iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-073779

Ensembl Protein ID

ENSOCUP00000008968.3

UniProt Accession

G1SZ84; G1SZ84_RABIT

Protein Name

Inhibitor of growth protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000010414.3	ENSOCUT00000010411.3	ENSOCUP00000008968.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.80e-09	36.6	174	221

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 174  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 221
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MTLPATCNEI LKELDDYYEK FKREADGTQK RRVLHCIQRA LIRSQELGDE KIQIVSQMVE 60
LVENRSRQVD SHVALLEAHQ DAGDAAGSSG KAGQEKSKSE TVTQAEKPNN KRSRRQRNNE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGAGAGTGGA GCAGCGGGGA CTTGAACGCG GGCTTCCCAG CCTCACCCCC TGTGCCACGG 60
CAGCGCATCC CAGTAACTTC AGTCACTTCA GAGGGCGTTC CAGGTTGCTG AACCCACTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006606--P:protein import into nucleus
GO:0010941--P:regulation of cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	89.58	1.00e-101	362.00
IUUC-Apl-003910	Anas platyrhynchos	87.45	8.00e-97	346.00
IUUC-Aca-004874	Anolis carolinensis	87.50	6.00e-97	347.00
IUUC-Ame-011262	Astyanax mexicanus	67.35	6.00e-76	276.00
IUUC-Bta-013507	Bos taurus	88.46	1.00e-91	328.00
IUUC-Cja-018925	Callithrix jacchus	85.83	3.00e-95	341.00
IUUC-Cfa-020947	Canis familiaris	89.17	3.00e-100	357.00
IUUC-Cpo-022286	Cavia porcellus	87.04	2.00e-98	352.00
IUUC-Csa-023825	Chlorocebus sabaeus	85.42	7.00e-95	340.00
IUUC-Cho-024577	Choloepus hoffmanni	91.42	1.00e-99	355.00
IUUC-Cne-027005	Cryptococcus neoformans	45.95	5.00e-16	78.60
IUUC-Dno-029834	Dasypus novemcinctus	89.58	6.00e-101	360.00
IUUC-Dor-030315	Dipodomys ordii	88.89	5.00e-108	384.00
IUUC-Ete-032408	Echinops telfairi	88.84	5.00e-93	334.00
IUUC-Eca-034244	Equus caballus	91.45	1.00e-101	361.00
IUUC-Fca-035391	Felis catus	89.50	2.00e-92	331.00
IUUC-Fal-036838	Ficedula albicollis	86.67	1.00e-96	345.00
IUUC-Fox-037925	Fusarium oxysporum	64.71	2.00e-19	89.70
IUUC-Gga-040619	Gallus gallus	87.50	5.00e-97	347.00
IUUC-Gac-041996	Gasterosteus aculeatus	61.16	6.00e-74	270.00
IUUC-Ggo-045481	Gorilla gorilla	86.75	1.00e-93	336.00
IUUC-Hsa-046170	Homo sapiens	86.75	8.00e-94	337.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	91.88	7.00e-101	359.00
IUUC-Lch-050397	Latimeria chalumnae	84.17	3.00e-94	338.00
IUUC-Loc-052038	Lepisosteus oculatus	81.82	8.00e-83	299.00
IUUC-Laf-054126	Loxodonta africana	90.42	4.00e-102	363.00
IUUC-Mcc-055031	Macaca mulatta	86.75	6.00e-94	337.00
IUUC-Meu-056248	Macropus eugenii	90.13	7.00e-97	346.00
IUUC-Mga-059217	Meleagris gallopavo	89.27	3.00e-96	344.00
IUUC-Mmr-061581	Microcebus murinus	91.25	5.00e-103	366.00
IUUC-Mdo-062452	Monodelphis domestica	88.33	1.00e-98	352.00
IUUC-Mmu-063412	Mus musculus	91.25	1.00e-102	365.00
IUUC-Mpu-066479	Mustela putorius furo	91.10	8.00e-102	363.00
IUUC-Mlu-067723	Myotis lucifugus	90.60	4.00e-100	357.00
IUUC-Nle-069122	Nomascus leucogenys	85.83	3.00e-95	341.00
IUUC-Opr-070835	Ochotona princeps	85.84	2.00e-86	311.00
IUUC-Oan-073023	Ornithorhynchus anatinus	85.14	7.00e-96	343.00
IUUC-Ola-086891	Oryzias latipes	62.08	7.00e-75	273.00
IUUC-Oga-087954	Otolemur garnettii	89.58	4.00e-101	360.00
IUUC-Oar-090006	Ovis aries	87.08	1.00e-97	348.00
IUUC-Ptr-090589	Pan troglodytes	85.42	6.00e-95	340.00
IUUC-Pan-091896	Papio anubis	86.75	5.00e-94	337.00
IUUC-Psi-093266	Pelodiscus sinensis	88.33	6.00e-99	353.00
IUUC-Pma-094265	Petromyzon marinus	75.34	3.00e-33	133.00
IUUC-Pab-098253	Pongo abelii	85.00	2.00e-94	338.00
IUUC-Pva-102753	Pteropus vampyrus	87.18	1.00e-88	319.00
IUUC-Rno-105964	Rattus norvegicus	92.31	4.00e-92	330.00
IUUC-Sha-107270	Sarcophilus harrisii	87.50	4.00e-97	347.00
IUUC-Tgu-116822	Taeniopygia guttata	87.08	9.00e-97	346.00
IUUC-Tre-121950	Trichoderma reesei	64.29	3.00e-19	90.50
IUUC-Tvi-122341	Trichoderma virens	62.50	6.00e-16	76.30
IUUC-Ttr-128672	Tursiops truncatus	90.17	1.00e-98	352.00
IUUC-Xtr-132200	Xenopus tropicalis	80.00	6.00e-88	317.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence