iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-007401

UUCD1 version

UUC-ArT-00305

Ensembl Protein ID

AT2G23780.3

UniProt Accession

O64824; O64824_ARATH

Genbank Protein ID

AAC17085.1; AAP40387.1; AAP40507.1; AEC07490.1; ANM61882.1; ANM61883.1; BAF01369.1

Protein Name

Putative RING zinc finger protein; RING/U-box superfamily protein

Genbank Nucleotide ID

AC004482; BT008560; BT008701; CP002685; CP002685; CP002685; AK229514

Gene Name

At2g23780; F27L4.4; F27L4_4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT2G23780	AT2G23780.3	AT2G23780.3

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
HINT
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.80e-06	28.8	25	80
E3 activity/RING/RING	1.10e-06	29.9	28	69

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlpsGitydrssIekwlasggk..tcPvtrqplteedlvPn 58
           +f C I +el +dP v+ +G+ +   ++ +wl +  +  +cPv+++ +++++lvP 
   Q: 25   DFECNICFELAQDPIVTLCGHLFCWPCLYRWLHHHSHsqECPVCKAVVQDDKLVPL 80
           699*****************************65555579**************96 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC+e  +d p+v+ CgH+f+  Cl++w +++   s ++ CP+C+
   Q: 28   CNICFELAQD-PIVTLCGHLFCWPCLYRW-LHH--HSHSQECPVCK 69
           99********.999***************.555..788899****7 PP

Organism

Arabidopsis thaliana

Protein Sequence
(Fasta)

MVNGESSTST SYSDSNNDTN DQGGDFECNI CFELAQDPIV TLCGHLFCWP CLYRWLHHHS 60
HSQECPVCKA VVQDDKLVPL YGRGKNQTDP RSKRYPGLRI PNRPTGQRPE TAAPPPQPEA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGAAAAAAA ACGAGAAAAA CCAAAAGTCA GATATAGCCT GGAACTTTCT TTCCCAACAA 60
CAGTAAGACT CTGTTTTTTC CCAAGATGTC TGGTTTCCTC TTTTGTTTCG TCCAAATCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0016021--C:integral component of membrane
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0044390--F:ubiquitin-like protein conjugating enzyme binding
GO:0008270--F:zinc ion binding
GO:0071712--P:ER-associated misfolded protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001875	Ailuropoda melanoleuca	57.53	3.00e-23	100.00
IUUC-Aca-004254	Anolis carolinensis	53.16	9.00e-23	98.60
IUUC-Aly-005785	Arabidopsis lyrata	94.27	2.00e-94	337.00
IUUC-Bta-012734	Bos taurus	57.53	4.00e-23	100.00
IUUC-Bol-016132	Brassica oleracea	80.19	5.00e-92	329.00
IUUC-Bra-017631	Brassica rapa	78.50	9.00e-92	328.00
IUUC-Cel-018228	Caenorhabditis elegans	38.67	7.00e-28	116.00
IUUC-Cja-019136	Callithrix jacchus	57.53	3.00e-23	100.00
IUUC-Cfa-020308	Canis familiaris	57.53	3.00e-23	100.00
IUUC-Cpo-021347	Cavia porcellus	57.53	3.00e-23	100.00
IUUC-Csa-023755	Chlorocebus sabaeus	57.53	2.00e-23	100.00
IUUC-Cme-027164	Cyanidioschyzon merolae	53.85	6.00e-20	90.50
IUUC-Dno-029402	Dasypus novemcinctus	57.53	3.00e-23	100.00
IUUC-Dor-030170	Dipodomys ordii	56.47	7.00e-25	105.00
IUUC-Ete-032786	Echinops telfairi	57.53	2.00e-23	100.00
IUUC-Eca-034261	Equus caballus	57.53	3.00e-23	100.00
IUUC-Fca-036049	Felis catus	57.53	3.00e-23	100.00
IUUC-Fal-037085	Ficedula albicollis	56.76	4.00e-23	100.00
IUUC-Gmo-039369	Gadus morhua	53.62	7.00e-22	95.90
IUUC-Gga-040514	Gallus gallus	57.53	5.00e-23	100.00
IUUC-Gac-041719	Gasterosteus aculeatus	55.07	1.00e-21	95.50
IUUC-Gma-043248	Glycine max	64.25	1.00e-71	261.00
IUUC-Ggo-044504	Gorilla gorilla	57.53	3.00e-23	100.00
IUUC-Hsa-045707	Homo sapiens	57.53	3.00e-23	100.00
IUUC-Itr-048343	Ictidomys tridecemlineatus	57.53	3.00e-23	100.00
IUUC-Kpa-049131	Komagataella pastoris	31.46	6.00e-09	55.10
IUUC-Lch-050658	Latimeria chalumnae	57.53	5.00e-23	100.00
IUUC-Lpe-050977	Leersia perrieri	51.92	8.00e-50	189.00
IUUC-Loc-052118	Lepisosteus oculatus	55.22	2.00e-21	94.70
IUUC-Laf-054438	Loxodonta africana	57.53	3.00e-23	100.00
IUUC-Mcc-054833	Macaca mulatta	55.29	1.00e-24	105.00
IUUC-Meu-055984	Macropus eugenii	52.56	2.00e-20	90.90
IUUC-Mtr-058107	Medicago truncatula	60.48	1.00e-62	232.00
IUUC-Mga-059554	Meleagris gallopavo	57.53	5.00e-23	100.00
IUUC-Mmr-061662	Microcebus murinus	47.37	5.00e-15	73.20
IUUC-Mdo-062437	Monodelphis domestica	52.63	7.00e-27	112.00
IUUC-Mmu-063372	Mus musculus	57.53	8.00e-23	99.40
IUUC-Mlu-067254	Myotis lucifugus	57.53	3.00e-23	100.00
IUUC-Nle-069850	Nomascus leucogenys	57.53	3.00e-23	100.00
IUUC-Opr-070197	Ochotona princeps	57.14	8.00e-22	95.90
IUUC-Oan-073480	Ornithorhynchus anatinus	57.53	3.00e-23	100.00
IUUC-Ocu-074208	Oryctolagus cuniculus	54.12	3.00e-24	103.00
IUUC-Oba-075461	Oryza barthii	50.22	5.00e-49	187.00
IUUC-Obr-076749	Oryza brachyantha	61.59	7.00e-47	179.00
IUUC-Ogl-077129	Oryza glaberrima	50.22	7.00e-49	186.00
IUUC-Ogu-078727	Oryza glumaepatula	50.00	2.00e-48	184.00
IUUC-Oin-079194	Oryza indica	49.78	5.00e-49	186.00
IUUC-Olo-080653	Oryza longistaminata	50.00	2.00e-48	184.00
IUUC-Ome-081636	Oryza meridionalis	50.00	2.00e-48	185.00
IUUC-Oni-082546	Oryza nivara	49.78	3.00e-49	187.00
IUUC-Opu-083228	Oryza punctata	52.38	2.00e-47	181.00
IUUC-Oru-084914	Oryza rufipogon	50.22	5.00e-49	187.00
IUUC-Osa-086216	Oryza sativa	50.22	7.00e-49	186.00
IUUC-Oga-088197	Otolemur garnettii	54.55	2.00e-23	101.00
IUUC-Oar-090284	Ovis aries	54.12	4.00e-24	103.00
IUUC-Ptr-091106	Pan troglodytes	57.53	3.00e-23	100.00
IUUC-Pan-092671	Papio anubis	57.53	2.00e-23	100.00
IUUC-Psi-093323	Pelodiscus sinensis	57.53	4.00e-23	100.00
IUUC-Ppa-095474	Physcomitrella patens	59.48	5.00e-48	183.00
IUUC-Pab-097845	Pongo abelii	57.53	3.00e-23	100.00
IUUC-Pop-098988	Populus trichocarpa	58.72	2.00e-63	234.00
IUUC-Pca-100319	Procavia capensis	55.29	6.00e-25	106.00
IUUC-Ppe-102011	Prunus persica	60.85	2.00e-68	251.00
IUUC-Pva-102249	Pteropus vampyrus	38.51	1.00e-25	108.00
IUUC-Rno-105293	Rattus norvegicus	57.53	2.00e-23	101.00
IUUC-Sha-107361	Sarcophilus harrisii	57.53	2.00e-23	101.00
IUUC-Sar-113669	Sorex araneus	56.52	2.00e-11	59.30
IUUC-Sbi-114275	Sorghum bicolor	52.88	4.00e-49	186.00
IUUC-Ssc-116228	Sus scrofa	57.53	3.00e-23	100.00
IUUC-Tgu-116886	Taeniopygia guttata	56.76	4.00e-23	100.00
IUUC-Tsy-119615	Tarsius syrichta	54.55	9.00e-26	108.00
IUUC-Tni-120909	Tetraodon nigroviridis	54.55	5.00e-24	103.00
IUUC-Tca-121830	Theobroma cacao	68.25	4.00e-78	283.00
IUUC-Tbe-127360	Tupaia belangeri	57.53	5.00e-23	99.80
IUUC-Ttr-129044	Tursiops truncatus	57.53	3.00e-23	100.00
IUUC-Vpa-130365	Vicugna pacos	56.16	3.00e-22	97.40
IUUC-Xtr-132608	Xenopus tropicalis	57.97	4.00e-23	99.80

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence