iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-005339

Ensembl Protein ID

ENSACAP00000005495.2

UniProt Accession

G1KEE5; G1KEE5_ANOCA

Protein Name

Histone-lysine N-methyltransferase

Gene Name

NSD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000005566.2	ENSACAT00000005615.2	ENSACAP00000005495.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	5.00e-17	61.8	1243	1283

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C vC egg+    l++Ce C  +fH +Cl++     +p+ + w+C++C+
   Q: 1243 WCFVCSEGGS----LLCCESCPAAFHRECLNID----MPEGS-WYCNDCK 1283
           8*********....*******************....99998.******8 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

LPKVPKRFMA KWEISVGLTS EYLKQNGTQK CIQTSSKMDS EKETRLMGSH EKVSLNEQNM 60
QLNGCLKSFA LDSKHFAHDK EKIVTKSRTK KSSDTRKRNR VRKSSTKLET SKKEYGEKVP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTACCTAAGG TTCCCAAGAG GTTTATGGCT AAGTGGGAGA TCAGTGTTGG TCTTACAAGT 60
GAATATCTTA AACAGAATGG TACCCAGAAA TGCATCCAGA CTTCTAGCAA AATGGACAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR006560--AWS_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51215--AWS
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00855--PWWP
PF00856--SET

SMART

SM00570--AWS
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000229	Aegilops tauschii	54.17	4.00e-04	41.20
IUUC-Aml-001795	Ailuropoda melanoleuca	58.68	0.00e+00	1514.00
IUUC-Apl-003953	Anas platyrhynchos	54.83	0.00e+00	1924.00
IUUC-Bta-012966	Bos taurus	50.63	0.00e+00	1807.00
IUUC-Cja-018780	Callithrix jacchus	51.22	0.00e+00	1796.00
IUUC-Cfa-020975	Canis familiaris	58.56	0.00e+00	1501.00
IUUC-Cpo-021331	Cavia porcellus	58.59	0.00e+00	1494.00
IUUC-Csa-024226	Chlorocebus sabaeus	50.47	0.00e+00	1768.00
IUUC-Cho-024464	Choloepus hoffmanni	70.44	2.00e-120	427.00
IUUC-Csv-026298	Ciona savignyi	38.54	2.00e-57	216.00
IUUC-Dre-027488	Danio rerio	75.78	0.00e+00	1236.00
IUUC-Dno-029230	Dasypus novemcinctus	49.86	0.00e+00	1701.00
IUUC-Dor-031016	Dipodomys ordii	68.69	0.00e+00	1053.00
IUUC-Dme-032193	Drosophila melanogaster	35.78	9.00e-121	428.00
IUUC-Eca-033591	Equus caballus	50.61	0.00e+00	1798.00
IUUC-Fca-035791	Felis catus	59.11	0.00e+00	1521.00
IUUC-Fal-037378	Ficedula albicollis	55.72	0.00e+00	1868.00
IUUC-Gmo-038919	Gadus morhua	71.29	0.00e+00	946.00
IUUC-Gga-040881	Gallus gallus	55.64	0.00e+00	1923.00
IUUC-Gac-041378	Gasterosteus aculeatus	77.94	0.00e+00	1057.00
IUUC-Hsa-046436	Homo sapiens	51.01	0.00e+00	1791.00
IUUC-Hvu-047760	Hordeum vulgare	39.66	6.00e-09	57.40
IUUC-Itr-048194	Ictidomys tridecemlineatus	51.05	0.00e+00	1798.00
IUUC-Lch-049684	Latimeria chalumnae	81.04	0.00e+00	1260.00
IUUC-Laf-054046	Loxodonta africana	51.43	0.00e+00	1801.00
IUUC-Mcc-055593	Macaca mulatta	50.42	0.00e+00	1769.00
IUUC-Mga-059756	Meleagris gallopavo	54.77	0.00e+00	1961.00
IUUC-Mmr-061182	Microcebus murinus	51.87	0.00e+00	1837.00
IUUC-Mdo-061984	Monodelphis domestica	57.97	0.00e+00	1461.00
IUUC-Mmu-063605	Mus musculus	52.56	0.00e+00	1872.00
IUUC-Mpu-066446	Mustela putorius furo	50.09	0.00e+00	1772.00
IUUC-Mlu-067261	Myotis lucifugus	57.90	0.00e+00	1503.00
IUUC-Nle-069818	Nomascus leucogenys	50.89	0.00e+00	1788.00
IUUC-Opr-070842	Ochotona princeps	65.87	0.00e+00	1296.00
IUUC-Ont-072448	Oreochromis niloticus	74.55	0.00e+00	1138.00
IUUC-Oan-073496	Ornithorhynchus anatinus	75.54	0.00e+00	1488.00
IUUC-Ocu-074918	Oryctolagus cuniculus	50.02	0.00e+00	1803.00
IUUC-Obr-076753	Oryza brachyantha	54.84	1.00e-07	52.40
IUUC-Ola-087518	Oryzias latipes	75.48	0.00e+00	1049.00
IUUC-Oga-088743	Otolemur garnettii	60.17	0.00e+00	1538.00
IUUC-Oar-090265	Ovis aries	50.72	0.00e+00	1809.00
IUUC-Ptr-090521	Pan troglodytes	51.06	0.00e+00	1790.00
IUUC-Psi-093245	Pelodiscus sinensis	57.15	0.00e+00	1769.00
IUUC-Pfo-096066	Poecilia formosa	75.14	0.00e+00	1189.00
IUUC-Pab-098644	Pongo abelii	50.75	0.00e+00	1770.00
IUUC-Pva-103094	Pteropus vampyrus	66.36	0.00e+00	1162.00
IUUC-Rno-105803	Rattus norvegicus	60.97	0.00e+00	1570.00
IUUC-Sha-107278	Sarcophilus harrisii	58.99	0.00e+00	1510.00
IUUC-Sar-113402	Sorex araneus	86.11	0.00e+00	1055.00
IUUC-Sbi-114400	Sorghum bicolor	36.54	8.00e-13	65.50
IUUC-Ssc-116193	Sus scrofa	58.86	0.00e+00	1511.00
IUUC-Tgu-116532	Taeniopygia guttata	92.15	0.00e+00	1270.00
IUUC-Tru-117988	Takifugu rubripes	77.54	0.00e+00	1187.00
IUUC-Tsy-118830	Tarsius syrichta	51.16	0.00e+00	1736.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence