iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067952

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02036181

Gene Name

UBE3B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000009400.2	ENSMLUT00000009428.2	ENSMLUP00000008594.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	4.10e-113	378.2	703	1068

Active Site

Position(s)	Description	Evidence
1036	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           ++++k +++v+fv+     E+g+d++Gv++efl++++k++++p l+lf+++++d++ l+p+p+s++++ ++l+lFef+G++lgka++
   Q: 703  QHAMKGVIRVKFVNdlgvdEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDER-LYPSPTSYIHE-NYLQLFEFVGKMLGKAVY 787
           7899********************************************99987665.59*******76.****************** PP
   S: 84   dgrlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           +g ++d+p++++f+++llg+       s+++l+++d+e+yk+l++ik++ + di++lgl+l++  +e+++g+  ++eL+pgG++ipV
   Q: 788  EGIVVDVPFASFFLSQLLGHhhsvfYSSVDELPSLDSEFYKNLTSIKRY-DGDISDLGLTLSY--DEDVMGQLVCHELIPGGKTIPV 871
           ********************777777999********************.7799998777776..5999****************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwe 251
           tneNk +Y++l++++r++++ik+q++a+ +Gf+++i++e+ ++F++ el+ li+G+ +eid+edlkk+t y gg++ ++++i+w+w+
   Q: 872  TNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWTRMFSTPELQRLISGDnAEIDLEDLKKHTVYYGGFHGSHRVIIWLWD 958
           ********************************************************9****************************** PP
   S: 252  vl.eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPeY 313
           +l ++f+ +er++fL+FvT++sr Pl Gfa+lk                        + +f+irk +   rlP+s+TCfn+LkLP+Y
   Q: 959  ILaSDFTPNERAMFLKFVTSCSRPPLLGFAYLKppfsircvevsddqdtgdtlgsvlRGFFTIRKREPGGRLPTSSTCFNLLKLPNY 1045
           **99*************************************************************8888****************** PP
   S: 314  sskeilkekLlyAieetkgFels 336
           s+k++l+ekL+yAi++++gFels
   Q: 1046 SKKSVLREKLRYAISMNTGFELS 1068
           ********************985 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MFTVSQTSRA WFIDRARQAR EERLVQRERE RAAIGIQARV RSFLCRRRLQ RDIRREIDEF 60
FKADDAGSSR RSALCIFKIA RKLLFLFRMK EDNERFEKLC RCILSSMDAE NEPKVWYVSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTCACCG TTTCTCAGAC CTCGCGAGCG TGGTTCATCG ATAGAGCCCG GCAGGCTCGG 60
GAGGAAAGGC TGGTGCAGAG GGAGCGGGAG CGGGCGGCCA TCGGGATTCA GGCCCGCGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS
IPR027401--Myosin-like_IQ_dom

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	39.43	1.00e-105	378.00
IUUC-Aml-002107	Ailuropoda melanoleuca	96.54	0.00e+00	2073.00
IUUC-Atr-003017	Amborella trichopoda	38.30	8.00e-110	392.00
IUUC-Apl-003328	Anas platyrhynchos	89.95	0.00e+00	1855.00
IUUC-Aly-005794	Arabidopsis lyrata	38.93	4.00e-109	389.00
IUUC-Ath-007269	Arabidopsis thaliana	39.29	8.00e-112	398.00
IUUC-Bta-013547	Bos taurus	95.32	0.00e+00	2091.00
IUUC-Bdi-014502	Brachypodium distachyon	38.97	8.00e-110	392.00
IUUC-Bol-015093	Brassica oleracea	40.00	5.00e-113	402.00
IUUC-Bra-016722	Brassica rapa	40.00	5.00e-114	405.00
IUUC-Cel-018447	Caenorhabditis elegans	39.07	0.00e+00	682.00
IUUC-Cja-019855	Callithrix jacchus	95.22	0.00e+00	2050.00
IUUC-Cfa-020066	Canis familiaris	96.31	0.00e+00	2049.00
IUUC-Cpo-021504	Cavia porcellus	93.54	0.00e+00	2043.00
IUUC-Csa-023579	Chlorocebus sabaeus	95.42	0.00e+00	2048.00
IUUC-Cho-024430	Choloepus hoffmanni	85.06	0.00e+00	1533.00
IUUC-Cin-025750	Ciona intestinalis	47.62	0.00e+00	972.00
IUUC-Csv-026016	Ciona savignyi	48.23	0.00e+00	1016.00
IUUC-Dre-028271	Danio rerio	81.87	0.00e+00	1753.00
IUUC-Dno-029054	Dasypus novemcinctus	95.79	0.00e+00	2059.00
IUUC-Dor-030938	Dipodomys ordii	87.08	0.00e+00	1842.00
IUUC-Dme-031602	Drosophila melanogaster	48.20	0.00e+00	956.00
IUUC-Ete-033041	Echinops telfairi	76.39	0.00e+00	1350.00
IUUC-Eca-034411	Equus caballus	96.82	0.00e+00	2077.00
IUUC-Eeu-035201	Erinaceus europaeus	85.34	0.00e+00	810.00
IUUC-Fca-036594	Felis catus	94.86	0.00e+00	2037.00
IUUC-Fal-037317	Ficedula albicollis	84.84	0.00e+00	1854.00
IUUC-Gmo-039412	Gadus morhua	78.03	0.00e+00	1717.00
IUUC-Gga-040149	Gallus gallus	88.50	0.00e+00	1879.00
IUUC-Gac-042088	Gasterosteus aculeatus	81.14	0.00e+00	1810.00
IUUC-Gma-043839	Glycine max	39.61	4.00e-111	396.00
IUUC-Ggo-045279	Gorilla gorilla	95.60	0.00e+00	2048.00
IUUC-Hsa-045660	Homo sapiens	95.42	0.00e+00	2044.00
IUUC-Hvu-047102	Hordeum vulgare	35.86	6.00e-106	379.00
IUUC-Itr-048021	Ictidomys tridecemlineatus	92.07	0.00e+00	1028.00
IUUC-Lch-050664	Latimeria chalumnae	82.63	0.00e+00	1817.00
IUUC-Lpe-050755	Leersia perrieri	37.04	2.00e-98	353.00
IUUC-Loc-052791	Lepisosteus oculatus	83.32	0.00e+00	1787.00
IUUC-Laf-053902	Loxodonta africana	95.70	0.00e+00	2061.00
IUUC-Mcc-054730	Macaca mulatta	95.32	0.00e+00	2047.00
IUUC-Meu-056527	Macropus eugenii	80.04	0.00e+00	1662.00
IUUC-Mtr-057671	Medicago truncatula	39.79	1.00e-111	398.00
IUUC-Mga-059260	Meleagris gallopavo	88.15	0.00e+00	1876.00
IUUC-Mmr-060804	Microcebus murinus	95.14	0.00e+00	1999.00
IUUC-Mdo-062575	Monodelphis domestica	84.31	0.00e+00	1783.00
IUUC-Mmu-063636	Mus musculus	91.78	0.00e+00	1922.00
IUUC-Mac-064989	Musa acuminata	39.36	3.00e-107	383.00
IUUC-Mpu-066677	Mustela putorius furo	96.22	0.00e+00	1941.00
IUUC-Nle-069153	Nomascus leucogenys	95.32	0.00e+00	2042.00
IUUC-Opr-070554	Ochotona princeps	94.08	0.00e+00	1864.00
IUUC-Ont-071372	Oreochromis niloticus	82.32	0.00e+00	1788.00
IUUC-Oan-073327	Ornithorhynchus anatinus	71.21	0.00e+00	739.00
IUUC-Ocu-074183	Oryctolagus cuniculus	94.77	0.00e+00	2019.00
IUUC-Oba-075213	Oryza barthii	38.65	2.00e-106	380.00
IUUC-Obr-076320	Oryza brachyantha	35.43	4.00e-109	389.00
IUUC-Ogl-077093	Oryza glaberrima	38.92	6.00e-109	389.00
IUUC-Ogu-078947	Oryza glumaepatula	36.81	1.00e-109	391.00
IUUC-Oin-080058	Oryza indica	38.92	6.00e-109	389.00
IUUC-Olo-080742	Oryza longistaminata	35.23	5.00e-108	386.00
IUUC-Ome-081741	Oryza meridionalis	34.77	1.00e-101	365.00
IUUC-Oni-082385	Oryza nivara	36.81	8.00e-110	391.00
IUUC-Opu-083529	Oryza punctata	38.82	5.00e-109	389.00
IUUC-Oru-085128	Oryza rufipogon	37.18	2.00e-95	343.00
IUUC-Osa-085557	Oryza sativa	38.92	2.00e-108	387.00
IUUC-Ola-087337	Oryzias latipes	81.10	0.00e+00	1721.00
IUUC-Oga-088342	Otolemur garnettii	94.86	0.00e+00	1969.00
IUUC-Oar-090234	Ovis aries	95.27	0.00e+00	2068.00
IUUC-Ptr-091661	Pan troglodytes	95.60	0.00e+00	2048.00
IUUC-Pan-092728	Papio anubis	95.14	0.00e+00	2041.00
IUUC-Psi-093251	Pelodiscus sinensis	88.18	0.00e+00	1737.00
IUUC-Pma-094195	Petromyzon marinus	70.76	0.00e+00	1447.00
IUUC-Ppa-095544	Physcomitrella patens	37.87	9.00e-110	392.00
IUUC-Pfo-097472	Poecilia formosa	81.76	0.00e+00	1792.00
IUUC-Pab-098570	Pongo abelii	95.32	0.00e+00	2045.00
IUUC-Pca-100110	Procavia capensis	83.54	0.00e+00	1736.00
IUUC-Ppe-101281	Prunus persica	39.01	2.00e-107	384.00
IUUC-Pva-102887	Pteropus vampyrus	91.31	0.00e+00	1925.00
IUUC-Rno-106028	Rattus norvegicus	88.14	0.00e+00	1822.00
IUUC-Sha-107331	Sarcophilus harrisii	84.98	0.00e+00	1804.00
IUUC-Smo-109488	Selaginella moellendorffii	36.96	1.00e-105	378.00
IUUC-Sit-109811	Setaria italica	35.61	4.00e-111	395.00
IUUC-Sar-113287	Sorex araneus	84.35	0.00e+00	707.00
IUUC-Sbi-114433	Sorghum bicolor	35.29	2.00e-110	394.00
IUUC-Ssc-116103	Sus scrofa	96.07	0.00e+00	2056.00
IUUC-Tgu-117275	Taeniopygia guttata	88.04	0.00e+00	1860.00
IUUC-Tru-118681	Takifugu rubripes	80.82	0.00e+00	1801.00
IUUC-Tsy-118985	Tarsius syrichta	90.00	0.00e+00	1006.00
IUUC-Tni-120850	Tetraodon nigroviridis	91.48	0.00e+00	775.00
IUUC-Tca-121770	Theobroma cacao	39.18	2.00e-111	397.00
IUUC-Tae-125466	Triticum aestivum	36.51	3.00e-107	383.00
IUUC-Tur-126086	Triticum urartu	39.43	3.00e-105	377.00
IUUC-Tbe-127461	Tupaia belangeri	90.74	0.00e+00	1885.00
IUUC-Ttr-129269	Tursiops truncatus	95.79	0.00e+00	2041.00
IUUC-Vpa-130523	Vicugna pacos	75.40	5.00e-126	445.00
IUUC-Vvi-131524	Vitis vinifera	39.04	4.00e-109	389.00
IUUC-Xtr-132146	Xenopus tropicalis	83.77	0.00e+00	1827.00
IUUC-Xma-133526	Xiphophorus maculatus	81.57	0.00e+00	1790.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence