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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Spo-108281
Ensembl Protein ID SPBC1711.10c.1:pep
UniProt Accession Q9P780; NPL4_SCHPO
Genbank Protein ID CAB88240.2
Protein Name Nuclear protein localization protein 4
Genbank Nucleotide ID CU329671
Gene Name npl4; SPBC1711.10c
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
SPBC1711.10c SPBC1711.10c.1 SPBC1711.10c.1:pep
Annotation
mRNA Expression
GEO
Protein-protein Interaction
iRefIndexMentha
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/ZnF/NZF 34.78 7.00e-91 332.00 IUUC-Hsa-046334
UBD/ZnF/NZF 34.43 3.00e-90 330.00 IUUC-Mmu-063916
UBD/ZnF/NZF 34.43 2.00e-90 330.00 IUUC-Rno-105582
UBD/ZnF/Other 41.98 6.00e-132 466.00 IUUC-Sce-106145
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Schizosaccharomyces pombe
Functional Description
(View)

Functional Description


     Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity).
 Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity).
Protein Sequence
(Fasta)
MILRFRSKRG MARAEFQPTD TLAMLSAKIL SDILKNDYSP ENVSLCQNES DQGVIFSNLN 60
DQTLQDAGLT HGQMLYLRLG TPNSDIASSN NEPALTVTGA PKQVSTPDVS EKKPSMPVIQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Spo-108281|UBD,NZF;UBD,UBD/ZnF/Other|Schizosaccharomyces pombe
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TATACACTAC GGCGTCTGTT CAATCGTTAT TGTTATTAAC GAATTTTTCA AAAATGTAAC 60
GAAGCTGCAC TTCACCTATT TTAATAGCTT ACATAGTCGT AAGCTTAGTT TGCTCATCCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Spo-108281|UBD,NZF;UBD,UBD/ZnF/Other|Schizosaccharomyces pombe
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0256--Endoplasmic reticulum
KW-0472--Membrane
KW-0509--mRNA transport
KW-0539--Nucleus
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0811--Translocation
KW-0813--Transport
Interpro

IPR016563--Npl4
IPR007717--NPL4_C
IPR024682--Npl4_Ub-like_dom
IPR007716--NPL4_Zn-bd_put
IPR029071--Ubiquitin-rel_dom
Pfam

PF05021--NPL4
PF11543--UN_NPL4
PF05020--zf-NPL4
Gene Ontology

GO:0036266--C:Cdc48p-Npl4p-Vms1p AAA ATPase complex
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0000836--C:Hrd1p ubiquitin ligase complex
GO:0031965--C:nuclear membrane
GO:0042175--C:nuclear outer membrane-endoplasmic reticulum membrane network
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:1990112--C:RQC complex
GO:0043130--F:ubiquitin binding
GO:0031625--F:ubiquitin protein ligase binding
GO:0051028--P:mRNA transport
GO:0015031--P:protein transport
GO:1990116--P:ribosome-associated ubiquitin-dependent protein catabolic process
GO:0030433--P:ubiquitin-dependent ERAD pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG spo:SPBC1711.10c
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000460 Aegilops tauschii 28.09 1.00e-09 55.80
IUUC-Aml-002268 Ailuropoda melanoleuca 34.67 4.00e-91 327.00
IUUC-Atr-002939 Amborella trichopoda 24.73 3.00e-06 44.30
IUUC-Apl-003496 Anas platyrhynchos 35.34 1.00e-89 322.00
IUUC-Aca-005230 Anolis carolinensis 34.62 4.00e-90 323.00
IUUC-Aly-006056 Arabidopsis lyrata 23.53 6.00e-07 46.60
IUUC-Ath-006993 Arabidopsis thaliana 23.86 6.00e-08 50.10
IUUC-Ago-007954 Ashbya gossypii 43.69 4.00e-121 426.00
IUUC-Acl-008208 Aspergillus clavatus 45.20 5.00e-137 479.00
IUUC-Afl-008574 Aspergillus flavus 44.82 2.00e-141 494.00
IUUC-Afu-008825 Aspergillus fumigatus 45.11 9.00e-145 505.00
IUUC-Ani-009495 Aspergillus nidulans 44.00 2.00e-138 484.00
IUUC-Ang-009762 Aspergillus niger 45.36 1.00e-141 494.00
IUUC-Aor-010199 Aspergillus oryzae 44.43 1.00e-140 491.00
IUUC-Ate-010592 Aspergillus terreus 45.84 1.00e-144 504.00
IUUC-Ame-011587 Astyanax mexicanus 33.20 2.00e-32 131.00
IUUC-Bgr-012124 Blumeria graminis 42.72 4.00e-132 462.00
IUUC-Bta-013312 Bos taurus 34.61 5.00e-93 333.00
IUUC-Bci-013648 Botrytis cinerea 41.08 1.00e-136 478.00
IUUC-Bdi-014326 Brachypodium distachyon 25.86 6.00e-10 56.60
IUUC-Bol-016294 Brassica oleracea 25.26 5.00e-07 46.60
IUUC-Bra-017023 Brassica rapa 23.94 1.00e-06 45.80
IUUC-Cel-018713 Caenorhabditis elegans 36.36 6.00e-73 266.00
IUUC-Cja-018869 Callithrix jacchus 34.43 1.00e-91 328.00
IUUC-Cfa-020757 Canis familiaris 34.61 1.00e-91 328.00
IUUC-Cpo-022390 Cavia porcellus 34.32 2.00e-88 317.00
IUUC-Csa-023366 Chlorocebus sabaeus 34.78 5.00e-93 333.00
IUUC-Cho-024455 Choloepus hoffmanni 32.94 5.00e-62 229.00
IUUC-Cin-025638 Ciona intestinalis 34.17 9.00e-65 239.00
IUUC-Csv-026310 Ciona savignyi 31.57 6.00e-63 233.00
IUUC-Cgl-026685 Colletotrichum gloeosporioides 43.64 3.00e-137 480.00
IUUC-Cne-026794 Cryptococcus neoformans 40.71 3.00e-107 380.00
IUUC-Cme-027248 Cyanidioschyzon merolae 29.86 2.00e-07 48.50
IUUC-Dre-027689 Danio rerio 34.77 1.00e-88 318.00
IUUC-Dno-030004 Dasypus novemcinctus 34.78 2.00e-91 328.00
IUUC-Dor-030585 Dipodomys ordii 37.36 3.00e-85 306.00
IUUC-Dse-031202 Dothistroma septosporum 41.89 5.00e-134 469.00
IUUC-Dme-032092 Drosophila melanogaster 35.58 1.00e-89 322.00
IUUC-Ete-033009 Echinops telfairi 40.13 3.00e-31 127.00
IUUC-Eca-034001 Equus caballus 34.61 2.00e-92 331.00
IUUC-Eeu-034485 Erinaceus europaeus 26.89 5.00e-50 190.00
IUUC-Fca-036128 Felis catus 37.45 1.00e-88 318.00
IUUC-Fal-037523 Ficedula albicollis 34.79 8.00e-92 329.00
IUUC-Fox-037802 Fusarium oxysporum 44.07 3.00e-148 516.00
IUUC-Fso-038152 Fusarium solani 44.16 4.00e-148 516.00
IUUC-Gmo-038486 Gadus morhua 41.67 1.00e-83 302.00
IUUC-Ggr-039916 Gaeumannomyces graminis 43.05 2.00e-140 491.00
IUUC-Gga-041208 Gallus gallus 34.44 7.00e-93 332.00
IUUC-Gac-042304 Gasterosteus aculeatus 32.87 3.00e-79 287.00
IUUC-Gma-044178 Glycine max 23.60 3.00e-07 47.80
IUUC-Ggo-045236 Gorilla gorilla 33.62 1.00e-84 305.00
IUUC-Hsa-046334 Homo sapiens 34.78 7.00e-93 332.00
IUUC-Hvu-047323 Hordeum vulgare 23.62 8.00e-04 35.00
IUUC-Itr-047878 Ictidomys tridecemlineatus 38.23 1.00e-70 258.00
IUUC-Lch-050302 Latimeria chalumnae 32.87 7.00e-82 296.00
IUUC-Lpe-051362 Leersia perrieri 24.71 7.00e-10 56.20
IUUC-Loc-052548 Lepisosteus oculatus 34.68 2.00e-88 318.00
IUUC-Lma-053092 Leptosphaeria maculans 43.91 3.00e-140 490.00
IUUC-Laf-053911 Loxodonta africana 34.44 5.00e-92 329.00
IUUC-Mcc-055830 Macaca mulatta 34.84 6.00e-93 332.00
IUUC-Meu-056460 Macropus eugenii 36.36 8.00e-09 53.10
IUUC-Mor-057189 Magnaporthe oryzae 45.63 4.00e-153 533.00
IUUC-Mpo-057366 Magnaporthe poae 43.45 1.00e-144 504.00
IUUC-Mtr-057834 Medicago truncatula 23.03 3.00e-06 44.30
IUUC-Mla-059190 Melampsora laricipopulina 43.98 5.00e-118 416.00
IUUC-Mga-060036 Meleagris gallopavo 34.50 1.00e-92 332.00
IUUC-Mvi-060275 Microbotryum violaceum 43.92 7.00e-118 416.00
IUUC-Mmr-061300 Microcebus murinus 34.32 4.00e-91 326.00
IUUC-Mdo-062911 Monodelphis domestica 35.98 2.00e-92 331.00
IUUC-Mmu-063916 Mus musculus 34.43 2.00e-89 321.00
IUUC-Mac-065601 Musa acuminata 27.91 4.00e-08 50.40
IUUC-Mpu-065912 Mustela putorius furo 34.43 1.00e-90 325.00
IUUC-Mlu-067965 Myotis lucifugus 34.67 1.00e-93 335.00
IUUC-Nfi-068465 Neosartorya fischeri 44.78 9.00e-144 501.00
IUUC-Ncr-068936 Neurospora crassa 44.78 4.00e-146 509.00
IUUC-Nle-069570 Nomascus leucogenys 34.78 4.00e-93 333.00
IUUC-Opr-071097 Ochotona princeps 35.82 4.00e-79 286.00
IUUC-Ont-071430 Oreochromis niloticus 34.02 1.00e-87 315.00
IUUC-Oan-073709 Ornithorhynchus anatinus 33.47 1.00e-64 238.00
IUUC-Ocu-074875 Oryctolagus cuniculus 32.29 1.00e-80 291.00
IUUC-Oba-075214 Oryza barthii 24.57 7.00e-10 56.20
IUUC-Obr-076758 Oryza brachyantha 23.12 7.00e-09 52.40
IUUC-Ogl-077665 Oryza glaberrima 24.57 7.00e-10 56.20
IUUC-Ogu-078899 Oryza glumaepatula 24.57 7.00e-10 56.20
IUUC-Oin-079167 Oryza indica 24.57 7.00e-10 56.20
IUUC-Olo-080451 Oryza longistaminata 24.57 6.00e-10 55.80
IUUC-Ome-081836 Oryza meridionalis 24.57 8.00e-10 56.20
IUUC-Oni-083019 Oryza nivara 24.57 7.00e-10 56.20
IUUC-Opu-083122 Oryza punctata 24.57 6.00e-10 56.60
IUUC-Oru-084900 Oryza rufipogon 24.57 7.00e-10 56.20
IUUC-Osa-086054 Oryza sativa 24.57 7.00e-10 56.20
IUUC-Ola-087077 Oryzias latipes 37.30 1.00e-74 271.00
IUUC-Oga-088049 Otolemur garnettii 35.17 7.00e-74 269.00
IUUC-Oar-089678 Ovis aries 34.43 4.00e-92 330.00
IUUC-Ptr-091380 Pan troglodytes 34.78 6.00e-93 332.00
IUUC-Pan-092821 Papio anubis 34.49 1.00e-90 325.00
IUUC-Psi-093074 Pelodiscus sinensis 34.27 7.00e-91 325.00
IUUC-Pma-094102 Petromyzon marinus 33.11 8.00e-90 322.00
IUUC-Pno-094987 Phaeosphaeria nodorum 43.87 4.00e-142 496.00
IUUC-Ppa-095368 Physcomitrella patens 23.84 8.00e-08 49.30
IUUC-Pfo-097245 Poecilia formosa 35.03 3.00e-88 317.00
IUUC-Pab-098763 Pongo abelii 34.84 7.00e-93 332.00
IUUC-Pop-099355 Populus trichocarpa 22.67 9.00e-07 45.40
IUUC-Ppe-101990 Prunus persica 22.99 3.00e-07 47.80
IUUC-Pva-102308 Pteropus vampyrus 31.25 2.00e-72 264.00
IUUC-Pgr-103553 Puccinia graminis 39.56 9.00e-115 405.00
IUUC-Pte-104100 Pyrenophora teres 43.41 2.00e-139 487.00
IUUC-Pyt-104482 Pyrenophora triticirepentis 42.79 4.00e-140 489.00
IUUC-Rno-105582 Rattus norvegicus 34.43 1.00e-89 322.00
IUUC-Sce-106145 Saccharomyces cerevisiae 42.42 8.00e-128 448.00
IUUC-Sha-106647 Sarcophilus harrisii 35.19 2.00e-93 334.00
IUUC-Sja-107972 Schizosaccharomyces japonicus 56.08 0.00e+00 646.00
IUUC-Ssl-108617 Sclerotinia sclerotiorum 41.24 7.00e-136 475.00
IUUC-Smo-108933 Selaginella moellendorffii 25.79 1.00e-06 45.80
IUUC-Sit-110083 Setaria italica 26.55 7.00e-11 59.70
IUUC-Sly-111645 Solanum lycopersicum 23.12 3.00e-06 44.30
IUUC-Stu-112422 Solanum tuberosum 23.12 2.00e-06 44.70
IUUC-Sbi-113987 Sorghum bicolor 25.29 4.00e-09 53.90
IUUC-Sre-115095 Sporisorium reilianum 39.03 1.00e-120 425.00
IUUC-Ssc-116141 Sus scrofa 36.04 6.00e-88 316.00
IUUC-Tgu-117492 Taeniopygia guttata 37.37 8.00e-87 311.00
IUUC-Tru-118463 Takifugu rubripes 34.26 8.00e-88 315.00
IUUC-Tsy-118993 Tarsius syrichta 30.14 4.00e-67 246.00
IUUC-Tni-119896 Tetraodon nigroviridis 33.80 2.00e-84 304.00
IUUC-Tca-121169 Theobroma cacao 32.05 3.00e-06 44.30
IUUC-Tre-122046 Trichoderma reesei 42.98 1.00e-143 501.00
IUUC-Tvi-122415 Trichoderma virens 43.46 1.00e-144 504.00
IUUC-Tae-125503 Triticum aestivum 27.37 1.00e-09 55.50
IUUC-Tme-127123 Tuber melanosporum 44.61 2.00e-145 507.00
IUUC-Tbe-127629 Tupaia belangeri 33.13 7.00e-43 166.00
IUUC-Ttr-128476 Tursiops truncatus 34.26 7.00e-74 269.00
IUUC-Uma-129492 Ustilago maydis 40.65 5.00e-123 433.00
IUUC-Vda-129702 Verticillium dahliae 42.14 3.00e-129 453.00
IUUC-Vvi-131090 Vitis vinifera 24.06 4.00e-07 47.00
IUUC-Xtr-131786 Xenopus tropicalis 33.80 1.00e-88 318.00
IUUC-Xma-133997 Xiphophorus maculatus 33.73 5.00e-88 316.00
IUUC-Yli-134537 Yarrowia lipolytica 43.75 9.00e-135 471.00
IUUC-Zma-134847 Zea mays 26.14 2.00e-09 55.10
Created Date 25-Jun-2017

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