iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	77.49	1.00e-89	327.00	IUUC-Hsa-046646
UBD/Alpha-Helix/UBA	91.43	3.00e-130	462.00	IUUC-Mmu-063304

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MHAWDPPASL SRALPLASSV LMLLLSCLWL LGAGPSLRLA PELLTEPWQV HRLLTHALGH 60
TALPGLLLSL LLLPTLGWWQ ECHLGTLRFL HNSAVLALAT GLLAVLLAGL GLSSAAGGCG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGTCCGTC TGCTTGGGAG GGAGGCCGGG AATGCCGCGC CCGACCCCAG TAACGGTCGG 60
AGTCCAGAAG CCCTATAATC ATCCATCCTT CAACTCATAC CCTTGTCTTA ACAGAAAACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR022764--Peptidase_S54_rhomboid_dom
IPR015940--UBA
IPR009060--UBA-like

Pfam

PF01694--Rhomboid
PF00627--UBA

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005622--C:intracellular
GO:0004252--F:serine-type endopeptidase activity
GO:0001889--P:liver development
GO:0000165--P:MAPK cascade
GO:0032815--P:negative regulation of natural killer cell activation
GO:0045732--P:positive regulation of protein catabolic process
GO:0002673--P:regulation of acute inflammatory response
GO:0050708--P:regulation of protein secretion
GO:0009410--P:response to xenobiotic stimulus

KEGG

rno:289753

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001619	Ailuropoda melanoleuca	77.22	8.00e-68	250.00
IUUC-Aca-004494	Anolis carolinensis	40.28	1.00e-17	84.30
IUUC-Ame-010805	Astyanax mexicanus	47.66	3.00e-17	82.80
IUUC-Bta-012844	Bos taurus	75.37	8.00e-56	210.00
IUUC-Cja-019853	Callithrix jacchus	77.05	1.00e-80	293.00
IUUC-Cfa-021026	Canis familiaris	77.22	3.00e-84	305.00
IUUC-Csa-023360	Chlorocebus sabaeus	77.62	1.00e-86	313.00
IUUC-Dre-027575	Danio rerio	54.88	5.00e-18	85.10
IUUC-Dno-029113	Dasypus novemcinctus	73.43	5.00e-62	231.00
IUUC-Dor-030646	Dipodomys ordii	77.91	2.00e-95	342.00
IUUC-Eca-034158	Equus caballus	76.42	4.00e-83	301.00
IUUC-Eeu-034983	Erinaceus europaeus	58.33	5.00e-48	183.00
IUUC-Fca-035531	Felis catus	78.89	1.00e-95	343.00
IUUC-Ggo-045015	Gorilla gorilla	77.62	7.00e-80	290.00
IUUC-Hsa-046646	Homo sapiens	77.62	2.00e-81	296.00
IUUC-Itr-048164	Ictidomys tridecemlineatus	77.28	2.00e-95	342.00
IUUC-Lch-049560	Latimeria chalumnae	34.20	2.00e-08	53.10
IUUC-Laf-054308	Loxodonta africana	74.22	4.00e-77	281.00
IUUC-Mcc-055034	Macaca mulatta	68.86	3.00e-66	244.00
IUUC-Meu-056317	Macropus eugenii	51.18	9.00e-35	140.00
IUUC-Mmr-061591	Microcebus murinus	75.23	3.00e-60	225.00
IUUC-Mdo-062745	Monodelphis domestica	53.06	1.00e-38	153.00
IUUC-Mmu-063304	Mus musculus	91.43	7.00e-133	466.00
IUUC-Mac-065073	Musa acuminata	50.00	8.40e-02	32.00
IUUC-Mpu-066394	Mustela putorius furo	77.88	3.00e-83	301.00
IUUC-Mlu-067595	Myotis lucifugus	72.73	4.00e-78	285.00
IUUC-Nle-069211	Nomascus leucogenys	76.42	1.00e-84	306.00
IUUC-Opr-070249	Ochotona princeps	68.88	4.00e-67	246.00
IUUC-Oan-073402	Ornithorhynchus anatinus	58.76	4.00e-05	40.80
IUUC-Ocu-074418	Oryctolagus cuniculus	73.93	2.00e-82	299.00
IUUC-Ogl-077238	Oryza glaberrima	26.42	9.50e-01	28.90
IUUC-Oni-082791	Oryza nivara	34.62	2.10e-01	30.40
IUUC-Opu-083378	Oryza punctata	28.30	3.80e-01	30.40
IUUC-Ola-087450	Oryzias latipes	48.78	4.00e-15	74.30
IUUC-Oga-088214	Otolemur garnettii	75.43	2.00e-84	305.00
IUUC-Oar-089324	Ovis aries	71.31	1.00e-30	127.00
IUUC-Ptr-091322	Pan troglodytes	69.31	5.00e-59	220.00
IUUC-Pan-092490	Papio anubis	76.20	4.00e-93	334.00
IUUC-Pfo-097125	Poecilia formosa	51.95	1.00e-14	73.60
IUUC-Pab-097546	Pongo abelii	85.20	3.00e-31	128.00
IUUC-Pva-102615	Pteropus vampyrus	76.54	3.00e-89	322.00
IUUC-Sha-107118	Sarcophilus harrisii	52.78	8.00e-21	94.00
IUUC-Sly-110995	Solanum lycopersicum	41.51	1.90e-02	34.30
IUUC-Stu-112004	Solanum tuberosum	41.51	2.00e-02	34.30
IUUC-Ssc-115786	Sus scrofa	77.51	4.00e-86	311.00
IUUC-Tre-122096	Trichoderma reesei	40.00	2.60e-01	29.30
IUUC-Ttr-128407	Tursiops truncatus	73.61	4.00e-79	288.00
IUUC-Xtr-131878	Xenopus tropicalis	37.81	5.00e-15	75.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence