iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053428

UUCD1 version

UUC-LoA-00603

Ensembl Protein ID

ENSLAFP00000014724.3

UniProt Accession

G3TJ42; G3TJ42_LOXAF

Protein Name

Uncharacterized protein

Gene Name

POC1B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000017550.3	ENSLAFT00000017553.3	ENSLAFP00000014724.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.70e-57	187.0	138	173
UBD/Beta-Prp	2.50e-81	273.5	54	306

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           Ht +v+c +f +d +l+vs+s D+t+k+WD++  ++
   Q: 138  HTHWVRCAKFsPDgRLIVSCSEDKTVKIWDTTNKHC 173
           9**********999****************998777 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           hk+v+t+v+fsp ++lla++srd+t+++w  +++ + ++++ h+a+v++v+fs dg++l+t+seD+ ikvw++     +++l +h++ v
   Q: 54   HKDVVTSVQFSPVGNLLASASRDRTVRLWIPDKKGKSSEFKAHTAPVRSVDFSADGQLLATASEDKSIKVWNMYRQRFLYSLYRHTHWV 142
           899************************************************************************************** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysl 186
           ++ +fsp+g  +vs s+d+t+++wd+ ++ c++  +s   g+ n v ++p+g +++s++ D tv++Wd++++kll++ +  h + v++l
   Q: 143  RCAKFSPDGRLIVSCSEDKTVKIWDTTNKHCVN-NFSDSVGFANFVDFNPNGTCIASAGSDHTVKIWDIRMNKLLQHYQV-HSGGVNCL 229
           *********************************.*********************************************8.******** PP
   S: 187  sfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW..dlrsgdllktlq 261
           s++++g++l+++s dgt+k+ dl +g+ ++tl+ght +v  v fs+ +e+++sg++D ++ +W  + +  ++ + ++
   Q: 230  SYHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFAVSFSKGGELFASGGADAQVLLWrtNFDELNCKSLIK 306
           ***************************************************************99777777776665 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

EDPVLERYFK GHKAAITSVD FSPNCKQLAT ASWDTFLMLW NFKPQARAFR FVGHKDVVTS 60
VQFSPVGNLL ASASRDRTVR LWIPDKKGKS SEFKAHTAPV RSVDFSADGQ LLATASEDKS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGACCCCG TTCTGGAGCG TTATTTTAAA GGCCACAAAG CTGCCATCAC CTCCGTGGAC 60
TTCAGCCCCA ACTGCAAACA ACTTGGTAAG TTTTATTCTC TTTTTTTTTT TTTCCTTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000922--C:spindle pole
GO:0008283--P:cell proliferation
GO:0060271--P:cilium assembly
GO:0001895--P:retina homeostasis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002219	Ailuropoda melanoleuca	89.04	0.00e+00	821.00
IUUC-Apl-004219	Anas platyrhynchos	62.75	2.00e-164	571.00
IUUC-Aca-005197	Anolis carolinensis	59.96	2.00e-172	598.00
IUUC-Ame-011000	Astyanax mexicanus	56.58	7.00e-159	553.00
IUUC-Bta-012706	Bos taurus	89.19	0.00e+00	864.00
IUUC-Cja-019185	Callithrix jacchus	84.47	0.00e+00	800.00
IUUC-Cfa-021274	Canis familiaris	91.54	0.00e+00	881.00
IUUC-Cpo-022351	Cavia porcellus	81.13	0.00e+00	807.00
IUUC-Csa-023032	Chlorocebus sabaeus	84.36	0.00e+00	801.00
IUUC-Cho-024508	Choloepus hoffmanni	83.17	0.00e+00	694.00
IUUC-Cin-025258	Ciona intestinalis	50.20	2.00e-134	471.00
IUUC-Dre-028703	Danio rerio	57.54	3.00e-157	548.00
IUUC-Dno-028915	Dasypus novemcinctus	91.67	0.00e+00	851.00
IUUC-Dor-030306	Dipodomys ordii	75.45	0.00e+00	637.00
IUUC-Dme-032182	Drosophila melanogaster	46.96	7.00e-81	293.00
IUUC-Ete-032353	Echinops telfairi	77.07	0.00e+00	698.00
IUUC-Eca-034136	Equus caballus	90.11	0.00e+00	817.00
IUUC-Eeu-034611	Erinaceus europaeus	78.04	1.00e-176	612.00
IUUC-Fca-036205	Felis catus	88.76	0.00e+00	772.00
IUUC-Fal-036947	Ficedula albicollis	53.81	2.00e-140	492.00
IUUC-Gga-040847	Gallus gallus	61.36	4.00e-164	570.00
IUUC-Ggo-045194	Gorilla gorilla	89.43	0.00e+00	870.00
IUUC-Hsa-047026	Homo sapiens	89.43	0.00e+00	869.00
IUUC-Itr-048943	Ictidomys tridecemlineatus	86.10	0.00e+00	793.00
IUUC-Lch-050067	Latimeria chalumnae	61.73	6.00e-175	607.00
IUUC-Loc-052409	Lepisosteus oculatus	59.31	1.00e-164	572.00
IUUC-Mcc-054772	Macaca mulatta	89.85	0.00e+00	868.00
IUUC-Meu-056496	Macropus eugenii	76.73	1.00e-168	585.00
IUUC-Mga-059276	Meleagris gallopavo	59.54	1.00e-164	572.00
IUUC-Mmr-061525	Microcebus murinus	89.43	0.00e+00	871.00
IUUC-Mdo-062351	Monodelphis domestica	71.63	0.00e+00	731.00
IUUC-Mmu-063834	Mus musculus	81.99	0.00e+00	806.00
IUUC-Mpu-066453	Mustela putorius furo	88.58	0.00e+00	850.00
IUUC-Mlu-067909	Myotis lucifugus	87.50	0.00e+00	799.00
IUUC-Nle-069206	Nomascus leucogenys	89.43	0.00e+00	871.00
IUUC-Opr-070566	Ochotona princeps	75.90	0.00e+00	719.00
IUUC-Oan-073726	Ornithorhynchus anatinus	69.21	2.00e-178	617.00
IUUC-Ocu-074639	Oryctolagus cuniculus	90.70	0.00e+00	876.00
IUUC-Ola-086913	Oryzias latipes	52.85	1.00e-144	506.00
IUUC-Oga-088061	Otolemur garnettii	90.62	0.00e+00	660.00
IUUC-Oar-090228	Ovis aries	84.20	0.00e+00	851.00
IUUC-Ptr-091420	Pan troglodytes	89.64	0.00e+00	872.00
IUUC-Pan-092228	Papio anubis	89.64	0.00e+00	866.00
IUUC-Psi-093309	Pelodiscus sinensis	64.06	4.00e-173	600.00
IUUC-Pma-094425	Petromyzon marinus	56.65	2.00e-152	532.00
IUUC-Ppa-095677	Physcomitrella patens	45.45	2.00e-81	295.00
IUUC-Pab-098109	Pongo abelii	89.64	0.00e+00	872.00
IUUC-Pca-101012	Procavia capensis	72.94	0.00e+00	661.00
IUUC-Pva-102712	Pteropus vampyrus	89.41	0.00e+00	867.00
IUUC-Rno-105260	Rattus norvegicus	81.36	0.00e+00	807.00
IUUC-Smo-108731	Selaginella moellendorffii	40.07	5.00e-71	260.00
IUUC-Sar-113446	Sorex araneus	77.38	0.00e+00	749.00
IUUC-Ssc-115794	Sus scrofa	93.09	0.00e+00	717.00
IUUC-Tgu-116770	Taeniopygia guttata	55.27	2.00e-143	502.00
IUUC-Tru-117968	Takifugu rubripes	55.34	2.00e-146	512.00
IUUC-Tsy-119316	Tarsius syrichta	73.87	0.00e+00	656.00
IUUC-Tni-120713	Tetraodon nigroviridis	48.64	3.00e-129	454.00
IUUC-Tbe-128071	Tupaia belangeri	85.02	0.00e+00	745.00
IUUC-Ttr-129267	Tursiops truncatus	89.01	0.00e+00	865.00
IUUC-Vpa-130823	Vicugna pacos	81.77	2.00e-175	608.00
IUUC-Xtr-131768	Xenopus tropicalis	59.96	2.00e-168	584.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence