iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-022388

Ensembl Protein ID

ENSCPOP00000004364.2

UniProt Accession

H0V435; H0V435_CAVPO

Genbank Protein ID

ENSCPOP00000004364

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02016649

Gene Name

UBQLN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000004849.3	ENSCPOT00000004901.2	ENSCPOP00000004364.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	4.30e-10	39.4	547	584
ULD/UDP/UBQ/UBQ_PIM	4.30e-25	87.4	37	110

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyLl 39
           ++++leql +MGF +re++lqaL a++++++aA+e+Ll
   Q: 547  FQQQLEQLSAMGFlNREANLQALIATGGDINAAIERLL 584
           799**********************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           mk+tvkt+k+ke e+ v e+++v+++Ke+i+k+++ + +q+ LI+aGkiLkD++tLs++gi+dg +vhlv+k+++
   Q: 37   MKVTVKTPKEKE-EFAVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQN 110
           99**********.***********************************************************987 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MAESGESGGP PGSQDNAATA EDAGAPSAAA STEPKIMKVT VKTPKEKEEF AVPENSSVQQ 60
FKEEISKRFK SHTDQLVLIF AGKILKDQDT LSQHGIHDGL TVHLVIKTQN RSQDHSAQQT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGAGA GTGGAGAGAG CGGCGGCCCT CCAGGCTCAC AGGACAACGC TGCCACGGCC 60
GAAGATGCCG GCGCCCCCTC GGCCGCGGCC TCTACGGAGC CCAAGATCAT GAAAGTCACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0016235--C:aggresome
GO:0005776--C:autophagosome
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0035973--P:aggrephagy
GO:0000045--P:autophagosome assembly
GO:0097352--P:autophagosome maturation
GO:0071456--P:cellular response to hypoxia
GO:1901340--P:negative regulation of store-operated calcium channel activity
GO:0034140--P:negative regulation of toll-like receptor 3 signaling pathway
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:0031398--P:positive regulation of protein ubiquitination
GO:1902175--P:regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000864	Aegilops tauschii	49.65	7.00e-38	151.00
IUUC-Aml-001461	Ailuropoda melanoleuca	93.30	0.00e+00	809.00
IUUC-Atr-002470	Amborella trichopoda	39.93	2.00e-44	173.00
IUUC-Apl-003241	Anas platyrhynchos	82.46	0.00e+00	721.00
IUUC-Aca-004511	Anolis carolinensis	79.75	0.00e+00	723.00
IUUC-Aly-005419	Arabidopsis lyrata	34.51	2.00e-49	189.00
IUUC-Ath-007271	Arabidopsis thaliana	35.67	4.00e-53	202.00
IUUC-Ame-011329	Astyanax mexicanus	62.78	6.00e-153	534.00
IUUC-Bta-013048	Bos taurus	92.67	0.00e+00	830.00
IUUC-Bol-015326	Brassica oleracea	35.10	4.00e-49	189.00
IUUC-Bra-018014	Brassica rapa	38.06	9.00e-42	164.00
IUUC-Cel-018631	Caenorhabditis elegans	39.23	1.00e-67	250.00
IUUC-Cja-019976	Callithrix jacchus	95.68	0.00e+00	840.00
IUUC-Cfa-020092	Canis familiaris	93.69	0.00e+00	828.00
IUUC-Csa-024087	Chlorocebus sabaeus	95.99	0.00e+00	835.00
IUUC-Cho-024834	Choloepus hoffmanni	94.15	0.00e+00	837.00
IUUC-Cin-025136	Ciona intestinalis	50.92	6.00e-113	400.00
IUUC-Csv-026009	Ciona savignyi	52.13	3.00e-101	362.00
IUUC-Cne-026833	Cryptococcus neoformans	28.28	1.00e-13	70.50
IUUC-Cme-027155	Cyanidioschyzon merolae	58.10	1.00e-34	140.00
IUUC-Dno-028970	Dasypus novemcinctus	76.11	0.00e+00	661.00
IUUC-Dor-030519	Dipodomys ordii	93.71	0.00e+00	803.00
IUUC-Dse-031421	Dothistroma septosporum	28.57	9.00e-11	61.60
IUUC-Dme-032013	Drosophila melanogaster	46.39	2.00e-113	402.00
IUUC-Ete-032273	Echinops telfairi	92.44	0.00e+00	805.00
IUUC-Eca-033667	Equus caballus	92.53	0.00e+00	832.00
IUUC-Eeu-034865	Erinaceus europaeus	68.90	2.00e-155	542.00
IUUC-Fca-036179	Felis catus	90.29	0.00e+00	788.00
IUUC-Fal-037642	Ficedula albicollis	81.80	0.00e+00	780.00
IUUC-Gga-041264	Gallus gallus	82.45	0.00e+00	810.00
IUUC-Gma-042681	Glycine max	36.73	6.00e-45	175.00
IUUC-Ggo-044969	Gorilla gorilla	96.04	0.00e+00	814.00
IUUC-Hsa-046669	Homo sapiens	96.22	0.00e+00	846.00
IUUC-Itr-048337	Ictidomys tridecemlineatus	96.71	0.00e+00	687.00
IUUC-Lch-050192	Latimeria chalumnae	77.82	0.00e+00	678.00
IUUC-Lpe-051401	Leersia perrieri	37.86	3.00e-37	149.00
IUUC-Loc-052846	Lepisosteus oculatus	77.98	0.00e+00	671.00
IUUC-Lma-053152	Leptosphaeria maculans	30.86	6.00e-12	65.50
IUUC-Laf-054278	Loxodonta africana	91.68	0.00e+00	796.00
IUUC-Mcc-055680	Macaca mulatta	96.40	0.00e+00	846.00
IUUC-Meu-056414	Macropus eugenii	79.64	3.00e-156	545.00
IUUC-Mtr-058674	Medicago truncatula	34.58	1.00e-39	157.00
IUUC-Mga-059894	Meleagris gallopavo	82.44	0.00e+00	648.00
IUUC-Mmr-061094	Microcebus murinus	95.14	0.00e+00	828.00
IUUC-Mdo-062728	Monodelphis domestica	85.19	0.00e+00	780.00
IUUC-Mmu-064088	Mus musculus	86.15	0.00e+00	836.00
IUUC-Mac-065526	Musa acuminata	32.47	9.00e-44	171.00
IUUC-Mpu-066282	Mustela putorius furo	91.01	0.00e+00	800.00
IUUC-Mlu-068158	Myotis lucifugus	92.79	0.00e+00	795.00
IUUC-Nle-069321	Nomascus leucogenys	96.22	0.00e+00	846.00
IUUC-Opr-071098	Ochotona princeps	87.35	0.00e+00	628.00
IUUC-Oan-072808	Ornithorhynchus anatinus	85.90	0.00e+00	738.00
IUUC-Ocu-074301	Oryctolagus cuniculus	86.78	0.00e+00	791.00
IUUC-Oba-074973	Oryza barthii	38.19	1.00e-43	170.00
IUUC-Obr-076444	Oryza brachyantha	50.34	1.00e-32	134.00
IUUC-Ogl-077319	Oryza glaberrima	38.51	3.00e-44	172.00
IUUC-Ogu-078074	Oryza glumaepatula	34.53	6.00e-51	195.00
IUUC-Oin-079142	Oryza indica	38.51	8.00e-45	174.00
IUUC-Olo-080565	Oryza longistaminata	34.75	2.00e-49	189.00
IUUC-Ome-081155	Oryza meridionalis	51.55	3.00e-34	139.00
IUUC-Oni-082272	Oryza nivara	38.51	8.00e-45	174.00
IUUC-Opu-083241	Oryza punctata	35.54	6.00e-52	198.00
IUUC-Oru-085257	Oryza rufipogon	38.51	8.00e-45	174.00
IUUC-Osa-086257	Oryza sativa	38.51	3.00e-44	172.00
IUUC-Ola-086802	Oryzias latipes	67.38	1.00e-135	477.00
IUUC-Olu-087597	Ostreococcus lucimarinus	31.75	1.00e-25	110.00
IUUC-Oga-088495	Otolemur garnettii	94.59	0.00e+00	804.00
IUUC-Oar-089711	Ovis aries	92.02	0.00e+00	806.00
IUUC-Ptr-091439	Pan troglodytes	95.86	0.00e+00	840.00
IUUC-Pan-092641	Papio anubis	96.40	0.00e+00	846.00
IUUC-Psi-093518	Pelodiscus sinensis	82.21	0.00e+00	717.00
IUUC-Pma-094727	Petromyzon marinus	43.26	9.00e-54	204.00
IUUC-Ppa-095193	Physcomitrella patens	52.80	2.00e-35	144.00
IUUC-Pfo-096638	Poecilia formosa	67.26	5.00e-175	607.00
IUUC-Pab-098699	Pongo abelii	93.87	0.00e+00	838.00
IUUC-Pop-099549	Populus trichocarpa	41.55	2.00e-48	186.00
IUUC-Pca-100497	Procavia capensis	83.52	4.00e-134	471.00
IUUC-Ppe-101901	Prunus persica	34.70	2.00e-56	213.00
IUUC-Pva-102513	Pteropus vampyrus	81.50	3.00e-146	511.00
IUUC-Rno-104908	Rattus norvegicus	85.47	0.00e+00	867.00
IUUC-Sha-106881	Sarcophilus harrisii	82.84	0.00e+00	697.00
IUUC-Smo-108910	Selaginella moellendorffii	35.24	7.00e-39	155.00
IUUC-Sit-110766	Setaria italica	38.76	2.00e-36	147.00
IUUC-Sly-111731	Solanum lycopersicum	40.32	2.00e-41	163.00
IUUC-Sar-113648	Sorex araneus	88.52	1.00e-180	625.00
IUUC-Sbi-114307	Sorghum bicolor	38.80	2.00e-45	176.00
IUUC-Ssc-115820	Sus scrofa	94.59	0.00e+00	831.00
IUUC-Tgu-116845	Taeniopygia guttata	76.47	0.00e+00	694.00
IUUC-Tni-119780	Tetraodon nigroviridis	65.37	5.00e-171	593.00
IUUC-Tca-121558	Theobroma cacao	34.16	3.00e-54	206.00
IUUC-Tae-125518	Triticum aestivum	49.65	2.00e-38	153.00
IUUC-Tur-126248	Triticum urartu	49.65	3.00e-38	153.00
IUUC-Tbe-127379	Tupaia belangeri	81.70	0.00e+00	671.00
IUUC-Ttr-128630	Tursiops truncatus	91.72	0.00e+00	845.00
IUUC-Vpa-130413	Vicugna pacos	70.33	7.00e-160	556.00
IUUC-Vvi-131599	Vitis vinifera	40.21	8.00e-43	168.00
IUUC-Xtr-132595	Xenopus tropicalis	79.89	0.00e+00	707.00
IUUC-Xma-134155	Xiphophorus maculatus	62.37	8.00e-163	566.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence