iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004699

Ensembl Protein ID

ENSACAP00000021254.1

UniProt Accession

G1KYX2; G1KYX2_ANOCA

Protein Name

Uncharacterized protein

Gene Name

SQSTM1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000016080.3	ENSACAT00000023663.1	ENSACAP00000021254.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	45.76	1.00e-08	58.50	IUUC-Dme-031659
UBD/Alpha-Helix/UBA	47.81	2.00e-93	340.00	IUUC-Hsa-046390
ULD/UDP/UFD/PB1	47.81	2.00e-93	340.00	IUUC-Hsa-046390
UBD/Alpha-Helix/UBA	49.24	8.00e-99	358.00	IUUC-Mmu-063589
UBD/Alpha-Helix/UBA	49.24	6.00e-96	348.00	IUUC-Rno-105539

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MAPLTVKAYL LGKEEVTREI RRFALDRPPR FQPIRDKVAE LFQGLLRNAS PGPAGAFQMY 60
YKDEDGDTIA FSSDEELKLA LPCVKDGVFR IYVKEKKELK REHLHRQSCS QERPSNVVHP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCCCGC TGACGGTAAA GGCCTACCTG CTGGGCAAGG AAGAAGTCAC CCGAGAGATC 60
CGCCGCTTCG CCCTCGACAG GCCGCCCCGA TTCCAGCCCA TCCGCGACAA GGTGGCCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000270--PB1_dom
IPR033741--SQSTM_UBA
IPR015940--UBA
IPR009060--UBA-like
IPR000433--Znf_ZZ

PROSITE

PS51745--PB1
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF00564--PB1
PF16577--UBA_5
PF00569--ZZ

SMART

SM00666--PB1
SM00165--UBA
SM00291--ZnF_ZZ

Gene Ontology

GO:0016235--C:aggresome
GO:0044753--C:amphisome
GO:0044754--C:autolysosome
GO:0005776--C:autophagosome
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0000932--C:P-body
GO:0016605--C:PML body
GO:0000407--C:pre-autophagosomal structure
GO:0097225--C:sperm midpiece
GO:0042802--F:identical protein binding
GO:0043130--F:ubiquitin binding
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0044130--P:negative regulation of growth of symbiont in host
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0016239--P:positive regulation of macroautophagy
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043122--P:regulation of I-kappaB kinase/NF-kappaB signaling
GO:0061635--P:regulation of protein complex stability
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001367	Ailuropoda melanoleuca	47.52	4.00e-87	314.00
IUUC-Apl-003897	Anas platyrhynchos	53.28	1.00e-108	386.00
IUUC-Ame-010982	Astyanax mexicanus	49.68	1.00e-32	134.00
IUUC-Bta-012634	Bos taurus	48.25	5.00e-103	367.00
IUUC-Cel-018660	Caenorhabditis elegans	54.55	2.00e-12	65.10
IUUC-Cja-019684	Callithrix jacchus	48.66	4.00e-101	361.00
IUUC-Cfa-020573	Canis familiaris	41.54	8.00e-62	230.00
IUUC-Cpo-021425	Cavia porcellus	47.70	2.00e-98	352.00
IUUC-Csa-023968	Chlorocebus sabaeus	47.47	2.00e-96	346.00
IUUC-Cho-024596	Choloepus hoffmanni	34.78	4.00e-13	68.60
IUUC-Cin-025557	Ciona intestinalis	31.53	1.00e-16	80.10
IUUC-Csv-025974	Ciona savignyi	28.68	1.00e-15	77.00
IUUC-Cne-027045	Cryptococcus neoformans	35.71	3.00e-09	57.80
IUUC-Dre-028621	Danio rerio	45.07	9.00e-60	224.00
IUUC-Dno-029060	Dasypus novemcinctus	46.10	7.00e-100	357.00
IUUC-Dor-030547	Dipodomys ordii	52.58	6.00e-77	281.00
IUUC-Dme-031659	Drosophila melanogaster	31.71	7.00e-11	62.00
IUUC-Ete-033201	Echinops telfairi	45.81	2.00e-77	282.00
IUUC-Eca-033456	Equus caballus	49.75	1.00e-93	336.00
IUUC-Eeu-035157	Erinaceus europaeus	47.66	2.00e-87	315.00
IUUC-Fca-035403	Felis catus	46.32	3.00e-98	352.00
IUUC-Fal-036798	Ficedula albicollis	57.20	4.00e-134	471.00
IUUC-Gmo-039619	Gadus morhua	42.39	1.00e-55	209.00
IUUC-Gga-040137	Gallus gallus	56.93	2.00e-130	459.00
IUUC-Gac-042410	Gasterosteus aculeatus	39.56	6.00e-82	297.00
IUUC-Ggo-044690	Gorilla gorilla	47.59	3.00e-97	348.00
IUUC-Hsa-046390	Homo sapiens	47.81	2.00e-97	349.00
IUUC-Itr-048536	Ictidomys tridecemlineatus	47.82	9.00e-103	367.00
IUUC-Lch-049658	Latimeria chalumnae	42.89	8.00e-96	343.00
IUUC-Loc-052589	Lepisosteus oculatus	45.05	7.00e-97	347.00
IUUC-Laf-053746	Loxodonta africana	44.25	4.00e-85	308.00
IUUC-Mcc-055635	Macaca mulatta	47.36	8.00e-99	353.00
IUUC-Meu-056528	Macropus eugenii	44.75	2.00e-56	213.00
IUUC-Mga-059458	Meleagris gallopavo	53.73	6.00e-106	377.00
IUUC-Mmr-061539	Microcebus murinus	46.36	2.00e-68	252.00
IUUC-Mdo-063083	Monodelphis domestica	50.11	3.00e-107	382.00
IUUC-Mmu-063589	Mus musculus	49.46	4.00e-103	367.00
IUUC-Mpu-065727	Mustela putorius furo	48.96	3.00e-91	328.00
IUUC-Mlu-067026	Myotis lucifugus	49.34	3.00e-93	335.00
IUUC-Nle-069356	Nomascus leucogenys	32.55	2.00e-39	155.00
IUUC-Opr-071091	Ochotona princeps	44.44	2.00e-53	202.00
IUUC-Ont-071864	Oreochromis niloticus	42.83	1.00e-89	323.00
IUUC-Oan-073308	Ornithorhynchus anatinus	48.34	1.00e-96	346.00
IUUC-Ocu-074110	Oryctolagus cuniculus	47.91	5.00e-100	357.00
IUUC-Ola-086944	Oryzias latipes	40.00	1.00e-28	119.00
IUUC-Oga-088869	Otolemur garnettii	46.62	8.00e-99	353.00
IUUC-Oar-089857	Ovis aries	49.34	2.00e-91	329.00
IUUC-Ptr-091640	Pan troglodytes	47.81	2.00e-97	348.00
IUUC-Pan-092831	Papio anubis	47.16	2.00e-96	345.00
IUUC-Psi-093925	Pelodiscus sinensis	55.75	1.00e-122	432.00
IUUC-Pma-094576	Petromyzon marinus	31.69	1.00e-44	173.00
IUUC-Ppa-095342	Physcomitrella patens	50.00	1.00e-06	47.00
IUUC-Pfo-097297	Poecilia formosa	39.33	2.00e-80	293.00
IUUC-Pab-098725	Pongo abelii	44.32	2.00e-87	316.00
IUUC-Pca-101106	Procavia capensis	48.32	2.00e-95	342.00
IUUC-Pva-102710	Pteropus vampyrus	49.32	5.00e-73	268.00
IUUC-Rno-105539	Rattus norvegicus	49.24	5.00e-103	367.00
IUUC-Sha-107469	Sarcophilus harrisii	49.23	3.00e-92	331.00
IUUC-Ssc-115526	Sus scrofa	47.37	5.00e-102	364.00
IUUC-Tgu-116607	Taeniopygia guttata	63.03	1.00e-112	399.00
IUUC-Tru-117896	Takifugu rubripes	43.27	2.00e-90	325.00
IUUC-Tni-119943	Tetraodon nigroviridis	40.80	2.00e-75	275.00
IUUC-Ttr-128676	Tursiops truncatus	49.13	2.00e-103	369.00
IUUC-Vda-129812	Verticillium dahliae	47.27	1.00e-07	51.60
IUUC-Vpa-130319	Vicugna pacos	66.67	4.00e-40	157.00
IUUC-Xtr-132907	Xenopus tropicalis	50.76	2.00e-117	416.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence