iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011813

Ensembl Protein ID

ENSAMXP00000002885.1

UniProt Accession

W5K5M4; W5K5M4_ASTMX

Genbank Protein ID

ENSAMXP00000002885

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01114592

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000002823.1	ENSAMXT00000002885.1	ENSAMXP00000002885.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	5.80e-47	160.8	113	310

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C++Cl++++ ++l  l+ C+h+ C  Cl+qyl+++i e++ +++scp  ec e+l +++++ +l ++ l ++ye++ll++++++d++++w
   Q: 113  CPLCLVRQPRDQLAELQGCSHRSCLCCLRQYLRIEITESR-VQLSCP--ECAERLAPRQVALILDDPALLEKYEEFLLRRCLASDPDCRW 199
           ****************************************.99****..89*************************************** PP
   S: 91   cpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeek....eeaeskelleanskkCpkCkvyiek. 173
           cpapdC ++v+++ +a  ++l +++e+cg efC++Ck++wH++++C+++++++a + +++     +++ ++  ++++k+Cp+C +yi+k 
   Q: 200  CPAPDCGFAVIASGCAscPRLVCRREGCGAEFCYHCKQAWHPNQTCDSARQQRALSLRTHsthsPSYTAEQGPTDDIKPCPRCGAYIIKm 289
           **************9988999*******************************999888776665556677778899************99 PP
   S: 174  .negCnhmtCakCkaefCwlC 193
            +++CnhmtCa C++efCwlC
   Q: 290  nDGSCNHMTCAVCGCEFCWLC 310
           7889***************** PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MGSEKDSESP HSSVSGIPNP KCRGPGKKQN RISFSSLFHS KRSSRGSKAS VGTPSQQLHQ 60
QQQLQQQQQQ QQQLLQPSTP TANASPDPPT TGDSAEPLSS SQASLGGQDL LECPLCLVRQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGGCCGAT TCAGAAAGGA GAGTGGAACA AACTGGAGCA GCTCGGCTCA GTGTAACCTG 60
GAGAATACAG CTGCGGGAAT AGAGGACATT AGCAGCAAAC AAGCCTCCTG AAAGCATCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002183	Ailuropoda melanoleuca	66.37	0.00e+00	667.00
IUUC-Aca-004324	Anolis carolinensis	67.69	0.00e+00	692.00
IUUC-Bta-013135	Bos taurus	61.25	0.00e+00	723.00
IUUC-Cja-019264	Callithrix jacchus	64.35	0.00e+00	653.00
IUUC-Cpo-022502	Cavia porcellus	68.97	0.00e+00	630.00
IUUC-Cho-025032	Choloepus hoffmanni	62.71	1.00e-146	513.00
IUUC-Cin-025143	Ciona intestinalis	63.64	7.00e-40	156.00
IUUC-Dre-028769	Danio rerio	90.11	0.00e+00	1167.00
IUUC-Ete-033008	Echinops telfairi	82.75	9.00e-123	433.00
IUUC-Gac-041619	Gasterosteus aculeatus	86.80	0.00e+00	919.00
IUUC-Hsa-045958	Homo sapiens	67.76	0.00e+00	716.00
IUUC-Lch-049552	Latimeria chalumnae	63.46	0.00e+00	768.00
IUUC-Loc-051738	Lepisosteus oculatus	79.57	0.00e+00	875.00
IUUC-Meu-055920	Macropus eugenii	69.20	0.00e+00	640.00
IUUC-Mdo-061985	Monodelphis domestica	59.97	0.00e+00	725.00
IUUC-Mmu-064262	Mus musculus	67.13	0.00e+00	710.00
IUUC-Mpu-066101	Mustela putorius furo	68.08	0.00e+00	708.00
IUUC-Oan-073219	Ornithorhynchus anatinus	68.74	7.00e-170	590.00
IUUC-Ola-086499	Oryzias latipes	87.76	0.00e+00	961.00
IUUC-Oga-088812	Otolemur garnettii	68.60	0.00e+00	688.00
IUUC-Oar-090353	Ovis aries	68.60	0.00e+00	629.00
IUUC-Pfo-096268	Poecilia formosa	87.58	0.00e+00	1003.00
IUUC-Pab-098031	Pongo abelii	28.67	3.00e-19	89.00
IUUC-Pva-102542	Pteropus vampyrus	83.80	5.00e-141	494.00
IUUC-Sha-106512	Sarcophilus harrisii	68.14	0.00e+00	708.00
IUUC-Ssl-108396	Sclerotinia sclerotiorum	25.58	7.00e-09	56.20
IUUC-Sar-113233	Sorex araneus	67.57	7.00e-161	560.00
IUUC-Ssc-115781	Sus scrofa	66.55	0.00e+00	736.00
IUUC-Tru-117919	Takifugu rubripes	86.87	0.00e+00	942.00
IUUC-Tsy-119275	Tarsius syrichta	65.36	1.00e-168	586.00
IUUC-Tbe-127335	Tupaia belangeri	75.41	5.00e-146	510.00
IUUC-Vpa-130407	Vicugna pacos	62.72	1.00e-166	579.00
IUUC-Xtr-132325	Xenopus tropicalis	72.30	4.00e-175	607.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence