iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ago-007788

Ensembl Protein ID

AAS50975

UniProt Accession

Q75D20; TFB3_ASHGO

Genbank Protein ID

AAS50975.1

Protein Name

RNA polymerase II transcription factor B subunit 3; RNA polymerase II transcription factor B 38 kDa subunit; RNA polymerase II transcription factor B p38 subunit

Genbank Nucleotide ID

AE016815

Gene Name

TFB3; ABR202C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AGOS_ABR202C	AAS50975	AAS50975

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	30.25	4.00e-27	119.00	IUUC-Hsa-045876
E3 activity/RING/RING	71.96	5.00e-135	475.00	IUUC-Sce-106405

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ashbya gossypii

Functional Description
(View)

Acts as component of the general transcription and DNA repair factor IIH (TFIIH or factor B), which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. TFIIH as CTD kinase activity and DNA-dependent ATPase activity, and is essential for polymerase II transcription (By similarity).

Protein Sequence
(Fasta)

MDDDEKKDMC PICKTDRYLS PDMKFLVNPE CYHKICESCV DRIFSLGPAQ CPYEGCDKIL 60
RKNKFKTQIF ADVDVEREVD IRKRVFNVFN KTIEDFDGDT AAYDQYLEEV EDIVYGLDNG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGACG ACGAGAAGAA GGACATGTGT CCTATATGTA AGACAGATCG GTATTTGTCA 60
CCGGATATGA AGTTTCTGGT GAACCCGGAG TGCTATCACA AGATATGCGA GTCCTGCGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR015877--Cdk-activating_kinase_MAT1_cen
IPR004575--MAT1/Tfb3
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF06391--MAT1
PF17121--zf-C3HC4_5

Gene Ontology

GO:0005829--C:cytosol
GO:0005675--C:holo TFIIH complex
GO:0070985--C:TFIIK complex
GO:0061575--F:cyclin-dependent protein serine/threonine kinase activator activity
GO:0008270--F:zinc ion binding
GO:0007049--P:cell cycle
GO:0006281--P:DNA repair
GO:0006289--P:nucleotide-excision repair
GO:0070816--P:phosphorylation of RNA polymerase II C-terminal domain
GO:1901409--P:positive regulation of phosphorylation of RNA polymerase II C-terminal domain
GO:0000079--P:regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0006366--P:transcription from RNA polymerase II promoter

KEGG

ago:AGOS_ABR202C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002414	Ailuropoda melanoleuca	43.06	2.00e-28	117.00
IUUC-Atr-002627	Amborella trichopoda	46.97	5.00e-11	58.50
IUUC-Apl-003312	Anas platyrhynchos	40.37	4.00e-20	89.40
IUUC-Aca-004731	Anolis carolinensis	28.21	2.00e-28	117.00
IUUC-Aly-006244	Arabidopsis lyrata	35.53	2.00e-08	49.70
IUUC-Ath-007136	Arabidopsis thaliana	34.21	5.00e-08	48.50
IUUC-Acl-008179	Aspergillus clavatus	36.92	9.00e-57	211.00
IUUC-Afl-008465	Aspergillus flavus	38.19	6.00e-59	218.00
IUUC-Afu-009056	Aspergillus fumigatus	36.34	3.00e-50	190.00
IUUC-Ani-009235	Aspergillus nidulans	28.35	3.00e-14	70.10
IUUC-Ang-009677	Aspergillus niger	37.10	8.00e-56	208.00
IUUC-Aor-010017	Aspergillus oryzae	38.40	5.00e-59	219.00
IUUC-Ate-010259	Aspergillus terreus	34.81	1.00e-50	191.00
IUUC-Ame-010934	Astyanax mexicanus	37.91	2.00e-23	100.00
IUUC-Bgr-012074	Blumeria graminis	37.30	4.00e-49	186.00
IUUC-Bta-013329	Bos taurus	43.06	2.00e-28	117.00
IUUC-Bci-013704	Botrytis cinerea	37.19	2.00e-50	190.00
IUUC-Bdi-014672	Brachypodium distachyon	40.00	5.00e-08	48.50
IUUC-Bol-015807	Brassica oleracea	35.71	8.00e-05	38.50
IUUC-Bra-017894	Brassica rapa	36.84	5.00e-10	55.10
IUUC-Cel-018428	Caenorhabditis elegans	28.36	2.00e-18	84.30
IUUC-Cja-019720	Callithrix jacchus	43.06	2.00e-28	117.00
IUUC-Cfa-020319	Canis familiaris	43.06	2.00e-28	117.00
IUUC-Cpo-021652	Cavia porcellus	29.69	4.00e-29	119.00
IUUC-Cre-022749	Chlamydomonas reinhardtii	38.57	5.00e-12	62.00
IUUC-Csa-023560	Chlorocebus sabaeus	29.38	7.00e-29	118.00
IUUC-Cho-024753	Choloepus hoffmanni	30.30	1.00e-03	35.80
IUUC-Cin-025502	Ciona intestinalis	29.21	2.00e-29	120.00
IUUC-Csv-026302	Ciona savignyi	34.27	1.00e-30	124.00
IUUC-Cgl-026541	Colletotrichum gloeosporioides	60.61	1.00e-10	57.80
IUUC-Cne-027055	Cryptococcus neoformans	44.44	9.00e-35	138.00
IUUC-Cme-027128	Cyanidioschyzon merolae	41.07	2.00e-06	43.50
IUUC-Dre-027714	Danio rerio	43.62	3.00e-28	116.00
IUUC-Dno-029232	Dasypus novemcinctus	43.70	3.00e-28	115.00
IUUC-Dor-030996	Dipodomys ordii	44.87	8.00e-12	61.60
IUUC-Dse-031359	Dothistroma septosporum	37.27	4.00e-49	186.00
IUUC-Dme-031992	Drosophila melanogaster	44.90	1.00e-29	121.00
IUUC-Ete-032973	Echinops telfairi	39.29	3.00e-05	40.40
IUUC-Eca-034116	Equus caballus	43.06	2.00e-28	117.00
IUUC-Eeu-035143	Erinaceus europaeus	33.33	1.00e-16	78.20
IUUC-Fca-035960	Felis catus	43.06	2.00e-28	117.00
IUUC-Fal-037039	Ficedula albicollis	41.28	4.00e-20	89.00
IUUC-Fox-037882	Fusarium oxysporum	37.58	5.00e-43	166.00
IUUC-Fso-038318	Fusarium solani	36.79	3.00e-48	183.00
IUUC-Gmo-038905	Gadus morhua	41.18	2.00e-26	110.00
IUUC-Ggr-039857	Gaeumannomyces graminis	44.44	1.00e-22	98.20
IUUC-Gga-041216	Gallus gallus	41.48	2.00e-27	114.00
IUUC-Gac-041987	Gasterosteus aculeatus	41.38	1.00e-25	107.00
IUUC-Gma-044312	Glycine max	42.65	5.00e-10	55.10
IUUC-Ggo-044930	Gorilla gorilla	41.38	7.00e-19	85.50
IUUC-Hsa-045876	Homo sapiens	29.38	7.00e-29	118.00
IUUC-Hvu-047088	Hordeum vulgare	40.00	4.00e-08	48.90
IUUC-Itr-048476	Ictidomys tridecemlineatus	42.98	4.00e-23	99.00
IUUC-Kpa-049202	Komagataella pastoris	43.12	7.00e-62	228.00
IUUC-Lch-049886	Latimeria chalumnae	41.48	1.00e-25	108.00
IUUC-Lpe-051199	Leersia perrieri	40.28	3.00e-08	49.30
IUUC-Loc-052556	Lepisosteus oculatus	40.97	9.00e-27	111.00
IUUC-Lma-053002	Leptosphaeria maculans	35.46	3.00e-45	173.00
IUUC-Laf-054516	Loxodonta africana	43.06	2.00e-28	117.00
IUUC-Mcc-054761	Macaca mulatta	43.06	2.00e-28	117.00
IUUC-Meu-056782	Macropus eugenii	30.30	2.00e-03	35.00
IUUC-Mor-057048	Magnaporthe oryzae	31.66	6.00e-32	129.00
IUUC-Mpo-057598	Magnaporthe poae	46.61	3.00e-20	89.00
IUUC-Mtr-058131	Medicago truncatula	44.12	1.00e-10	57.00
IUUC-Mla-059009	Melampsora laricipopulina	55.56	4.00e-39	151.00
IUUC-Mga-060199	Meleagris gallopavo	40.37	4.00e-20	88.60
IUUC-Mvi-060382	Microbotryum violaceum	34.80	5.00e-37	145.00
IUUC-Mmr-061671	Microcebus murinus	43.06	4.00e-28	115.00
IUUC-Mdo-062228	Monodelphis domestica	29.06	1.00e-27	114.00
IUUC-Mmu-064416	Mus musculus	43.06	1.00e-28	117.00
IUUC-Mac-064807	Musa acuminata	45.45	2.00e-09	53.10
IUUC-Mpu-066455	Mustela putorius furo	43.06	2.00e-28	117.00
IUUC-Mlu-067325	Myotis lucifugus	42.98	1.00e-22	97.10
IUUC-Nfi-068566	Neosartorya fischeri	35.67	2.00e-52	197.00
IUUC-Ncr-068687	Neurospora crassa	30.82	2.00e-39	153.00
IUUC-Nle-069937	Nomascus leucogenys	29.38	7.00e-29	118.00
IUUC-Opr-070321	Ochotona princeps	45.35	4.00e-18	83.20
IUUC-Ont-072636	Oreochromis niloticus	42.55	8.00e-27	111.00
IUUC-Oan-072915	Ornithorhynchus anatinus	39.45	1.00e-17	80.50
IUUC-Ocu-074547	Oryctolagus cuniculus	45.53	8.00e-26	108.00
IUUC-Oba-075269	Oryza barthii	43.08	8.00e-09	51.20
IUUC-Obr-076081	Oryza brachyantha	40.00	4.00e-08	48.90
IUUC-Ogl-077011	Oryza glaberrima	43.08	8.00e-09	51.20
IUUC-Ogu-078667	Oryza glumaepatula	43.08	7.00e-09	51.20
IUUC-Oin-079153	Oryza indica	43.08	8.00e-09	51.20
IUUC-Olo-080344	Oryza longistaminata	43.33	8.00e-06	41.20
IUUC-Ome-081805	Oryza meridionalis	40.28	4.00e-08	49.30
IUUC-Oni-082783	Oryza nivara	41.54	4.00e-08	48.90
IUUC-Opu-083247	Oryza punctata	41.54	1.00e-08	50.40
IUUC-Oru-085262	Oryza rufipogon	41.67	8.00e-09	51.20
IUUC-Osa-086250	Oryza sativa	41.67	8.00e-09	51.20
IUUC-Ola-086780	Oryzias latipes	41.45	7.00e-27	112.00
IUUC-Olu-087653	Ostreococcus lucimarinus	29.85	2.00e-05	40.00
IUUC-Oga-088012	Otolemur garnettii	43.06	7.00e-28	115.00
IUUC-Oar-090274	Ovis aries	36.30	5.00e-19	85.90
IUUC-Ptr-090780	Pan troglodytes	29.38	7.00e-29	118.00
IUUC-Pan-091815	Papio anubis	37.80	4.00e-18	82.40
IUUC-Psi-093883	Pelodiscus sinensis	42.22	2.00e-28	117.00
IUUC-Pma-094717	Petromyzon marinus	40.91	9.00e-09	51.60
IUUC-Pno-094958	Phaeosphaeria nodorum	34.82	7.00e-44	168.00
IUUC-Ppa-095445	Physcomitrella patens	46.88	9.00e-12	60.80
IUUC-Pfo-096051	Poecilia formosa	42.28	3.00e-27	113.00
IUUC-Pab-097609	Pongo abelii	43.70	3.00e-28	116.00
IUUC-Pop-099460	Populus trichocarpa	25.11	8.00e-13	64.70
IUUC-Pca-101094	Procavia capensis	44.04	5.00e-21	92.40
IUUC-Ppe-101481	Prunus persica	44.12	2.00e-10	56.60
IUUC-Pva-103219	Pteropus vampyrus	43.06	4.00e-28	116.00
IUUC-Pgr-103557	Puccinia graminis	53.96	4.00e-40	156.00
IUUC-Ptt-103719	Puccinia triticina	54.35	9.00e-40	155.00
IUUC-Pte-104301	Pyrenophora teres	27.33	3.00e-31	126.00
IUUC-Pyt-104486	Pyrenophora triticirepentis	43.38	5.00e-31	125.00
IUUC-Rno-105846	Rattus norvegicus	43.06	1.00e-28	117.00
IUUC-Sce-106405	Saccharomyces cerevisiae	71.96	2.00e-122	429.00
IUUC-Sha-107594	Sarcophilus harrisii	42.20	2.00e-19	86.30
IUUC-Sja-107951	Schizosaccharomyces japonicus	37.62	3.00e-48	182.00
IUUC-Spo-108137	Schizosaccharomyces pombe	38.26	2.00e-46	177.00
IUUC-Ssl-108503	Sclerotinia sclerotiorum	38.15	1.00e-56	211.00
IUUC-Smo-108895	Selaginella moellendorffii	36.36	4.00e-11	58.50
IUUC-Sit-110672	Setaria italica	40.28	2.00e-08	50.10
IUUC-Sly-111744	Solanum lycopersicum	42.42	3.00e-09	52.40
IUUC-Stu-112343	Solanum tuberosum	42.42	1.00e-09	53.50
IUUC-Sar-113298	Sorex araneus	44.44	6.00e-29	118.00
IUUC-Sbi-113918	Sorghum bicolor	43.08	8.00e-09	51.20
IUUC-Sre-114991	Sporisorium reilianum	48.95	2.00e-30	124.00
IUUC-Ssc-116152	Sus scrofa	43.12	5.00e-21	91.70
IUUC-Tgu-116452	Taeniopygia guttata	42.22	2.00e-27	114.00
IUUC-Tru-118621	Takifugu rubripes	41.06	5.00e-25	105.00
IUUC-Tsy-119500	Tarsius syrichta	42.36	1.00e-27	114.00
IUUC-Tni-120454	Tetraodon nigroviridis	36.97	1.00e-14	71.20
IUUC-Tca-121192	Theobroma cacao	42.11	5.00e-11	58.50
IUUC-Tre-122011	Trichoderma reesei	35.09	2.00e-42	164.00
IUUC-Tvi-122317	Trichoderma virens	36.14	7.00e-48	182.00
IUUC-Tae-123854	Triticum aestivum	40.00	3.00e-08	49.30
IUUC-Tur-126556	Triticum urartu	40.00	4.00e-08	48.90
IUUC-Tme-127135	Tuber melanosporum	41.42	2.00e-42	163.00
IUUC-Tbe-127287	Tupaia belangeri	27.37	2.00e-17	80.90
IUUC-Ttr-128864	Tursiops truncatus	43.06	2.00e-28	117.00
IUUC-Uma-129539	Ustilago maydis	53.17	1.00e-33	135.00
IUUC-Vda-129713	Verticillium dahliae	36.16	1.00e-36	144.00
IUUC-Vpa-130462	Vicugna pacos	38.19	3.00e-20	89.70
IUUC-Vvi-130988	Vitis vinifera	42.65	3.00e-09	52.80
IUUC-Xtr-131830	Xenopus tropicalis	39.26	3.00e-26	109.00
IUUC-Xma-133952	Xiphophorus maculatus	42.95	1.00e-27	114.00
IUUC-Yli-134433	Yarrowia lipolytica	42.45	1.00e-62	231.00
IUUC-Zma-134867	Zea mays	41.54	2.00e-08	50.10

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence