iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005078

UUCD1 version

UUC-AnC-00795

Ensembl Protein ID

ENSACAP00000014494.3

UniProt Accession

G1KQ96; G1KQ96_ANOCA

Protein Name

Uncharacterized protein

Gene Name

RFWD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000014695.3	ENSACAT00000014789.3	ENSACAP00000014494.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.20e-24	83.0	518	547
E3 activity/RING/RING	2.10e-06	28.1	188	226

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 3    tdsvtclaf..sd.tllvsGsdDgtikvWD 29
           +++++c+++     +ll+s+ + gt+ +WD
   Q: 518  NSKISCISWssYHkNLLASSDYEGTVILWD 547
           689******9622599************** PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC++++++  + + CgH f+ +C+++          + rCP C+
   Q: 188  CPICFDMIEE-AYMTKCGHSFCYKCIHQS------LEDNNRCPKCN 226
           ********99.888***********9555......999999****6 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MRMRRASPEE RGRCLEPSPR PFGLRASTGA NQVPRTRSGA GACPPSSERK LSCGPLPSRS 60
AGAGMSGSRQ PPQHSAAGPP PPGSSSPSVT TSASSATAAA APGASSSSSS ASVGLGAPAR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCGCATGC GCAGGGCCAG CCCGGAGGAG AGGGGAAGGT GTTTGGAGCC TTCGCCCCGC 60
CCCTTCGGTT TGAGAGCGAG CACAGGGGCC AATCAGGTGC CGCGCACGCG CTCCGGGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00400--WD40

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0010212--P:response to ionizing radiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000885	Aegilops tauschii	39.19	9.00e-122	430.00
IUUC-Aml-001265	Ailuropoda melanoleuca	97.73	0.00e+00	1209.00
IUUC-Atr-002460	Amborella trichopoda	38.76	4.00e-125	441.00
IUUC-Apl-003796	Anas platyrhynchos	97.42	0.00e+00	1127.00
IUUC-Aly-006014	Arabidopsis lyrata	39.66	9.00e-129	453.00
IUUC-Ath-007636	Arabidopsis thaliana	39.04	6.00e-129	454.00
IUUC-Ame-011176	Astyanax mexicanus	74.73	1.00e-69	257.00
IUUC-Bta-012595	Bos taurus	97.58	0.00e+00	1212.00
IUUC-Bdi-014152	Brachypodium distachyon	39.69	8.00e-127	447.00
IUUC-Bol-016380	Brassica oleracea	40.43	7.00e-130	457.00
IUUC-Bra-017690	Brassica rapa	38.96	2.00e-121	429.00
IUUC-Cja-018926	Callithrix jacchus	97.42	0.00e+00	1211.00
IUUC-Cfa-021088	Canis familiaris	97.26	0.00e+00	1211.00
IUUC-Cpo-022442	Cavia porcellus	96.55	0.00e+00	1171.00
IUUC-Cre-022579	Chlamydomonas reinhardtii	33.45	4.00e-33	134.00
IUUC-Csa-024119	Chlorocebus sabaeus	97.26	0.00e+00	1209.00
IUUC-Cho-024883	Choloepus hoffmanni	66.23	1.00e-105	377.00
IUUC-Cin-025375	Ciona intestinalis	56.22	0.00e+00	685.00
IUUC-Cme-027350	Cyanidioschyzon merolae	40.78	7.00e-80	291.00
IUUC-Dre-028453	Danio rerio	87.80	0.00e+00	1085.00
IUUC-Dno-029887	Dasypus novemcinctus	97.26	0.00e+00	1209.00
IUUC-Dor-031110	Dipodomys ordii	88.89	0.00e+00	852.00
IUUC-Ete-033016	Echinops telfairi	83.41	0.00e+00	1014.00
IUUC-Eca-034403	Equus caballus	97.23	0.00e+00	1121.00
IUUC-Eeu-034690	Erinaceus europaeus	80.84	0.00e+00	930.00
IUUC-Fca-036475	Felis catus	96.90	0.00e+00	1125.00
IUUC-Fal-037189	Ficedula albicollis	97.99	0.00e+00	1164.00
IUUC-Gmo-039245	Gadus morhua	86.42	0.00e+00	1051.00
IUUC-Gga-040806	Gallus gallus	98.06	0.00e+00	1213.00
IUUC-Gac-042177	Gasterosteus aculeatus	87.52	0.00e+00	1090.00
IUUC-Gma-044187	Glycine max	38.85	2.00e-125	442.00
IUUC-Ggo-044430	Gorilla gorilla	95.97	0.00e+00	893.00
IUUC-Hsa-045853	Homo sapiens	97.42	0.00e+00	1211.00
IUUC-Hvu-047750	Hordeum vulgare	38.87	9.00e-96	345.00
IUUC-Itr-048238	Ictidomys tridecemlineatus	98.75	2.00e-144	503.00
IUUC-Lch-050420	Latimeria chalumnae	92.47	0.00e+00	1142.00
IUUC-Lpe-051219	Leersia perrieri	37.31	1.00e-118	420.00
IUUC-Loc-052728	Lepisosteus oculatus	91.23	0.00e+00	1092.00
IUUC-Laf-053775	Loxodonta africana	96.76	0.00e+00	1207.00
IUUC-Meu-056595	Macropus eugenii	77.73	2.00e-177	615.00
IUUC-Mtr-058555	Medicago truncatula	40.93	1.00e-132	466.00
IUUC-Mga-059646	Meleagris gallopavo	97.08	0.00e+00	1126.00
IUUC-Mmr-060990	Microcebus murinus	97.73	0.00e+00	1209.00
IUUC-Mdo-062287	Monodelphis domestica	97.91	0.00e+00	1217.00
IUUC-Mmu-064097	Mus musculus	97.58	0.00e+00	1214.00
IUUC-Mac-065240	Musa acuminata	41.41	4.00e-134	471.00
IUUC-Mpu-066612	Mustela putorius furo	96.91	0.00e+00	1130.00
IUUC-Mlu-067967	Myotis lucifugus	95.14	0.00e+00	1129.00
IUUC-Nle-069543	Nomascus leucogenys	97.58	0.00e+00	1214.00
IUUC-Opr-070366	Ochotona princeps	81.78	0.00e+00	695.00
IUUC-Ont-071522	Oreochromis niloticus	88.08	0.00e+00	1093.00
IUUC-Oan-073409	Ornithorhynchus anatinus	97.42	0.00e+00	1128.00
IUUC-Ocu-073756	Oryctolagus cuniculus	97.67	0.00e+00	1181.00
IUUC-Oba-075149	Oryza barthii	38.10	3.00e-123	436.00
IUUC-Obr-076563	Oryza brachyantha	37.84	2.00e-121	429.00
IUUC-Ogl-077701	Oryza glaberrima	38.13	9.00e-124	437.00
IUUC-Ogu-078383	Oryza glumaepatula	38.13	9.00e-124	437.00
IUUC-Oin-079965	Oryza indica	36.07	8.00e-110	390.00
IUUC-Olo-080639	Oryza longistaminata	38.45	2.00e-123	436.00
IUUC-Ome-081821	Oryza meridionalis	37.80	7.00e-114	405.00
IUUC-Oni-082622	Oryza nivara	38.13	9.00e-124	437.00
IUUC-Opu-083295	Oryza punctata	38.13	1.00e-123	436.00
IUUC-Oru-084661	Oryza rufipogon	38.13	9.00e-124	437.00
IUUC-Osa-085766	Oryza sativa	38.13	9.00e-124	437.00
IUUC-Ola-086727	Oryzias latipes	87.18	0.00e+00	1086.00
IUUC-Olu-087702	Ostreococcus lucimarinus	42.86	6.00e-69	253.00
IUUC-Oga-088215	Otolemur garnettii	95.48	0.00e+00	1184.00
IUUC-Oar-089880	Ovis aries	97.51	0.00e+00	1179.00
IUUC-Ptr-090597	Pan troglodytes	97.42	0.00e+00	1211.00
IUUC-Pan-091987	Papio anubis	97.75	0.00e+00	1216.00
IUUC-Psi-094033	Pelodiscus sinensis	99.15	0.00e+00	1163.00
IUUC-Pma-094587	Petromyzon marinus	71.07	0.00e+00	806.00
IUUC-Ppa-095256	Physcomitrella patens	38.44	8.00e-130	457.00
IUUC-Pfo-097388	Poecilia formosa	87.08	0.00e+00	1071.00
IUUC-Pab-098029	Pongo abelii	97.42	0.00e+00	1211.00
IUUC-Pop-099319	Populus trichocarpa	38.94	3.00e-129	455.00
IUUC-Pca-100846	Procavia capensis	89.21	0.00e+00	1118.00
IUUC-Ppe-101250	Prunus persica	38.07	3.00e-118	418.00
IUUC-Pva-102407	Pteropus vampyrus	97.42	0.00e+00	1201.00
IUUC-Rno-105312	Rattus norvegicus	97.42	0.00e+00	1211.00
IUUC-Sha-106514	Sarcophilus harrisii	98.92	0.00e+00	779.00
IUUC-Smo-109418	Selaginella moellendorffii	38.71	3.00e-124	439.00
IUUC-Sit-110248	Setaria italica	38.23	3.00e-125	442.00
IUUC-Sly-110964	Solanum lycopersicum	40.43	3.00e-129	455.00
IUUC-Stu-112882	Solanum tuberosum	40.68	2.00e-130	459.00
IUUC-Sar-113230	Sorex araneus	71.86	0.00e+00	794.00
IUUC-Sbi-113962	Sorghum bicolor	36.39	3.00e-119	422.00
IUUC-Ssc-115987	Sus scrofa	95.56	4.00e-166	577.00
IUUC-Tgu-116471	Taeniopygia guttata	97.73	0.00e+00	1206.00
IUUC-Tru-118231	Takifugu rubripes	88.42	0.00e+00	1061.00
IUUC-Tsy-119415	Tarsius syrichta	96.97	0.00e+00	1135.00
IUUC-Tni-120893	Tetraodon nigroviridis	87.52	0.00e+00	1055.00
IUUC-Tca-121703	Theobroma cacao	40.68	5.00e-128	451.00
IUUC-Tae-125440	Triticum aestivum	40.61	4.00e-132	464.00
IUUC-Tur-126557	Triticum urartu	40.31	5.00e-126	444.00
IUUC-Tbe-127253	Tupaia belangeri	69.73	0.00e+00	829.00
IUUC-Ttr-129100	Tursiops truncatus	95.63	0.00e+00	1105.00
IUUC-Vpa-130613	Vicugna pacos	90.92	0.00e+00	1061.00
IUUC-Vvi-130880	Vitis vinifera	40.91	3.00e-121	428.00
IUUC-Xtr-132033	Xenopus tropicalis	96.27	0.00e+00	1226.00
IUUC-Xma-133421	Xiphophorus maculatus	86.91	0.00e+00	1070.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence