iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036862

Ensembl Protein ID

ENSFALP00000001980.1

UniProt Accession

U3JGS6; U3JGS6_FICAL

Genbank Protein ID

ENSFALP00000001980

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01021238

Gene Name

OPTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000001906.1	ENSFALT00000001992.1	ENSFALP00000001980.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	1.90e-22	78.6	433	492

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklndslkas 60
           +ee+let+ vL++Q+e+Y++DF+aERa+RE+++eeke+L+ q++ l+k+ + l+d ++ s
   Q: 433  QEEDLETMSVLRAQMEVYCSDFHAERAAREKIHEEKEQLAVQLAYLLKEQQNLEDLGRTS 492
           79***************************************************9988765 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MSGKLKGRPA ENEEHSKSKM ENGLDSTAVP ALNTYTPEEM VQQMKELITE NNELKEAMKL 60
HNQAMKDRYE ELSTWREKQK EEREFYELKF KEAKQCLQAK CIENEQLQQQ LQSLKEREEG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCACCGCT CTCTACAAGT CCCTGACAGG ACGGTCAGGT GGATCAGGAT CTGCTCCCTG 60
GAAATCAGCA ACAGGATGAG AGGACATCGC CTCAAGCTGT TCCAGGGAAG CTTTAGGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR021063--NEMO_N
IPR032939--Optineurin
IPR034735--ZF_CCHC_NOA

PROSITE

PS51801--ZF_CCHC_NOA

Pfam

PF16516--CC2-LZ
PF11577--NEMO

Gene Ontology

GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0048471--C:perinuclear region of cytoplasm
GO:0005802--C:trans-Golgi network
GO:0050829--P:defense response to Gram-negative bacterium
GO:0090161--P:Golgi ribbon formation
GO:0043001--P:Golgi to plasma membrane protein transport
GO:0016236--P:macroautophagy
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0001920--P:negative regulation of receptor recycling
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:1904417--P:positive regulation of xenophagy
GO:0000042--P:protein targeting to Golgi

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002037	Ailuropoda melanoleuca	57.09	7.00e-141	493.00
IUUC-Apl-003812	Anas platyrhynchos	83.33	0.00e+00	880.00
IUUC-Aca-004625	Anolis carolinensis	62.28	5.00e-178	617.00
IUUC-Aly-005781	Arabidopsis lyrata	50.00	7.70e-02	31.60
IUUC-Ame-011116	Astyanax mexicanus	37.24	3.00e-63	235.00
IUUC-Bta-013240	Bos taurus	58.05	3.00e-159	555.00
IUUC-Cja-019911	Callithrix jacchus	60.25	7.00e-157	546.00
IUUC-Cfa-020330	Canis familiaris	58.66	4.00e-147	514.00
IUUC-Cpo-021753	Cavia porcellus	56.33	1.00e-147	516.00
IUUC-Csa-023662	Chlorocebus sabaeus	60.07	3.00e-155	541.00
IUUC-Cho-024574	Choloepus hoffmanni	48.40	1.00e-74	272.00
IUUC-Dre-027720	Danio rerio	42.83	6.00e-92	331.00
IUUC-Dno-029079	Dasypus novemcinctus	57.02	6.00e-139	487.00
IUUC-Dor-030890	Dipodomys ordii	56.47	1.00e-153	536.00
IUUC-Dme-032072	Drosophila melanogaster	30.37	3.00e-06	46.20
IUUC-Ete-032568	Echinops telfairi	58.13	3.00e-142	498.00
IUUC-Eca-033528	Equus caballus	58.30	2.00e-151	528.00
IUUC-Eeu-035219	Erinaceus europaeus	55.42	8.00e-143	500.00
IUUC-Fca-035852	Felis catus	56.89	1.00e-146	513.00
IUUC-Fso-038171	Fusarium solani	50.00	2.80e+00	25.80
IUUC-Gmo-038735	Gadus morhua	40.64	3.00e-75	275.00
IUUC-Gga-040939	Gallus gallus	87.25	0.00e+00	901.00
IUUC-Gac-041580	Gasterosteus aculeatus	43.93	4.00e-95	342.00
IUUC-Ggo-045034	Gorilla gorilla	53.29	8.00e-140	490.00
IUUC-Hsa-046624	Homo sapiens	60.14	1.00e-161	562.00
IUUC-Itr-048288	Ictidomys tridecemlineatus	53.57	2.00e-139	489.00
IUUC-Lch-049720	Latimeria chalumnae	50.00	1.00e-78	286.00
IUUC-Loc-052185	Lepisosteus oculatus	45.79	7.00e-107	380.00
IUUC-Laf-054079	Loxodonta africana	57.22	1.00e-145	509.00
IUUC-Mcc-055674	Macaca mulatta	60.62	9.00e-155	540.00
IUUC-Meu-056769	Macropus eugenii	70.12	2.00e-62	233.00
IUUC-Mga-060203	Meleagris gallopavo	86.40	0.00e+00	843.00
IUUC-Mmr-061492	Microcebus murinus	59.75	3.00e-148	518.00
IUUC-Mdo-063051	Monodelphis domestica	58.73	1.00e-166	579.00
IUUC-Mmu-063409	Mus musculus	55.77	2.00e-155	541.00
IUUC-Mpu-065907	Mustela putorius furo	54.23	5.00e-145	507.00
IUUC-Mlu-066957	Myotis lucifugus	58.96	2.00e-146	512.00
IUUC-Nle-069973	Nomascus leucogenys	59.89	6.00e-156	543.00
IUUC-Opr-071049	Ochotona princeps	54.95	6.00e-132	464.00
IUUC-Ont-071915	Oreochromis niloticus	44.34	4.00e-97	348.00
IUUC-Oan-072965	Ornithorhynchus anatinus	57.47	1.00e-158	553.00
IUUC-Ocu-074029	Oryctolagus cuniculus	55.39	1.00e-126	446.00
IUUC-Ola-087019	Oryzias latipes	41.98	5.00e-87	314.00
IUUC-Oga-088613	Otolemur garnettii	59.39	3.00e-155	541.00
IUUC-Oar-090386	Ovis aries	58.23	2.00e-158	552.00
IUUC-Ptr-091619	Pan troglodytes	59.79	9.00e-160	556.00
IUUC-Pan-092178	Papio anubis	58.71	1.00e-154	539.00
IUUC-Psi-093214	Pelodiscus sinensis	68.31	0.00e+00	660.00
IUUC-Pfo-096901	Poecilia formosa	43.06	4.00e-90	325.00
IUUC-Pab-097560	Pongo abelii	64.59	2.00e-115	409.00
IUUC-Pca-100853	Procavia capensis	51.13	3.00e-62	232.00
IUUC-Pva-102255	Pteropus vampyrus	56.60	8.00e-135	473.00
IUUC-Rno-105812	Rattus norvegicus	55.48	7.00e-156	543.00
IUUC-Sha-107225	Sarcophilus harrisii	63.96	7.00e-121	426.00
IUUC-Sar-113736	Sorex araneus	56.91	5.00e-89	321.00
IUUC-Ssc-115422	Sus scrofa	57.94	6.00e-154	537.00
IUUC-Tgu-116924	Taeniopygia guttata	86.08	0.00e+00	835.00
IUUC-Tru-117695	Takifugu rubripes	42.67	8.00e-88	317.00
IUUC-Tsy-119090	Tarsius syrichta	54.06	5.00e-80	291.00
IUUC-Tni-120645	Tetraodon nigroviridis	42.05	2.00e-88	319.00
IUUC-Tbe-127970	Tupaia belangeri	67.96	8.00e-95	340.00
IUUC-Ttr-129244	Tursiops truncatus	58.65	2.00e-150	525.00
IUUC-Vpa-130313	Vicugna pacos	57.32	3.00e-142	498.00
IUUC-Xtr-132115	Xenopus tropicalis	45.42	7.00e-105	374.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence