iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-063033

UUCD1 version

UUC-MoD-00782

Ensembl Protein ID

ENSMODP00000028516.1

UniProt Accession

F7EDI1; F7EDI1_MONDO

Protein Name

Uncharacterized protein

Gene Name

KLHL6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000013426.3	ENSMODT00000030099.2	ENSMODP00000028516.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.80e-19	69.4	61	124
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	8.10e-11	41.0	160	191

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +Dvil+v+ +ef++h++vLaa+S +F+a+f ++l+e+  ++++ ik+v++e ++ ll++ Yt+k+
   Q: 61   TDVILCVDIQEFSCHRAVLAAASNYFRAMFCNDLKEKY-EKKIIIKGVDAETMNILLDYTYTSKA 124
           7***********************************97.***********************987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           +eNc+gilr+Ad++++++Lk++++ +i+++F+
   Q: 160  PENCVGILRLADTHSLDHLKKQVQGYIIQNFT 191
           89*****************************7 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MGDTMEKSIE GPLTSLDEAH SMKRGDIVEI LNGEKVKFDD TELSRILQSG LENLRLENSL 60
TDVILCVDIQ EFSCHRAVLA AASNYFRAMF CNDLKEKYEK KIIIKGVDAE TMNILLDYTY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGTTGATAA GTGGAGGGTT CTGGGCAGGA AATCTGTTTA GACCCTACAG TGTGACCTGG 60
GTGCAACATC AGAGCTCTTT CAGACTCAAG TATTGACGAT GACATGGTGC CTCCTGAAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR029851--KLHL6
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0000976--F:transcription regulatory region sequence-specific DNA binding
GO:0050853--P:B cell receptor signaling pathway
GO:0002467--P:germinal center formation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001509	Ailuropoda melanoleuca	83.44	0.00e+00	1045.00
IUUC-Apl-003490	Anas platyrhynchos	79.51	0.00e+00	1001.00
IUUC-Aca-005136	Anolis carolinensis	77.48	0.00e+00	949.00
IUUC-Ame-010886	Astyanax mexicanus	62.76	0.00e+00	743.00
IUUC-Bta-013473	Bos taurus	82.95	0.00e+00	1010.00
IUUC-Bra-016823	Brassica rapa	32.50	7.00e-13	67.80
IUUC-Cja-018888	Callithrix jacchus	82.79	0.00e+00	1038.00
IUUC-Cpo-021761	Cavia porcellus	76.06	0.00e+00	936.00
IUUC-Csa-023206	Chlorocebus sabaeus	83.12	0.00e+00	1043.00
IUUC-Csv-026076	Ciona savignyi	37.79	4.00e-104	372.00
IUUC-Dre-027948	Danio rerio	67.70	0.00e+00	809.00
IUUC-Dno-030045	Dasypus novemcinctus	83.12	0.00e+00	1037.00
IUUC-Dor-030839	Dipodomys ordii	93.40	0.00e+00	638.00
IUUC-Eca-033608	Equus caballus	82.95	0.00e+00	1015.00
IUUC-Eeu-034640	Erinaceus europaeus	81.49	0.00e+00	1026.00
IUUC-Fca-036065	Felis catus	83.12	0.00e+00	1041.00
IUUC-Fal-036949	Ficedula albicollis	79.20	0.00e+00	977.00
IUUC-Gmo-039661	Gadus morhua	52.67	9.00e-152	530.00
IUUC-Gga-040740	Gallus gallus	79.25	0.00e+00	996.00
IUUC-Gac-042413	Gasterosteus aculeatus	55.65	0.00e+00	681.00
IUUC-Ggo-045167	Gorilla gorilla	82.95	0.00e+00	1040.00
IUUC-Hsa-046120	Homo sapiens	82.95	0.00e+00	1040.00
IUUC-Itr-047926	Ictidomys tridecemlineatus	83.44	0.00e+00	1044.00
IUUC-Lch-049709	Latimeria chalumnae	73.43	0.00e+00	932.00
IUUC-Loc-052239	Lepisosteus oculatus	71.68	0.00e+00	870.00
IUUC-Laf-054511	Loxodonta africana	82.50	0.00e+00	1032.00
IUUC-Mcc-055109	Macaca mulatta	83.12	0.00e+00	1042.00
IUUC-Meu-056522	Macropus eugenii	77.31	3.00e-106	379.00
IUUC-Mga-060012	Meleagris gallopavo	77.67	0.00e+00	968.00
IUUC-Mmr-061364	Microcebus murinus	82.63	0.00e+00	1035.00
IUUC-Mmu-063880	Mus musculus	81.33	0.00e+00	1000.00
IUUC-Mlu-068233	Myotis lucifugus	82.63	0.00e+00	1027.00
IUUC-Opr-070638	Ochotona princeps	79.10	0.00e+00	706.00
IUUC-Ont-071960	Oreochromis niloticus	54.72	0.00e+00	676.00
IUUC-Oan-073406	Ornithorhynchus anatinus	76.62	0.00e+00	954.00
IUUC-Ocu-074612	Oryctolagus cuniculus	82.41	0.00e+00	1033.00
IUUC-Ola-087181	Oryzias latipes	53.51	0.00e+00	664.00
IUUC-Oga-088955	Otolemur garnettii	82.79	0.00e+00	1035.00
IUUC-Oar-089682	Ovis aries	82.79	0.00e+00	1010.00
IUUC-Ptr-090969	Pan troglodytes	82.95	0.00e+00	1040.00
IUUC-Pan-092289	Papio anubis	83.12	0.00e+00	1043.00
IUUC-Psi-093279	Pelodiscus sinensis	80.16	0.00e+00	1006.00
IUUC-Pab-097957	Pongo abelii	82.68	0.00e+00	773.00
IUUC-Pca-100619	Procavia capensis	80.36	0.00e+00	1016.00
IUUC-Pva-102533	Pteropus vampyrus	76.66	2.00e-159	556.00
IUUC-Pyt-104515	Pyrenophora triticirepentis	36.62	2.00e-07	49.30
IUUC-Rno-106111	Rattus norvegicus	81.98	0.00e+00	1031.00
IUUC-Sha-106716	Sarcophilus harrisii	82.47	0.00e+00	1033.00
IUUC-Tgu-116839	Taeniopygia guttata	79.19	0.00e+00	993.00
IUUC-Tru-117792	Takifugu rubripes	53.95	0.00e+00	659.00
IUUC-Tsy-119609	Tarsius syrichta	72.86	7.00e-110	390.00
IUUC-Tni-119682	Tetraodon nigroviridis	53.46	0.00e+00	658.00
IUUC-Tme-127039	Tuber melanosporum	31.85	2.00e-13	71.60
IUUC-Tbe-127961	Tupaia belangeri	76.95	0.00e+00	926.00
IUUC-Ttr-128917	Tursiops truncatus	81.01	0.00e+00	839.00
IUUC-Vpa-130721	Vicugna pacos	82.05	0.00e+00	704.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence