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Tag Content
iUUCD ID IUUC-Mpu-066512
Ensembl Protein ID ENSMPUP00000010947.1
UniProt Accession M3YHZ0; M3YHZ0_MUSPF
Genbank Protein ID ENSMPUP00000010947
Protein Name Histone-lysine N-methyltransferase
Genbank Nucleotide ID AEYP01078991
Gene Name WHSC1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMPUG00000011036.1 ENSMPUT00000011129.1 ENSMPUP00000010947.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 3.30e-15 56.0 812 852
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C vC +gg+    l++Ce C  +fHp+Cl++     +p+ + w+C++Cr
   Q: 812  WCFVCSKGGS----LLCCESCPAAFHPDCLNID----MPDGS-WFCNDCR 852
           8*********....*******************....9***8.******8 PP
   
Organism Mustela putorius furo
Protein Sequence
(Fasta)
MKQAPEILGN TNGKTQNCEV NRECSVFLSK AHLSTSLQEG VMQKFNGHDA LPFIPSEKLK 60
DLTSRVFNGE PGAHDARLRF ESQEGKGLGT PPNTTPIKNG SPEIKLKITK TYMNGKPLFE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mpu-066512|E3,PHD|Mustela putorius furo
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAAAGCTGGT GCTTTCTGGG TCTCTGATTC TTCACATGTG ACCTGTTGTA TCCCCACCCC 60
ACCCCAAACC AGGTGGGTCT CCTTTGCATT TGTTATTGTT GACACTTGAT GGGTCTTTTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mpu-066512|E3,PHD|Mustela putorius furo
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR006560--AWS_dom
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51215--AWS
PS50118--HMG_BOX_2
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
PS50089--ZF_RING_2
Pfam

PF00505--HMG_box
PF00855--PWWP
PF00856--SET
SMART

SM00570--AWS
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00184--RING
SM00317--SET
Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0043565--F:sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0003289--P:atrial septum primum morphogenesis
GO:0003290--P:atrial septum secundum morphogenesis
GO:0060348--P:bone development
GO:0010452--P:histone H3-K36 methylation
GO:0034770--P:histone H4-K20 methylation
GO:0003149--P:membranous septum morphogenesis
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0048298--P:positive regulation of isotype switching to IgA isotypes
GO:2001032--P:regulation of double-strand break repair via nonhomologous end joining
GO:0070201--P:regulation of establishment of protein localization
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002181 Ailuropoda melanoleuca 97.69 0.00e+00 2558.00
IUUC-Apl-003677 Anas platyrhynchos 81.43 0.00e+00 2140.00
IUUC-Aca-004278 Anolis carolinensis 75.42 0.00e+00 1386.00
IUUC-Ame-011932 Astyanax mexicanus 71.65 0.00e+00 1035.00
IUUC-Bta-012522 Bos taurus 86.87 0.00e+00 2252.00
IUUC-Cja-018908 Callithrix jacchus 91.36 0.00e+00 2340.00
IUUC-Cfa-020894 Canis familiaris 96.59 0.00e+00 2580.00
IUUC-Cpo-021982 Cavia porcellus 88.95 0.00e+00 2343.00
IUUC-Csa-023807 Chlorocebus sabaeus 92.49 0.00e+00 2386.00
IUUC-Cho-024405 Choloepus hoffmanni 74.37 0.00e+00 743.00
IUUC-Csv-026298 Ciona savignyi 39.64 2.00e-58 219.00
IUUC-Dre-027492 Danio rerio 71.20 0.00e+00 1070.00
IUUC-Dno-030020 Dasypus novemcinctus 87.04 0.00e+00 2062.00
IUUC-Dor-031103 Dipodomys ordii 84.12 0.00e+00 2159.00
IUUC-Ete-032488 Echinops telfairi 82.70 0.00e+00 2119.00
IUUC-Eca-034066 Equus caballus 94.80 0.00e+00 2531.00
IUUC-Eeu-035199 Erinaceus europaeus 73.43 0.00e+00 778.00
IUUC-Fca-035434 Felis catus 90.09 0.00e+00 2063.00
IUUC-Fal-037113 Ficedula albicollis 79.35 0.00e+00 2143.00
IUUC-Gmo-039686 Gadus morhua 70.27 0.00e+00 1019.00
IUUC-Gga-040273 Gallus gallus 79.32 0.00e+00 2112.00
IUUC-Gac-042123 Gasterosteus aculeatus 50.98 0.00e+00 1249.00
IUUC-Ggo-044643 Gorilla gorilla 92.03 0.00e+00 2400.00
IUUC-Hsa-046380 Homo sapiens 92.32 0.00e+00 2375.00
IUUC-Itr-048658 Ictidomys tridecemlineatus 91.14 0.00e+00 1449.00
IUUC-Lch-050217 Latimeria chalumnae 66.84 0.00e+00 1736.00
IUUC-Loc-052766 Lepisosteus oculatus 58.22 0.00e+00 1280.00
IUUC-Laf-053780 Loxodonta africana 90.71 0.00e+00 2451.00
IUUC-Mcc-054928 Macaca mulatta 92.56 0.00e+00 2417.00
IUUC-Meu-056184 Macropus eugenii 74.28 0.00e+00 791.00
IUUC-Mga-059576 Meleagris gallopavo 79.83 0.00e+00 2108.00
IUUC-Mmr-061045 Microcebus murinus 92.57 0.00e+00 2469.00
IUUC-Mdo-062576 Monodelphis domestica 83.53 0.00e+00 2218.00
IUUC-Mmu-063640 Mus musculus 90.24 0.00e+00 2358.00
IUUC-Mac-065303 Musa acuminata 28.04 4.00e-11 63.20
IUUC-Mlu-067280 Myotis lucifugus 79.80 0.00e+00 1093.00
IUUC-Nle-069896 Nomascus leucogenys 92.43 0.00e+00 2291.00
IUUC-Ont-072197 Oreochromis niloticus 73.59 0.00e+00 1045.00
IUUC-Oan-072724 Ornithorhynchus anatinus 78.99 0.00e+00 1381.00
IUUC-Ocu-074758 Oryctolagus cuniculus 87.69 0.00e+00 2289.00
IUUC-Ogl-077641 Oryza glaberrima 27.33 1.00e-09 57.40
IUUC-Olo-080702 Oryza longistaminata 41.94 2.00e-45 177.00
IUUC-Opu-083371 Oryza punctata 42.31 6.00e-47 182.00
IUUC-Oga-088702 Otolemur garnettii 92.03 0.00e+00 2115.00
IUUC-Oar-089736 Ovis aries 80.59 0.00e+00 1943.00
IUUC-Ptr-091055 Pan troglodytes 92.24 0.00e+00 2373.00
IUUC-Pan-092752 Papio anubis 94.74 0.00e+00 1427.00
IUUC-Psi-093620 Pelodiscus sinensis 81.25 0.00e+00 2149.00
IUUC-Pfo-097464 Poecilia formosa 51.13 0.00e+00 1217.00
IUUC-Pab-098051 Pongo abelii 92.17 0.00e+00 2402.00
IUUC-Pop-099927 Populus trichocarpa 28.96 1.00e-11 65.50
IUUC-Pca-100273 Procavia capensis 89.57 0.00e+00 2378.00
IUUC-Pva-102473 Pteropus vampyrus 79.14 0.00e+00 1956.00
IUUC-Rno-105056 Rattus norvegicus 89.67 0.00e+00 2374.00
IUUC-Sha-107494 Sarcophilus harrisii 84.20 0.00e+00 2217.00
IUUC-Sar-113310 Sorex araneus 91.09 0.00e+00 1896.00
IUUC-Sbi-114581 Sorghum bicolor 35.19 7.00e-10 57.80
IUUC-Ssc-116344 Sus scrofa 85.76 0.00e+00 2269.00
IUUC-Tgu-116786 Taeniopygia guttata 81.10 0.00e+00 2134.00
IUUC-Tru-117638 Takifugu rubripes 50.48 0.00e+00 1250.00
IUUC-Tsy-118937 Tarsius syrichta 93.10 0.00e+00 1541.00
IUUC-Tni-120452 Tetraodon nigroviridis 53.86 0.00e+00 1170.00
IUUC-Tae-125237 Triticum aestivum 29.45 1.00e-07 49.70
IUUC-Tbe-127291 Tupaia belangeri 87.07 0.00e+00 1535.00
IUUC-Ttr-129017 Tursiops truncatus 84.51 0.00e+00 1793.00
IUUC-Xtr-132673 Xenopus tropicalis 67.58 0.00e+00 1771.00
IUUC-Xma-133695 Xiphophorus maculatus 74.20 0.00e+00 1018.00
Created Date 25-Jun-2017

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