iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-106732

Ensembl Protein ID

ENSSHAP00000005132.1

UniProt Accession

G3VPM7; G3VPM7_SARHA

Genbank Protein ID

ENSSHAP00000005132

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01176814

Gene Name

OTUD7B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000004490.1	ENSSHAT00000005183.1	ENSSHAP00000005132.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	1.40e-37	129.3	156	337

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqsllgvfddds.lsdalveaLreltseylqkesdffsefieek...........edekefcqklvepe.... 74
           l+l+t+gDGnCLl+A+s +++g++d+d+ l++al++ + + +++++ ++++++++++++k           ++e++++ kl+++e    
   Q: 156  LPLATTGDGNCLLHAASLGMWGFHDRDLmLRKALYSLMEKGVEKEALRRRWRWQQTQQNKesglvyteeewQKEWKELIKLASSEprmh 244
           6899********************************************************************************98887 PP
   S: 75   ...akg.................eeihifaLaqiLsrpiivvdvdsles.........kvggillpllfpeek.lkkpivLlYrsgHYd 133
              + g                 ee+h+f+La++L+rpi+vv++++l++         ++ggi+lpl++p+++ +++p+vL+Y+++H++
   Q: 245  lgtS-GagcggvesseepvyeslEEFHVFVLAHVLKRPIVVVADTMLRDsggeafapiPFGGIYLPLEVPASRcHRSPLVLAYDQAHFS 332
           7541.256789****************************************************************************** PP
   S: 134  aLval 138
           aLv++
   Q: 333  ALVSM 337
           **986 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

GKNWDVSAAL NDFEQLRQVH AGNLPPPFSE GRGGPRPPEK GPPEREPTRP PRPTLHRQDD 60
IIQEKRLSRG ISHASSSIVS LARSHVSSSG GSGGSSEHPL EMPICAFQLP DLTVFTEDFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATGCAACCT AAATCTTGTA AAATGTGCAC ATTGGTGGTT ATTAGCATTC CAAGTAAAGG 60
ACTCTTGCAT GTTCTTCCAA AGCCTTTCCT CTATTTATTT GATACTCAAG TGATCAGTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR002653--Znf_A20

PROSITE

PS50802--OTU
PS51036--ZF_A20

Pfam

PF02338--OTU
PF01754--zf-A20

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0002385--P:mucosal immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032717--P:negative regulation of interleukin-8 production
GO:1900181--P:negative regulation of protein localization to nucleus
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0035871--P:protein K11-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002119	Ailuropoda melanoleuca	82.42	0.00e+00	1155.00
IUUC-Apl-003567	Anas platyrhynchos	67.26	0.00e+00	928.00
IUUC-Bta-013398	Bos taurus	82.85	0.00e+00	1129.00
IUUC-Cel-018468	Caenorhabditis elegans	50.34	8.00e-81	294.00
IUUC-Cja-019965	Callithrix jacchus	81.92	0.00e+00	1122.00
IUUC-Cfa-020191	Canis familiaris	83.70	0.00e+00	1163.00
IUUC-Cpo-022232	Cavia porcellus	82.48	0.00e+00	1137.00
IUUC-Csa-023593	Chlorocebus sabaeus	82.97	0.00e+00	1204.00
IUUC-Cho-024729	Choloepus hoffmanni	71.90	1.00e-132	467.00
IUUC-Dno-029900	Dasypus novemcinctus	81.92	0.00e+00	1115.00
IUUC-Dor-031121	Dipodomys ordii	80.15	9.00e-163	566.00
IUUC-Ete-032473	Echinops telfairi	80.67	0.00e+00	874.00
IUUC-Eca-033946	Equus caballus	86.70	0.00e+00	889.00
IUUC-Eeu-034670	Erinaceus europaeus	81.14	0.00e+00	1111.00
IUUC-Fca-035871	Felis catus	82.60	0.00e+00	1095.00
IUUC-Fso-038203	Fusarium solani	28.87	1.40e-01	32.00
IUUC-Gga-041105	Gallus gallus	67.52	0.00e+00	929.00
IUUC-Gac-041806	Gasterosteus aculeatus	55.82	0.00e+00	746.00
IUUC-Ggo-045472	Gorilla gorilla	82.97	0.00e+00	1164.00
IUUC-Hsa-046473	Homo sapiens	82.73	0.00e+00	1171.00
IUUC-Itr-048841	Ictidomys tridecemlineatus	83.70	0.00e+00	1157.00
IUUC-Lch-050432	Latimeria chalumnae	62.56	0.00e+00	868.00
IUUC-Mcc-055261	Macaca mulatta	82.85	0.00e+00	1207.00
IUUC-Meu-056477	Macropus eugenii	89.18	0.00e+00	986.00
IUUC-Mga-059533	Meleagris gallopavo	66.86	0.00e+00	905.00
IUUC-Mdo-062847	Monodelphis domestica	93.28	0.00e+00	1205.00
IUUC-Mmu-064260	Mus musculus	81.85	0.00e+00	1078.00
IUUC-Mpu-066876	Mustela putorius furo	78.86	0.00e+00	1083.00
IUUC-Mlu-068039	Myotis lucifugus	82.38	0.00e+00	1154.00
IUUC-Nle-069260	Nomascus leucogenys	82.48	0.00e+00	1172.00
IUUC-Opr-070564	Ochotona princeps	87.17	0.00e+00	657.00
IUUC-Ocu-073824	Oryctolagus cuniculus	91.37	0.00e+00	803.00
IUUC-Oga-088124	Otolemur garnettii	82.38	0.00e+00	1127.00
IUUC-Oar-090086	Ovis aries	83.09	0.00e+00	1138.00
IUUC-Ptr-091622	Pan troglodytes	86.35	0.00e+00	931.00
IUUC-Pan-092724	Papio anubis	82.73	0.00e+00	1194.00
IUUC-Psi-093333	Pelodiscus sinensis	65.75	0.00e+00	922.00
IUUC-Pab-098667	Pongo abelii	82.73	0.00e+00	1157.00
IUUC-Pva-102136	Pteropus vampyrus	82.60	0.00e+00	1115.00
IUUC-Rno-105546	Rattus norvegicus	82.00	0.00e+00	1092.00
IUUC-Sar-113562	Sorex araneus	73.11	0.00e+00	921.00
IUUC-Ssc-116191	Sus scrofa	83.21	0.00e+00	1149.00
IUUC-Tgu-116942	Taeniopygia guttata	76.90	0.00e+00	786.00
IUUC-Tsy-119343	Tarsius syrichta	75.30	0.00e+00	1002.00
IUUC-Tbe-127283	Tupaia belangeri	89.57	0.00e+00	709.00
IUUC-Ttr-128692	Tursiops truncatus	79.81	0.00e+00	1069.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence