iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052904

Ensembl Protein ID

ENSLOCP00000007096.1

UniProt Accession

W5MFD7; W5MFD7_LEPOC

Genbank Protein ID

ENSLOCP00000007096

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AHAT01024384

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000005873.1	ENSLOCT00000007104.1	ENSLOCP00000007096.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.50e-17	61.6	61	117

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
             v++lydyea +d++L +kkG++++v+   +++++W+ + +  +gk+G++P+n+v+k++
   Q: 61   SIVITLYDYEAIHDGDLGFKKGEKLKVL---QESGEWWCARSLSTGKEGFIPSNYVAKVN 117
           5799************************...99*************************97 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MGCIKSKEEQ QASNDKIVNN DSVRKIQQAH YVKDPTSGSK TTQNSSSALP PSPGHTDGGE 60
SIVITLYDYE AIHDGDLGFK KGEKLKVLQE SGEWWCARSL STGKEGFIPS NYVAKVNSLE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGATCTGCG TTAGCAGTGC CGGTCACTTC CTCGTGTGTC TGACATCCCC GCTGAGCTGC 60
GTTTTACACA TCAGCGACAT GGGAACGGTG ATCTTTCACG AATAAAACGC CGTATAACAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001284	Ailuropoda melanoleuca	77.76	0.00e+00	813.00
IUUC-Apl-003285	Anas platyrhynchos	77.54	0.00e+00	823.00
IUUC-Aca-004724	Anolis carolinensis	77.45	0.00e+00	797.00
IUUC-Ame-011954	Astyanax mexicanus	84.42	0.00e+00	867.00
IUUC-Bta-013060	Bos taurus	78.35	0.00e+00	823.00
IUUC-Cja-019817	Callithrix jacchus	77.51	0.00e+00	810.00
IUUC-Cfa-020511	Canis familiaris	77.95	0.00e+00	815.00
IUUC-Cpo-022538	Cavia porcellus	76.82	0.00e+00	806.00
IUUC-Csa-024143	Chlorocebus sabaeus	78.94	0.00e+00	822.00
IUUC-Dre-028157	Danio rerio	84.02	0.00e+00	887.00
IUUC-Dno-029761	Dasypus novemcinctus	76.92	0.00e+00	823.00
IUUC-Dor-030892	Dipodomys ordii	67.86	0.00e+00	683.00
IUUC-Eca-034090	Equus caballus	77.36	0.00e+00	803.00
IUUC-Eeu-035004	Erinaceus europaeus	65.00	5.00e-145	507.00
IUUC-Fca-035937	Felis catus	76.48	0.00e+00	785.00
IUUC-Fal-036624	Ficedula albicollis	76.56	0.00e+00	816.00
IUUC-Gmo-039009	Gadus morhua	78.70	0.00e+00	824.00
IUUC-Gga-040296	Gallus gallus	76.13	0.00e+00	807.00
IUUC-Gac-042362	Gasterosteus aculeatus	81.66	0.00e+00	862.00
IUUC-Ggo-044570	Gorilla gorilla	78.11	0.00e+00	820.00
IUUC-Hsa-046378	Homo sapiens	78.30	0.00e+00	825.00
IUUC-Itr-048695	Ictidomys tridecemlineatus	77.01	0.00e+00	817.00
IUUC-Laf-053654	Loxodonta africana	78.11	0.00e+00	827.00
IUUC-Mcc-055317	Macaca mulatta	79.13	0.00e+00	829.00
IUUC-Mga-060194	Meleagris gallopavo	78.79	0.00e+00	756.00
IUUC-Mmr-061510	Microcebus murinus	77.32	0.00e+00	823.00
IUUC-Mdo-062035	Monodelphis domestica	77.84	0.00e+00	819.00
IUUC-Mmu-064037	Mus musculus	77.17	0.00e+00	823.00
IUUC-Mpu-066874	Mustela putorius furo	77.91	0.00e+00	822.00
IUUC-Mlu-068202	Myotis lucifugus	75.35	0.00e+00	784.00
IUUC-Nle-069222	Nomascus leucogenys	79.13	0.00e+00	823.00
IUUC-Opr-070705	Ochotona princeps	76.73	0.00e+00	810.00
IUUC-Ont-072347	Oreochromis niloticus	88.62	0.00e+00	816.00
IUUC-Ocu-074490	Oryctolagus cuniculus	78.35	0.00e+00	817.00
IUUC-Ola-086521	Oryzias latipes	88.64	0.00e+00	850.00
IUUC-Oga-088153	Otolemur garnettii	77.51	0.00e+00	817.00
IUUC-Oar-090184	Ovis aries	77.69	0.00e+00	815.00
IUUC-Ptr-090505	Pan troglodytes	74.56	0.00e+00	768.00
IUUC-Pan-092260	Papio anubis	79.13	0.00e+00	829.00
IUUC-Pma-094311	Petromyzon marinus	68.03	0.00e+00	726.00
IUUC-Pfo-096566	Poecilia formosa	82.71	0.00e+00	885.00
IUUC-Pva-103021	Pteropus vampyrus	78.30	0.00e+00	824.00
IUUC-Rno-105309	Rattus norvegicus	77.56	0.00e+00	825.00
IUUC-Sha-107099	Sarcophilus harrisii	76.82	0.00e+00	816.00
IUUC-Tgu-116912	Taeniopygia guttata	76.67	0.00e+00	811.00
IUUC-Tru-118449	Takifugu rubripes	85.87	0.00e+00	810.00
IUUC-Tbe-128144	Tupaia belangeri	76.91	0.00e+00	712.00
IUUC-Xtr-132224	Xenopus tropicalis	69.43	0.00e+00	692.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence