iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088495

Ensembl Protein ID

ENSOGAP00000011607.2

UniProt Accession

H0X831; H0X831_OTOGA

Genbank Protein ID

ENSOGAP00000011607

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03015224

Gene Name

UBQLN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000012947.2	ENSOGAT00000012953.2	ENSOGAP00000011607.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	4.40e-10	39.4	547	584
ULD/UDP/UBQ/UBQ_PIM	4.50e-25	87.4	37	110

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyLl 39
           ++++leql +MGF +re++lqaL a++++++aA+e+Ll
   Q: 547  FQQQLEQLSAMGFlNREANLQALIATGGDINAAIERLL 584
           799**********************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           mk+tvkt+k+ke e+ v e+++v+++Ke+i+k+++ + +q+ LI+aGkiLkD++tLs++gi+dg +vhlv+k+++
   Q: 37   MKVTVKTPKEKE-EFAVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQN 110
           99**********.***********************************************************987 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MAESGESGGP PGPQDSAAAA EGAGTPAAAN SAEPKIMKVT VKTPKEKEEF AVPENSSVQQ 60
FKEEISKRFK SHTDQLVLIF AGKILKDQDT LSQHGIHDGL TVHLVIKTQN RPQDHSAQQT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGAAGCGA CGGCGGCTGC GGATGTCGCT GCGAACCAGC GGCTCCTGAA CCCACGGCAG 60
CTGCCCAGTG CCCAACTTGG GCCTGCGCCG GAGCCCACGC CGAGCTCCGC GGCCCCTCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0016235--C:aggresome
GO:0005776--C:autophagosome
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0035973--P:aggrephagy
GO:0000045--P:autophagosome assembly
GO:0097352--P:autophagosome maturation
GO:0071456--P:cellular response to hypoxia
GO:1901340--P:negative regulation of store-operated calcium channel activity
GO:0034140--P:negative regulation of toll-like receptor 3 signaling pathway
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:0031398--P:positive regulation of protein ubiquitination
GO:1902175--P:regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000864	Aegilops tauschii	49.65	8.00e-38	151.00
IUUC-Aml-001461	Ailuropoda melanoleuca	94.85	0.00e+00	798.00
IUUC-Atr-002470	Amborella trichopoda	39.93	3.00e-44	173.00
IUUC-Apl-003241	Anas platyrhynchos	83.77	0.00e+00	710.00
IUUC-Aca-004511	Anolis carolinensis	80.64	0.00e+00	721.00
IUUC-Ath-007271	Arabidopsis thaliana	35.67	3.00e-52	199.00
IUUC-Ago-007963	Ashbya gossypii	37.68	1.00e-08	54.30
IUUC-Bta-013048	Bos taurus	94.21	0.00e+00	817.00
IUUC-Bol-015326	Brassica oleracea	35.67	2.00e-48	187.00
IUUC-Bra-018014	Brassica rapa	38.06	2.00e-40	159.00
IUUC-Cel-018631	Caenorhabditis elegans	38.73	2.00e-67	249.00
IUUC-Cja-019976	Callithrix jacchus	96.22	0.00e+00	832.00
IUUC-Cfa-020092	Canis familiaris	95.32	0.00e+00	821.00
IUUC-Cpo-022388	Cavia porcellus	94.59	0.00e+00	815.00
IUUC-Csa-024087	Chlorocebus sabaeus	96.90	0.00e+00	821.00
IUUC-Cho-024834	Choloepus hoffmanni	95.61	0.00e+00	831.00
IUUC-Cin-025136	Ciona intestinalis	50.74	1.00e-111	396.00
IUUC-Cme-027155	Cyanidioschyzon merolae	58.10	1.00e-34	140.00
IUUC-Dno-028970	Dasypus novemcinctus	77.43	0.00e+00	658.00
IUUC-Dor-030519	Dipodomys ordii	92.27	0.00e+00	790.00
IUUC-Dme-032013	Drosophila melanogaster	46.39	7.00e-113	400.00
IUUC-Ete-032273	Echinops telfairi	94.14	0.00e+00	795.00
IUUC-Eca-033667	Equus caballus	93.89	0.00e+00	828.00
IUUC-Fca-036179	Felis catus	92.09	0.00e+00	779.00
IUUC-Fal-037642	Ficedula albicollis	81.37	0.00e+00	771.00
IUUC-Gga-041264	Gallus gallus	82.60	0.00e+00	798.00
IUUC-Gma-043430	Glycine max	50.96	7.00e-40	158.00
IUUC-Ggo-044969	Gorilla gorilla	96.58	0.00e+00	800.00
IUUC-Hsa-046669	Homo sapiens	96.76	0.00e+00	833.00
IUUC-Itr-048337	Ictidomys tridecemlineatus	96.01	0.00e+00	677.00
IUUC-Lch-050192	Latimeria chalumnae	77.26	0.00e+00	665.00
IUUC-Lpe-051401	Leersia perrieri	36.42	2.00e-35	143.00
IUUC-Loc-052846	Lepisosteus oculatus	80.09	3.00e-167	581.00
IUUC-Laf-054278	Loxodonta africana	93.38	0.00e+00	794.00
IUUC-Mcc-055680	Macaca mulatta	97.30	0.00e+00	833.00
IUUC-Meu-056207	Macropus eugenii	74.36	4.00e-174	604.00
IUUC-Mtr-058674	Medicago truncatula	36.68	1.00e-46	181.00
IUUC-Mga-059894	Meleagris gallopavo	84.45	0.00e+00	639.00
IUUC-Mmr-061094	Microcebus murinus	97.12	0.00e+00	823.00
IUUC-Mdo-062728	Monodelphis domestica	85.35	0.00e+00	776.00
IUUC-Mmu-064088	Mus musculus	86.15	0.00e+00	823.00
IUUC-Mac-065458	Musa acuminata	39.27	8.00e-38	151.00
IUUC-Mpu-066282	Mustela putorius furo	91.55	0.00e+00	792.00
IUUC-Mlu-068158	Myotis lucifugus	93.15	0.00e+00	782.00
IUUC-Nle-069321	Nomascus leucogenys	96.58	0.00e+00	833.00
IUUC-Opr-071098	Ochotona princeps	88.54	3.00e-178	617.00
IUUC-Oan-072808	Ornithorhynchus anatinus	86.09	0.00e+00	728.00
IUUC-Ocu-074301	Oryctolagus cuniculus	86.98	0.00e+00	781.00
IUUC-Oba-074973	Oryza barthii	38.28	9.00e-42	164.00
IUUC-Obr-076444	Oryza brachyantha	50.34	2.00e-32	134.00
IUUC-Ogl-077319	Oryza glaberrima	38.28	2.00e-42	167.00
IUUC-Ogu-078074	Oryza glumaepatula	35.00	7.00e-50	191.00
IUUC-Oin-079142	Oryza indica	38.03	3.00e-42	166.00
IUUC-Olo-080565	Oryza longistaminata	35.00	1.00e-47	184.00
IUUC-Ome-081155	Oryza meridionalis	51.55	4.00e-34	139.00
IUUC-Oni-082272	Oryza nivara	38.03	3.00e-42	166.00
IUUC-Opu-083241	Oryza punctata	35.57	1.00e-49	191.00
IUUC-Oru-085257	Oryza rufipogon	38.03	3.00e-42	166.00
IUUC-Osa-086257	Oryza sativa	38.28	2.00e-42	166.00
IUUC-Olu-087597	Ostreococcus lucimarinus	32.48	5.00e-25	108.00
IUUC-Oar-089711	Ovis aries	93.55	0.00e+00	800.00
IUUC-Ptr-091439	Pan troglodytes	96.40	0.00e+00	827.00
IUUC-Pan-092641	Papio anubis	97.30	0.00e+00	833.00
IUUC-Psi-093518	Pelodiscus sinensis	82.21	0.00e+00	706.00
IUUC-Pma-094727	Petromyzon marinus	42.92	8.00e-52	197.00
IUUC-Ppa-095193	Physcomitrella patens	52.80	2.00e-35	143.00
IUUC-Pfo-096638	Poecilia formosa	67.68	1.00e-173	602.00
IUUC-Pab-098699	Pongo abelii	94.77	0.00e+00	830.00
IUUC-Pop-099549	Populus trichocarpa	37.56	9.00e-54	204.00
IUUC-Pca-100497	Procavia capensis	83.24	7.00e-132	464.00
IUUC-Pva-102513	Pteropus vampyrus	93.83	9.00e-131	460.00
IUUC-Rno-104908	Rattus norvegicus	86.82	0.00e+00	852.00
IUUC-Sha-106881	Sarcophilus harrisii	82.46	0.00e+00	689.00
IUUC-Smo-108910	Selaginella moellendorffii	36.15	1.00e-37	150.00
IUUC-Sit-110766	Setaria italica	37.58	1.00e-35	144.00
IUUC-Sar-113648	Sorex araneus	87.47	6.00e-179	620.00
IUUC-Sbi-114307	Sorghum bicolor	37.87	3.00e-42	166.00
IUUC-Ssc-115820	Sus scrofa	95.68	0.00e+00	823.00
IUUC-Tgu-116845	Taeniopygia guttata	77.01	0.00e+00	682.00
IUUC-Tni-119780	Tetraodon nigroviridis	64.96	3.00e-171	595.00
IUUC-Tca-121558	Theobroma cacao	34.16	1.00e-52	201.00
IUUC-Tae-125518	Triticum aestivum	49.65	2.00e-38	153.00
IUUC-Tur-126248	Triticum urartu	49.65	3.00e-38	153.00
IUUC-Tbe-127379	Tupaia belangeri	83.21	0.00e+00	664.00
IUUC-Ttr-128630	Tursiops truncatus	92.57	0.00e+00	835.00
IUUC-Vpa-130413	Vicugna pacos	70.73	1.00e-156	546.00
IUUC-Vvi-131599	Vitis vinifera	39.25	4.00e-41	162.00
IUUC-Xtr-132595	Xenopus tropicalis	79.35	0.00e+00	695.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence