iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-055635

Ensembl Protein ID

ENSMMUP00000033598.2

UniProt Accession

F7GSB8; H9ZEV6; F7GSB8_MACMU

Genbank Protein ID

AFH34472.1

Protein Name

Sequestosome-1 isoform 1

Genbank Nucleotide ID

JSUE03037699

Gene Name

SQSTM1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000021055.3	ENSMMUT00000040542.2	ENSMMUP00000033598.2
ENSMMUG00000021055.3	ENSMMUT00000029609.3	ENSMMUP00000027709.3
ENSMMUG00000021055.3	ENSMMUT00000075495.1	ENSMMUP00000060712.1
ENSMMUG00000021055.3	ENSMMUT00000067763.1	ENSMMUP00000042580.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/PB1	2.00e-18	67.4	22	102

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/PB1

   S: 3    rvkvsykgeirsfaldlekpgkfedLlkavrt.ltelknsevalkYeDedGDlvtlksDedldkavsllaskksllrlliqkk 84
           r+ +++++e+++ a+d+++pg +e+Ll++v++ +++l+   ++ +Y+DedGDlv+++sDe+l++a+s+   k++++r++i++k
   Q: 22   RFSFCFSPEPEAEAEDAAGPGPCERLLSRVAAlFPALRPGGFQAHYRDEDGDLVAFSSDEELTMAMSY--VKDDIFRIYIKEK 102
           899*****************************999********************************7..9*********975 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MASLTVKAYL LGKEDAAREI RRFSFCFSPE PEAEAEDAAG PGPCERLLSR VAALFPALRP 60
GGFQAHYRDE DGDLVAFSSD EELTMAMSYV KDDIFRIYIK EKKECRRDHR PPCAQEAPRN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGCGACCCG GACGGCCAGT TTTCCGCAGC TCGCCCTCGC TATGGCGTCG CTCACCGTGA 60
AGGCCTACCT GCTGGGCAAG GAGGACGCGG CGCGCGAGAT CCGCCGCTTC AGCTTCTGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000270--PB1_dom
IPR033741--SQSTM_UBA
IPR015940--UBA
IPR009060--UBA-like
IPR000433--Znf_ZZ

PROSITE

PS51745--PB1
PS50030--UBA
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF00564--PB1
PF16577--UBA_5
PF00569--ZZ

SMART

SM00666--PB1
SM00165--UBA
SM00291--ZnF_ZZ

Gene Ontology

GO:0016235--C:aggresome
GO:0044753--C:amphisome
GO:0044754--C:autolysosome
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0000932--C:P-body
GO:0016605--C:PML body
GO:0000407--C:pre-autophagosomal structure
GO:0097225--C:sperm midpiece
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0044130--P:negative regulation of growth of symbiont in host
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045071--P:negative regulation of viral genome replication
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043122--P:regulation of I-kappaB kinase/NF-kappaB signaling
GO:0061635--P:regulation of protein complex stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001367	Ailuropoda melanoleuca	90.30	2.00e-171	594.00
IUUC-Apl-003897	Anas platyrhynchos	59.26	8.00e-118	416.00
IUUC-Aca-004699	Anolis carolinensis	48.15	4.00e-97	348.00
IUUC-Ame-010982	Astyanax mexicanus	44.55	1.00e-64	240.00
IUUC-Bta-012634	Bos taurus	91.59	0.00e+00	761.00
IUUC-Cel-018660	Caenorhabditis elegans	50.00	8.00e-11	60.10
IUUC-Cja-019684	Callithrix jacchus	95.44	0.00e+00	771.00
IUUC-Cfa-020573	Canis familiaris	84.07	2.00e-138	485.00
IUUC-Cpo-021425	Cavia porcellus	79.50	3.00e-179	621.00
IUUC-Csa-023968	Chlorocebus sabaeus	96.36	0.00e+00	761.00
IUUC-Cho-024596	Choloepus hoffmanni	85.16	7.00e-55	207.00
IUUC-Cin-025557	Ciona intestinalis	30.61	3.00e-13	69.30
IUUC-Csv-025974	Ciona savignyi	25.76	1.00e-13	70.50
IUUC-Dre-028621	Danio rerio	44.40	9.00e-97	347.00
IUUC-Dno-029060	Dasypus novemcinctus	87.84	0.00e+00	740.00
IUUC-Dor-030547	Dipodomys ordii	89.38	2.00e-139	488.00
IUUC-Dme-031659	Drosophila melanogaster	45.28	3.00e-08	53.50
IUUC-Ete-033201	Echinops telfairi	82.53	1.00e-166	579.00
IUUC-Eca-033456	Equus caballus	90.34	0.00e+00	686.00
IUUC-Eeu-035157	Erinaceus europaeus	83.91	3.00e-173	600.00
IUUC-Fca-035403	Felis catus	89.41	0.00e+00	711.00
IUUC-Fal-036798	Ficedula albicollis	57.66	9.00e-136	476.00
IUUC-Gmo-039619	Gadus morhua	39.60	2.00e-47	182.00
IUUC-Gga-040137	Gallus gallus	57.78	2.00e-133	469.00
IUUC-Gac-042410	Gasterosteus aculeatus	45.84	2.00e-97	349.00
IUUC-Ggo-044690	Gorilla gorilla	96.14	0.00e+00	759.00
IUUC-Hsa-046390	Homo sapiens	95.91	0.00e+00	755.00
IUUC-Itr-048536	Ictidomys tridecemlineatus	92.73	0.00e+00	783.00
IUUC-Lch-049658	Latimeria chalumnae	47.78	4.00e-113	401.00
IUUC-Loc-052589	Lepisosteus oculatus	48.24	1.00e-112	399.00
IUUC-Laf-053746	Loxodonta africana	82.29	0.00e+00	665.00
IUUC-Meu-056528	Macropus eugenii	52.75	5.00e-106	377.00
IUUC-Mga-059458	Meleagris gallopavo	59.65	9.00e-119	420.00
IUUC-Mvi-060347	Microbotryum violaceum	54.05	2.00e-07	52.40
IUUC-Mmr-061539	Microcebus murinus	90.22	1.00e-145	509.00
IUUC-Mdo-063083	Monodelphis domestica	63.80	3.00e-154	538.00
IUUC-Mmu-063589	Mus musculus	88.69	0.00e+00	759.00
IUUC-Mpu-065727	Mustela putorius furo	88.65	0.00e+00	630.00
IUUC-Mlu-067026	Myotis lucifugus	86.93	0.00e+00	634.00
IUUC-Nle-069356	Nomascus leucogenys	70.11	2.00e-130	458.00
IUUC-Opr-071091	Ochotona princeps	70.38	2.00e-98	352.00
IUUC-Ont-071864	Oreochromis niloticus	46.85	8.00e-101	360.00
IUUC-Oan-073308	Ornithorhynchus anatinus	63.72	1.00e-140	492.00
IUUC-Ocu-074110	Oryctolagus cuniculus	90.00	0.00e+00	737.00
IUUC-Ola-086944	Oryzias latipes	45.00	1.00e-39	155.00
IUUC-Oga-088869	Otolemur garnettii	88.79	0.00e+00	741.00
IUUC-Oar-089857	Ovis aries	92.00	0.00e+00	662.00
IUUC-Ptr-091640	Pan troglodytes	96.14	0.00e+00	759.00
IUUC-Pan-092831	Papio anubis	96.41	0.00e+00	767.00
IUUC-Psi-093925	Pelodiscus sinensis	56.22	3.00e-128	451.00
IUUC-Pma-094576	Petromyzon marinus	31.02	2.00e-30	126.00
IUUC-Pfo-097297	Poecilia formosa	44.20	8.00e-90	324.00
IUUC-Pab-098725	Pongo abelii	89.52	0.00e+00	670.00
IUUC-Pca-101106	Procavia capensis	89.09	0.00e+00	709.00
IUUC-Pva-102710	Pteropus vampyrus	87.44	0.00e+00	665.00
IUUC-Rno-105539	Rattus norvegicus	89.14	0.00e+00	770.00
IUUC-Sha-107469	Sarcophilus harrisii	59.07	1.00e-122	432.00
IUUC-Ssc-115526	Sus scrofa	92.95	0.00e+00	740.00
IUUC-Tgu-117194	Taeniopygia guttata	60.72	6.00e-119	420.00
IUUC-Tru-117896	Takifugu rubripes	47.19	2.00e-100	359.00
IUUC-Tni-119943	Tetraodon nigroviridis	47.07	1.00e-89	323.00
IUUC-Ttr-128676	Tursiops truncatus	91.82	0.00e+00	766.00
IUUC-Vda-129812	Verticillium dahliae	38.96	9.00e-08	52.40
IUUC-Vpa-130319	Vicugna pacos	95.00	2.00e-56	212.00
IUUC-Xtr-132907	Xenopus tropicalis	53.78	4.00e-129	454.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence