iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-118451

Ensembl Protein ID

ENSTRUP00000020658.1

UniProt Accession

H2T7L8; H2T7L8_TAKRU

Protein Name

Uncharacterized protein

Gene Name

grb2b; grb2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000008254.1	ENSTRUT00000020743.1	ENSTRUP00000020658.1
ENSTRUG00000008254.1	ENSTRUT00000020744.1	ENSTRUP00000020659.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.40e-36	123.0	170	226

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
             +vq+l+d+++q+++eL +++G++++v+  ++ d +W+kg    +g+ G+fP n+v+ ++
   Q: 170  PTYVQALFDFDPQEEGELGFRRGEFIQVL--DNSDPNWWKG--GCNGQTGMFPRNYVKPIS 226
           579**************************..9*********..9**************986 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MEAVAKYDFK ATADDELSFK RGDILKVLNE EYDQNWYKAE LRGKDGFIPK NYIEMKAHPW 60
FYGKIPRAKA EEILNKQRRD GAFLIRESES APGDFSLSVK YGNDVQHFKV LRDGAGKYFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGCCG TTGCCAAGTA CGATTTTAAA GCTACTGCTG ATGATGAGCT AAGTTTCAAA 60
CGTGGAGATA TCCTTAAGGT AACTGACAAT TTTATTGTTT TTAAGATACA GCTATTGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001345	Ailuropoda melanoleuca	82.84	3.00e-100	356.00
IUUC-Apl-003322	Anas platyrhynchos	84.73	6.00e-101	359.00
IUUC-Aca-005193	Anolis carolinensis	86.46	2.00e-116	410.00
IUUC-Ago-007965	Ashbya gossypii	56.60	2.00e-14	72.40
IUUC-Ame-010929	Astyanax mexicanus	83.84	4.00e-114	403.00
IUUC-Bta-012932	Bos taurus	84.72	3.00e-115	407.00
IUUC-Cel-018665	Caenorhabditis elegans	55.46	2.00e-70	258.00
IUUC-Cja-019225	Callithrix jacchus	84.72	3.00e-115	407.00
IUUC-Cfa-020887	Canis familiaris	84.72	3.00e-115	407.00
IUUC-Cpo-022488	Cavia porcellus	84.72	3.00e-115	407.00
IUUC-Csa-023326	Chlorocebus sabaeus	84.72	3.00e-115	407.00
IUUC-Cho-024953	Choloepus hoffmanni	69.43	8.00e-87	312.00
IUUC-Cin-025144	Ciona intestinalis	60.99	4.00e-74	270.00
IUUC-Csv-026210	Ciona savignyi	57.40	3.00e-71	261.00
IUUC-Dre-028403	Danio rerio	86.90	3.00e-118	417.00
IUUC-Dno-029187	Dasypus novemcinctus	83.84	2.00e-114	404.00
IUUC-Dor-030763	Dipodomys ordii	84.72	3.00e-115	407.00
IUUC-Dme-031741	Drosophila melanogaster	60.71	9.00e-75	272.00
IUUC-Ete-032354	Echinops telfairi	59.65	1.00e-71	262.00
IUUC-Eca-033222	Equus caballus	84.72	3.00e-115	407.00
IUUC-Eeu-034513	Erinaceus europaeus	91.92	1.00e-49	189.00
IUUC-Fca-036294	Felis catus	84.72	3.00e-115	407.00
IUUC-Fal-037130	Ficedula albicollis	85.59	2.00e-115	407.00
IUUC-Gmo-039546	Gadus morhua	86.46	6.00e-117	412.00
IUUC-Gga-041139	Gallus gallus	86.03	3.00e-116	410.00
IUUC-Gac-041968	Gasterosteus aculeatus	86.46	7.00e-118	416.00
IUUC-Ggo-044562	Gorilla gorilla	84.72	3.00e-115	407.00
IUUC-Hsa-046730	Homo sapiens	84.72	3.00e-115	407.00
IUUC-Itr-049025	Ictidomys tridecemlineatus	84.72	3.00e-115	407.00
IUUC-Lch-050230	Latimeria chalumnae	56.72	1.00e-76	279.00
IUUC-Loc-052723	Lepisosteus oculatus	86.90	3.00e-118	417.00
IUUC-Laf-053774	Loxodonta africana	83.84	2.00e-114	404.00
IUUC-Mcc-054603	Macaca mulatta	84.72	3.00e-115	407.00
IUUC-Meu-056173	Macropus eugenii	70.31	3.00e-91	327.00
IUUC-Mga-059950	Meleagris gallopavo	86.03	3.00e-116	410.00
IUUC-Mmr-060878	Microcebus murinus	84.72	3.00e-115	407.00
IUUC-Mdo-062454	Monodelphis domestica	85.15	2.00e-115	407.00
IUUC-Mmu-063913	Mus musculus	84.72	2.00e-115	407.00
IUUC-Mpu-066125	Mustela putorius furo	84.72	3.00e-115	407.00
IUUC-Mlu-068007	Myotis lucifugus	84.72	3.00e-115	407.00
IUUC-Nle-069101	Nomascus leucogenys	84.72	3.00e-115	407.00
IUUC-Opr-071075	Ochotona princeps	84.72	3.00e-115	407.00
IUUC-Ont-072253	Oreochromis niloticus	84.72	8.00e-115	405.00
IUUC-Oan-073107	Ornithorhynchus anatinus	49.33	2.00e-57	214.00
IUUC-Ocu-074583	Oryctolagus cuniculus	84.72	3.00e-115	407.00
IUUC-Ola-086586	Oryzias latipes	87.57	8.00e-84	303.00
IUUC-Oga-089047	Otolemur garnettii	84.72	3.00e-115	407.00
IUUC-Oar-089904	Ovis aries	78.70	6.00e-105	372.00
IUUC-Ptr-090678	Pan troglodytes	84.72	3.00e-115	407.00
IUUC-Pan-092090	Papio anubis	84.72	3.00e-115	407.00
IUUC-Psi-093765	Pelodiscus sinensis	86.03	2.00e-116	410.00
IUUC-Pma-094650	Petromyzon marinus	78.83	8.00e-104	369.00
IUUC-Pfo-096131	Poecilia formosa	87.34	5.00e-119	419.00
IUUC-Pab-098709	Pongo abelii	84.72	3.00e-115	407.00
IUUC-Pca-100581	Procavia capensis	82.76	2.00e-99	354.00
IUUC-Pva-103066	Pteropus vampyrus	84.72	3.00e-115	407.00
IUUC-Rno-105224	Rattus norvegicus	84.72	3.00e-115	407.00
IUUC-Sce-106302	Saccharomyces cerevisiae	56.60	2.00e-16	79.00
IUUC-Sha-107247	Sarcophilus harrisii	84.24	1.00e-100	358.00
IUUC-Sar-113277	Sorex araneus	72.05	3.00e-93	333.00
IUUC-Ssc-115478	Sus scrofa	84.72	3.00e-115	407.00
IUUC-Tgu-117479	Taeniopygia guttata	85.15	3.00e-115	406.00
IUUC-Tsy-119029	Tarsius syrichta	86.08	6.00e-75	272.00
IUUC-Tbe-128097	Tupaia belangeri	84.28	2.00e-114	404.00
IUUC-Ttr-128871	Tursiops truncatus	91.67	9.00e-83	298.00
IUUC-Vpa-130754	Vicugna pacos	84.72	3.00e-115	407.00
IUUC-Xtr-132275	Xenopus tropicalis	87.34	3.00e-119	420.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence