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Tag Content
UUCD2 ID IUUC-Ssc-115600
UUCD1 version UUC-SuS-00112
Ensembl Protein ID ENSSSCP00000008227.2
UniProt Accession Q865W2; TRI50_PIG
Genbank Protein ID AAL91074.1
Protein Name E3 ubiquitin-protein ligase TRIM50; RING-type E3 ubiquitin transferase TRIM50; Tripartite motif-containing protein 50
Genbank Nucleotide ID AY081951
Gene Name TRIM50
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSSCG00000007703.2 ENSSSCT00000008446.2 ENSSSCP00000008227.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 3.70e-08 34.0 16 57
E3 activity/RING/U-box 9.90e-09 35.4 12 77
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle fk+ pl l+CgH +++ Cl  +   ++    e rCP+Cr
   Q: 16   CPVCLEVFKE-PLMLQCGHSYCKGCLLSL---SRHLDSELRCPVCR 57
           ********99.999************555...778**********8 PP
   

   E3 activity/RING/U-box
   S: 4    eeflCpIslelMrdPvvlpsGitydrss...IekwlasggktcPvtrqplteedlvPnltlrrliqa 67
           + + Cp+ le++++P +l++G++y + +   + ++l+s  + cPv+rq++++++  Pn +l r+i+a
   Q: 12   DRLQCPVCLEVFKEPLMLQCGHSYCKGCllsLSRHLDSELR-CPVCRQEVDSSSSPPNVSLARVIEA 77
           5689*********************9862226899999999.**********************986 PP
   
Organism Sus scrofa
Functional Description
(View)

Functional Description


     E3 ubiquitin-protein ligase.
 E3 ubiquitin-protein ligase.
Protein Sequence
(Fasta)
MAWQVSVPEL EDRLQCPVCL EVFKEPLMLQ CGHSYCKGCL LSLSRHLDSE LRCPVCRQEV 60
DSSSSPPNVS LARVIEALQL PGDPEPQVCT HHRNPLSLFC EKDQELICGL CGLLGSHQHH 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ssc-115600|E3,RING;E3,U-box|Sus scrofa
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGCGTGGC AGGTGAGTGT GCCCGAGCTG GAGGACCGCC TGCAGTGCCC CGTCTGCCTC 60
GAGGTCTTCA AGGAGCCCCT GATGCTGCAG TGCGGCCACT CCTACTGCAA GGGCTGCCTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ssc-115600|E3,RING;E3,U-box|Sus scrofa
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0832--Ubl conjugation
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box
PF13445--zf-RING_UBOX
PRINTS

PR01407--BUTYPHLNCDUF
SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY
Gene Ontology

GO:0016235--C:aggresome
GO:0005737--C:cytoplasm
GO:0016740--F:transferase activity
GO:0008270--F:zinc ion binding
GO:0070201--P:regulation of establishment of protein localization
KEGG ssc:397383
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001406 Ailuropoda melanoleuca 92.20 0.00e+00 925.00
IUUC-Apl-004051 Anas platyrhynchos 62.72 2.00e-176 611.00
IUUC-Ame-010964 Astyanax mexicanus 53.56 1.00e-156 546.00
IUUC-Bta-012642 Bos taurus 93.82 0.00e+00 908.00
IUUC-Cel-018397 Caenorhabditis elegans 38.67 5.00e-09 55.80
IUUC-Cja-019011 Callithrix jacchus 88.20 0.00e+00 821.00
IUUC-Cfa-020270 Canis familiaris 90.97 0.00e+00 919.00
IUUC-Cpo-022458 Cavia porcellus 88.89 0.00e+00 858.00
IUUC-Csa-023478 Chlorocebus sabaeus 90.57 0.00e+00 886.00
IUUC-Cne-027043 Cryptococcus neoformans 50.00 2.00e-06 47.00
IUUC-Dno-028894 Dasypus novemcinctus 89.68 0.00e+00 858.00
IUUC-Dor-030228 Dipodomys ordii 84.30 0.00e+00 726.00
IUUC-Eca-033497 Equus caballus 92.61 0.00e+00 926.00
IUUC-Eeu-034910 Erinaceus europaeus 75.67 4.00e-130 457.00
IUUC-Fca-036164 Felis catus 92.61 0.00e+00 933.00
IUUC-Gga-040573 Gallus gallus 56.46 2.00e-96 346.00
IUUC-Ggo-044471 Gorilla gorilla 91.17 0.00e+00 889.00
IUUC-Hsa-046039 Homo sapiens 91.17 0.00e+00 891.00
IUUC-Itr-048897 Ictidomys tridecemlineatus 90.24 0.00e+00 850.00
IUUC-Kpa-049137 Komagataella pastoris 39.73 7.00e-09 55.10
IUUC-Lch-050638 Latimeria chalumnae 56.47 1.00e-162 565.00
IUUC-Loc-051971 Lepisosteus oculatus 55.32 3.00e-156 544.00
IUUC-Laf-054291 Loxodonta africana 89.98 0.00e+00 863.00
IUUC-Mcc-055708 Macaca mulatta 90.57 0.00e+00 885.00
IUUC-Meu-056670 Macropus eugenii 72.91 4.00e-143 500.00
IUUC-Mla-059039 Melampsora laricipopulina 43.08 1.00e-09 57.00
IUUC-Mga-059415 Meleagris gallopavo 61.64 5.00e-177 613.00
IUUC-Mmr-061410 Microcebus murinus 89.89 0.00e+00 841.00
IUUC-Mmu-064094 Mus musculus 88.20 0.00e+00 880.00
IUUC-Mac-064869 Musa acuminata 36.36 3.00e-09 53.10
IUUC-Mpu-065781 Mustela putorius furo 90.97 0.00e+00 909.00
IUUC-Mlu-067974 Myotis lucifugus 90.64 0.00e+00 873.00
IUUC-Nle-069000 Nomascus leucogenys 90.76 0.00e+00 888.00
IUUC-Opr-071216 Ochotona princeps 90.23 5.00e-115 407.00
IUUC-Ocu-074859 Oryctolagus cuniculus 90.54 0.00e+00 864.00
IUUC-Oga-088285 Otolemur garnettii 88.09 0.00e+00 882.00
IUUC-Oar-090161 Ovis aries 84.22 0.00e+00 807.00
IUUC-Ptr-091672 Pan troglodytes 91.17 0.00e+00 892.00
IUUC-Pan-092870 Papio anubis 90.98 0.00e+00 889.00
IUUC-Psi-093742 Pelodiscus sinensis 64.92 0.00e+00 651.00
IUUC-Pab-098034 Pongo abelii 91.58 0.00e+00 895.00
IUUC-Pca-100115 Procavia capensis 79.88 3.00e-68 251.00
IUUC-Pva-103234 Pteropus vampyrus 91.90 0.00e+00 886.00
IUUC-Rno-105163 Rattus norvegicus 87.78 0.00e+00 858.00
IUUC-Sha-106575 Sarcophilus harrisii 66.74 4.00e-167 580.00
IUUC-Sja-107830 Schizosaccharomyces japonicus 37.88 5.00e-07 48.90
IUUC-Tbe-128151 Tupaia belangeri 91.26 1.00e-97 348.00
IUUC-Ttr-128947 Tursiops truncatus 93.22 0.00e+00 894.00
Created Date 25-Jun-2017

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