KLHL25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000015053.1	ENSLACT00000017207.1	ENSLACP00000017082.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.40e-18	67.2	46	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.80e-07	30.4	146	177

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgkldene 69
           +Dv+l  g + f++h++vLaa+S++F+a+f+++l+e+   ++v+++d + pev++ ll+F Y++++ +ne
   Q: 46   TDVTLWSGSRSFPCHRAVLAACSRYFEAMFSNGLRETL-DSEVNFHDnIHPEVLELLLDFAYSSRIIINE 114
           7************************************9.*******99*****************99987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclg++ ++d+++c++L++   +++l hF+
   Q: 146  SSNCLGMMLLSDAHQCRRLYELSWRMCLVHFE 177
           69*****************************5 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MSVSVHEARK SRSSTGSMNI SLFHKPSHPD SVLTHLNSLR KQCMFTDVTL WSGSRSFPCH 60
RAVLAACSRY FEAMFSNGLR ETLDSEVNFH DNIHPEVLEL LLDFAYSSRI IINEENAESL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGGTGA GCGTCCATGA GGCCCGTAAG TCCCGCAGCA GTACGGGTTC CATGAACATC 60
TCTTTATTCC ATAAACCTTC TCACCCGGAT AGTGTTCTGA CCCACCTGAA CTCCCTAAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030565--KLHL25
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination
GO:0006446--P:regulation of translational initiation

KEGG

lcm:102348130

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002373	Ailuropoda melanoleuca	86.59	0.00e+00	1095.00
IUUC-Apl-003543	Anas platyrhynchos	87.97	0.00e+00	1071.00
IUUC-Aca-004729	Anolis carolinensis	85.71	0.00e+00	1059.00
IUUC-Ame-011020	Astyanax mexicanus	90.99	0.00e+00	1098.00
IUUC-Bta-012955	Bos taurus	85.20	0.00e+00	1079.00
IUUC-Cja-018839	Callithrix jacchus	86.22	0.00e+00	1086.00
IUUC-Cfa-020224	Canis familiaris	86.59	0.00e+00	1094.00
IUUC-Cpo-021593	Cavia porcellus	84.69	0.00e+00	1030.00
IUUC-Csa-023276	Chlorocebus sabaeus	86.56	0.00e+00	1091.00
IUUC-Dre-028053	Danio rerio	89.97	0.00e+00	1066.00
IUUC-Dno-029287	Dasypus novemcinctus	85.20	0.00e+00	1072.00
IUUC-Fca-035897	Felis catus	86.93	0.00e+00	1096.00
IUUC-Fal-037036	Ficedula albicollis	88.46	0.00e+00	1082.00
IUUC-Gmo-039345	Gadus morhua	88.10	0.00e+00	1042.00
IUUC-Gga-040404	Gallus gallus	88.12	0.00e+00	1081.00
IUUC-Gac-042447	Gasterosteus aculeatus	88.61	0.00e+00	1062.00
IUUC-Ggo-045060	Gorilla gorilla	86.56	0.00e+00	1091.00
IUUC-Hsa-046494	Homo sapiens	86.56	0.00e+00	1090.00
IUUC-Itr-047993	Ictidomys tridecemlineatus	86.90	0.00e+00	1092.00
IUUC-Loc-052578	Lepisosteus oculatus	90.31	0.00e+00	1098.00
IUUC-Laf-053498	Loxodonta africana	86.22	0.00e+00	1044.00
IUUC-Mcc-055033	Macaca mulatta	86.56	0.00e+00	1091.00
IUUC-Meu-056893	Macropus eugenii	87.93	0.00e+00	1103.00
IUUC-Mga-060025	Meleagris gallopavo	88.29	0.00e+00	1081.00
IUUC-Mmr-060658	Microcebus murinus	86.90	0.00e+00	1093.00
IUUC-Mdo-062667	Monodelphis domestica	88.10	0.00e+00	1102.00
IUUC-Mmu-063125	Mus musculus	85.54	0.00e+00	1040.00
IUUC-Mpu-066209	Mustela putorius furo	86.25	0.00e+00	1092.00
IUUC-Mlu-068237	Myotis lucifugus	84.35	0.00e+00	1040.00
IUUC-Nle-069454	Nomascus leucogenys	86.45	0.00e+00	1078.00
IUUC-Ont-072138	Oreochromis niloticus	88.95	0.00e+00	1052.00
IUUC-Oan-073320	Ornithorhynchus anatinus	81.80	0.00e+00	1031.00
IUUC-Ocu-073765	Oryctolagus cuniculus	82.31	0.00e+00	1016.00
IUUC-Oga-088002	Otolemur garnettii	86.22	0.00e+00	1081.00
IUUC-Oar-089481	Ovis aries	85.03	0.00e+00	1078.00
IUUC-Ptr-091200	Pan troglodytes	86.39	0.00e+00	1085.00
IUUC-Psi-093884	Pelodiscus sinensis	87.59	0.00e+00	1068.00
IUUC-Pma-094515	Petromyzon marinus	58.86	0.00e+00	673.00
IUUC-Pva-102321	Pteropus vampyrus	85.20	0.00e+00	1076.00
IUUC-Rno-104835	Rattus norvegicus	85.54	0.00e+00	1040.00
IUUC-Sha-107528	Sarcophilus harrisii	87.93	0.00e+00	1105.00
IUUC-Ssc-116161	Sus scrofa	86.56	0.00e+00	1091.00
IUUC-Tgu-116569	Taeniopygia guttata	88.29	0.00e+00	1078.00
IUUC-Tni-120525	Tetraodon nigroviridis	77.83	0.00e+00	915.00
IUUC-Ttr-129297	Tursiops truncatus	86.22	0.00e+00	1087.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence