iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005057

UUCD1 version

UUC-AnC-00986

Ensembl Protein ID

ENSACAP00000014965.3

UniProt Accession

H9GM17; H9GM17_ANOCA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000015190.3	ENSACAT00000015268.3	ENSACAP00000014965.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-82	277.4	724	1305

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtC+mNS +Qc sn+++l++++ + ++  +ln++np ++kg+++k++ +l++elw++++k+++p +l  +++k+a++f+g
   Q: 724  TGLSNLGNTCFMNSSIQCVSNTQPLTQYFISgRHLYELNRTNPIGMKGHMAKCYGDLIQELWSGTQKNIAPLKLRWTIAKYAPRFNG 810
           7******************************9******************************************************* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           ++qqD+qE+laflld+l+e+l++ ++kp+ e++++d   ++d+     a+e++ ++n+s+++dlF+gql+sq+kc++c+++s+r++p
   Q: 811  FQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSD--GRPDWevaaeAWENHLRRNRSIVVDLFHGQLRSQVKCKTCGHISVRFDP 895
           ********************************9999..6666666777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           f+ lslp+p+++ ++ e                                                                      
   Q: 896  FNFLSLPLPMDSYMHIEiivtkldgttpvryglrlnmdekytglkkhlsdlcalkpeqillaevhssniknfpqdnqkvrhstsssl 982
           **************999********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 983  cafeipipgsptstssspvqtefhngqpangvigglmngdlprstlipngmpntvvpcrmenglsnampnghalspsdspftgyiia 1069
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1070 vhrkmmrtemyflsaqknrpslfgmplivpctvhtrkrdlydavwiqvsrlasplppqeasnhaqdcddslgyqypftlrvvqkdgn 1156
           *************************************************************************************** PP
   S: 186  ....................................................................slqdcLesftkeeelegen 204
                                                                               +l++cL++ft eeel +++
   Q: 1157 scawcpwyrfchgckidcseerahmgnanlavdwdptalhlryqtsqeriaeehrsveqsrraqaepiNLDSCLRAFTGEEELGEDE 1243
           *************************************************************************************** PP
   S: 205  kyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts 267
           +yyc+kck ++ a+kkl+l++lP++Li+hLkRf+f +   + +k +k v+fp+e ++ s f+  
   Q: 1244 MYYCSKCKTHCLATKKLDLWRLPPILIIHLKRFQFVNG--RWIKSQKIVKFPREdFNPSAFLMP 1305
           *********************************99775..5569*********99*99998876 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MKGEAFTFVL CILTDLELKR LKDAFKRTCG LSCYMSQQCF IRDVLGDGVP PKVAEVIYCS 60
FGGTSKGLHF NNLIVGLVLL TRGRDEEKTK YIFSLFSNES GSYVVHEEME RMLLMVDGRV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAACTACTTC ACTAATATCA AAAGTATAAA ATGACAATAA CATACTCATT GTAATAAAAA 60
TTCCAAATTA GAAACAAAGC ATAAATTTAA ACATGACACT CAGTAAAAAC ATTATTGCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR029071--Ubiquitin-rel_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00972--USP_1
PS50235--USP_3

Pfam

PF06337--DUSP
PF13202--EF-hand_5
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP
SM00054--EFh

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005509--F:calcium ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001611	Ailuropoda melanoleuca	82.10	0.00e+00	1952.00
IUUC-Apl-003272	Anas platyrhynchos	83.77	0.00e+00	2324.00
IUUC-Ame-010781	Astyanax mexicanus	78.88	0.00e+00	2139.00
IUUC-Bta-013502	Bos taurus	79.68	0.00e+00	2159.00
IUUC-Cja-018754	Callithrix jacchus	83.31	0.00e+00	2360.00
IUUC-Cfa-020526	Canis familiaris	83.92	0.00e+00	2368.00
IUUC-Cpo-021568	Cavia porcellus	79.71	0.00e+00	2128.00
IUUC-Csa-023143	Chlorocebus sabaeus	84.10	0.00e+00	2329.00
IUUC-Cho-024603	Choloepus hoffmanni	52.89	2.00e-162	566.00
IUUC-Cin-025583	Ciona intestinalis	49.69	0.00e+00	1241.00
IUUC-Csv-026344	Ciona savignyi	46.85	0.00e+00	1148.00
IUUC-Dre-028121	Danio rerio	78.39	0.00e+00	2130.00
IUUC-Dno-029911	Dasypus novemcinctus	83.94	0.00e+00	2318.00
IUUC-Dor-030608	Dipodomys ordii	55.18	0.00e+00	961.00
IUUC-Dme-032094	Drosophila melanogaster	45.28	4.00e-124	439.00
IUUC-Ete-032639	Echinops telfairi	82.43	0.00e+00	1180.00
IUUC-Eca-034253	Equus caballus	84.61	0.00e+00	2349.00
IUUC-Eeu-035084	Erinaceus europaeus	76.18	0.00e+00	1440.00
IUUC-Fca-035474	Felis catus	82.69	0.00e+00	1862.00
IUUC-Fal-036985	Ficedula albicollis	84.09	0.00e+00	2322.00
IUUC-Gmo-039568	Gadus morhua	79.22	0.00e+00	2073.00
IUUC-Gga-040509	Gallus gallus	83.11	0.00e+00	2345.00
IUUC-Gac-041757	Gasterosteus aculeatus	78.87	0.00e+00	2129.00
IUUC-Ggo-044956	Gorilla gorilla	80.78	0.00e+00	1623.00
IUUC-Hsa-046107	Homo sapiens	84.25	0.00e+00	2353.00
IUUC-Itr-048865	Ictidomys tridecemlineatus	76.11	0.00e+00	663.00
IUUC-Lch-050681	Latimeria chalumnae	77.79	0.00e+00	2064.00
IUUC-Loc-052474	Lepisosteus oculatus	78.55	0.00e+00	2182.00
IUUC-Laf-054273	Loxodonta africana	84.12	0.00e+00	2353.00
IUUC-Mcc-054718	Macaca mulatta	84.40	0.00e+00	2358.00
IUUC-Meu-056558	Macropus eugenii	67.79	0.00e+00	1310.00
IUUC-Mga-059892	Meleagris gallopavo	84.96	0.00e+00	2313.00
IUUC-Mmr-060866	Microcebus murinus	82.80	0.00e+00	2355.00
IUUC-Mdo-062607	Monodelphis domestica	84.20	0.00e+00	2404.00
IUUC-Mmu-063797	Mus musculus	84.07	0.00e+00	2372.00
IUUC-Mpu-066121	Mustela putorius furo	83.99	0.00e+00	2385.00
IUUC-Mlu-067581	Myotis lucifugus	83.99	0.00e+00	2358.00
IUUC-Nle-069916	Nomascus leucogenys	81.95	0.00e+00	2272.00
IUUC-Opr-071073	Ochotona princeps	75.64	0.00e+00	1069.00
IUUC-Ont-071310	Oreochromis niloticus	79.60	0.00e+00	2098.00
IUUC-Oan-073356	Ornithorhynchus anatinus	83.32	0.00e+00	2366.00
IUUC-Ocu-074216	Oryctolagus cuniculus	84.21	0.00e+00	2364.00
IUUC-Ola-087434	Oryzias latipes	79.31	0.00e+00	2070.00
IUUC-Oga-089034	Otolemur garnettii	84.32	0.00e+00	2298.00
IUUC-Oar-090369	Ovis aries	84.63	0.00e+00	2360.00
IUUC-Ptr-090605	Pan troglodytes	84.33	0.00e+00	2357.00
IUUC-Pan-092381	Papio anubis	84.10	0.00e+00	2312.00
IUUC-Psi-093819	Pelodiscus sinensis	85.64	0.00e+00	2391.00
IUUC-Pma-094480	Petromyzon marinus	64.32	0.00e+00	1461.00
IUUC-Pfo-096561	Poecilia formosa	79.40	0.00e+00	2061.00
IUUC-Pab-097643	Pongo abelii	84.12	0.00e+00	2271.00
IUUC-Pca-100944	Procavia capensis	66.97	0.00e+00	879.00
IUUC-Pva-102732	Pteropus vampyrus	76.70	0.00e+00	2084.00
IUUC-Rno-105113	Rattus norvegicus	84.31	0.00e+00	2366.00
IUUC-Sar-113201	Sorex araneus	71.59	0.00e+00	1173.00
IUUC-Tgu-117322	Taeniopygia guttata	84.99	0.00e+00	2395.00
IUUC-Tru-118705	Takifugu rubripes	75.49	0.00e+00	668.00
IUUC-Tsy-119433	Tarsius syrichta	70.22	0.00e+00	1846.00
IUUC-Tni-120631	Tetraodon nigroviridis	79.03	0.00e+00	2080.00
IUUC-Tbe-127553	Tupaia belangeri	81.17	0.00e+00	649.00
IUUC-Ttr-128260	Tursiops truncatus	83.03	0.00e+00	2355.00
IUUC-Vpa-130479	Vicugna pacos	79.32	0.00e+00	2201.00
IUUC-Xtr-132686	Xenopus tropicalis	81.95	0.00e+00	2253.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence