iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-065973

Ensembl Protein ID

ENSMPUP00000004984.1

UniProt Accession

M3Y0Y3; M3Y0Y3_MUSPF

Genbank Protein ID

ENSMPUP00000004984

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01052125

Gene Name

RNF144B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000005023.1	ENSMPUT00000005069.1	ENSMPUP00000004984.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	4.10e-52	177.6	63	255

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpek..leeseikellveeelykryekllleevveadaal 88
           Ck+Cl+e+s +++t+l eC++ fC++Clkqyl+l+i+eg+ + i cp++ c ++  l+e+ei++ lv  ++++ y++l++e++v+ d+++
   Q: 63   CKLCLCEQSLDKMTTLRECRCLFCTACLKQYLQLAIREGCGSPIACPDTVCLNHgtLQEAEIAS-LVPVDQFQLYQRLKFEREVHLDPHR 151
           ***************************************************9988899******.6999********************* PP
   S: 89   kwcpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyiekneg 176
           +wcp +dC++v+ +++ +  + ++vec++c+ +fC++Ck++wH+++sC++ +  +  te   ++a   + +ea +k+Cp C+vyie+neg
   Q: 152  TWCPVADCQTVCPVASGDpgQPVQVECPSCHLKFCSCCKDAWHAEVSCRDSQPIVLPTE---HRALFGTDAEAPIKQCPVCRVYIERNEG 238
           **************998877899999*****************************9999...99************************** PP
   S: 177  CnhmtCakCkaefCwlC 193
           C++m+C++Ck++fCw+C
   Q: 239  CAQMMCKNCKHTFCWYC 255
           ***************** PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MRGGRMERSL EMSGRQEHLV KGLRSLETGE ERLMGSGGRT QYLTMTTENP AAGELAPAPL 60
VTCKLCLCEQ SLDKMTTLRE CRCLFCTACL KQYLQLAIRE GCGSPIACPD TVCLNHGTLQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATTGTAGCC ATGCAACTCC TAAACGGGAT GTGTGTTCCT TGTGGTCTTC TCATCCTGTA 60
ATTTACATGA GAGGAGGCAG GATGGAGAGG TCCCTGGAAA TGTCAGGACG CCAGGAACAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0031966--C:mitochondrial membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001257	Ailuropoda melanoleuca	96.04	6.00e-174	602.00
IUUC-Apl-004112	Anas platyrhynchos	79.00	5.00e-127	447.00
IUUC-Aca-004533	Anolis carolinensis	74.60	1.00e-137	482.00
IUUC-Bta-012641	Bos taurus	90.79	7.00e-163	566.00
IUUC-Cja-019626	Callithrix jacchus	77.56	2.00e-137	481.00
IUUC-Cfa-020702	Canis familiaris	95.05	3.00e-172	597.00
IUUC-Cpo-022147	Cavia porcellus	91.75	8.00e-165	572.00
IUUC-Csa-023473	Chlorocebus sabaeus	93.40	3.00e-171	593.00
IUUC-Cho-024298	Choloepus hoffmanni	87.16	2.00e-134	471.00
IUUC-Dre-028099	Danio rerio	65.04	4.00e-91	327.00
IUUC-Dno-029122	Dasypus novemcinctus	82.28	2.00e-152	531.00
IUUC-Dor-030669	Dipodomys ordii	94.42	1.00e-131	461.00
IUUC-Ete-033141	Echinops telfairi	77.89	3.00e-127	447.00
IUUC-Eca-034360	Equus caballus	93.07	7.00e-169	585.00
IUUC-Eeu-034538	Erinaceus europaeus	72.77	4.00e-84	303.00
IUUC-Fca-036055	Felis catus	92.74	4.00e-167	580.00
IUUC-Fal-037339	Ficedula albicollis	78.49	4.00e-130	457.00
IUUC-Gmo-038780	Gadus morhua	61.17	9.00e-86	310.00
IUUC-Gga-040256	Gallus gallus	77.58	3.00e-130	457.00
IUUC-Gac-042127	Gasterosteus aculeatus	59.09	6.00e-93	333.00
IUUC-Ggo-044867	Gorilla gorilla	94.06	6.00e-172	595.00
IUUC-Hsa-046928	Homo sapiens	93.73	3.00e-171	593.00
IUUC-Hvu-047484	Hordeum vulgare	30.73	3.00e-17	83.20
IUUC-Itr-048250	Ictidomys tridecemlineatus	97.41	5.00e-111	392.00
IUUC-Lch-050168	Latimeria chalumnae	73.77	3.00e-132	464.00
IUUC-Lpe-051649	Leersia perrieri	28.71	4.00e-17	83.60
IUUC-Loc-052150	Lepisosteus oculatus	59.50	4.00e-85	307.00
IUUC-Laf-053967	Loxodonta africana	91.42	5.00e-165	573.00
IUUC-Mcc-055898	Macaca mulatta	93.40	3.00e-171	593.00
IUUC-Meu-056628	Macropus eugenii	97.44	1.00e-43	169.00
IUUC-Mtr-058227	Medicago truncatula	28.11	4.00e-19	88.60
IUUC-Mga-059820	Meleagris gallopavo	76.87	2.00e-129	455.00
IUUC-Mmr-060680	Microcebus murinus	92.41	6.00e-167	579.00
IUUC-Mdo-062839	Monodelphis domestica	84.21	1.00e-151	528.00
IUUC-Mmu-063339	Mus musculus	85.48	3.00e-145	507.00
IUUC-Mac-065414	Musa acuminata	28.91	1.00e-19	90.10
IUUC-Mlu-067112	Myotis lucifugus	91.42	5.00e-157	546.00
IUUC-Nle-069795	Nomascus leucogenys	92.06	1.00e-175	608.00
IUUC-Opr-070390	Ochotona princeps	85.15	1.00e-148	518.00
IUUC-Ont-072329	Oreochromis niloticus	59.09	3.00e-89	321.00
IUUC-Oan-072980	Ornithorhynchus anatinus	79.22	1.00e-138	485.00
IUUC-Ocu-073845	Oryctolagus cuniculus	92.41	5.00e-167	579.00
IUUC-Ola-086872	Oryzias latipes	59.01	6.00e-85	306.00
IUUC-Oga-088954	Otolemur garnettii	92.74	3.00e-168	583.00
IUUC-Oar-089879	Ovis aries	91.45	8.00e-164	569.00
IUUC-Ptr-090685	Pan troglodytes	93.73	3.00e-171	593.00
IUUC-Pan-092086	Papio anubis	93.07	4.00e-171	593.00
IUUC-Psi-093481	Pelodiscus sinensis	79.87	7.00e-136	476.00
IUUC-Pfo-096065	Poecilia formosa	64.77	7.00e-92	330.00
IUUC-Pab-098031	Pongo abelii	93.07	5.00e-170	589.00
IUUC-Pca-100936	Procavia capensis	89.44	6.00e-161	559.00
IUUC-Pva-102864	Pteropus vampyrus	82.18	3.00e-144	504.00
IUUC-Rno-105503	Rattus norvegicus	85.81	5.00e-146	509.00
IUUC-Sha-107425	Sarcophilus harrisii	84.87	7.00e-153	532.00
IUUC-Stu-112736	Solanum tuberosum	27.98	4.00e-20	91.70
IUUC-Ssc-115458	Sus scrofa	90.23	1.00e-152	532.00
IUUC-Tgu-117226	Taeniopygia guttata	77.78	6.00e-130	456.00
IUUC-Tru-118362	Takifugu rubripes	64.29	2.00e-93	335.00
IUUC-Tsy-119255	Tarsius syrichta	92.41	4.00e-167	580.00
IUUC-Tni-120140	Tetraodon nigroviridis	60.65	9.00e-87	312.00
IUUC-Tae-124420	Triticum aestivum	31.82	2.00e-18	87.00
IUUC-Tbe-127306	Tupaia belangeri	91.09	3.00e-164	570.00
IUUC-Ttr-128923	Tursiops truncatus	90.79	2.00e-151	527.00
IUUC-Vpa-130148	Vicugna pacos	91.42	5.00e-164	569.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence