iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004912

UUCD1 version

UUC-AnC-00856

Ensembl Protein ID

ENSACAP00000016907.2

UniProt Accession

G1KTL8; G1KTL8_ANOCA

Protein Name

Uncharacterized protein

Gene Name

KLHL3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000017120.2	ENSACAT00000017242.2	ENSACAP00000016907.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.00e-21	77.0	48	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	6.00e-11	41.4	147	178

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dv++v +++e++ah+ivLaa+S++F a+f++++ esk  +++eikdv+   ++ l++++Yt +++ +
   Q: 48   CDVVIVAEDVEIEAHRIVLAACSPYFCAMFTGDMTESK-AKKIEIKDVDGLTLSKLIDYIYTAEIEVT 114
           8*************************************.************************99876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           + Nclgi++fAd ++c++L ++a+ ++++hF+
   Q: 147  PTNCLGIRAFADVHTCSELLQQANAYAEQHFP 178
           78*****************************6 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MDDESIKGCP QPPEADGDKD QRTVTINSCH MGKAFKVMNE LRSKRLLCDV VIVAEDVEIE 60
AHRIVLAACS PYFCAMFTGD MTESKAKKIE IKDVDGLTLS KLIDYIYTAE IEVTEENVQV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGAGGCCCA CCGCTGTTGT TGCTAGGAGA CCGGAGTCGC CAGGAGGAGG AGCAGTAGCG 60
GCGGCCGCGG CAGAAGGGAG TGGGCCGCCG AGGCTGGAGG AGCAAAGGCA GGCGCAGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0072156--P:distal tubule morphogenesis
GO:0050801--P:ion homeostasis
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0070294--P:renal sodium ion absorption

KEGG

acs:100559916

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001632	Ailuropoda melanoleuca	94.20	0.00e+00	1124.00
IUUC-Apl-003965	Anas platyrhynchos	94.33	0.00e+00	1095.00
IUUC-Ate-010500	Aspergillus terreus	25.09	4.00e-20	92.40
IUUC-Ame-010670	Astyanax mexicanus	80.35	0.00e+00	937.00
IUUC-Bta-013354	Bos taurus	94.03	0.00e+00	1120.00
IUUC-Bol-016582	Brassica oleracea	30.00	5.00e-13	70.10
IUUC-Bra-017771	Brassica rapa	30.73	2.00e-13	71.20
IUUC-Cel-018136	Caenorhabditis elegans	42.26	6.00e-130	457.00
IUUC-Cja-019183	Callithrix jacchus	91.01	0.00e+00	996.00
IUUC-Cfa-020465	Canis familiaris	93.31	0.00e+00	1113.00
IUUC-Cpo-022115	Cavia porcellus	93.84	0.00e+00	1121.00
IUUC-Csa-024219	Chlorocebus sabaeus	93.53	0.00e+00	1123.00
IUUC-Csv-026032	Ciona savignyi	60.10	0.00e+00	696.00
IUUC-Cgl-026620	Colletotrichum gloeosporioides	29.97	9.00e-25	107.00
IUUC-Dre-028524	Danio rerio	74.84	0.00e+00	944.00
IUUC-Dno-029075	Dasypus novemcinctus	95.73	0.00e+00	1109.00
IUUC-Dor-030156	Dipodomys ordii	78.04	0.00e+00	906.00
IUUC-Ete-033064	Echinops telfairi	79.43	0.00e+00	823.00
IUUC-Eca-033887	Equus caballus	92.84	0.00e+00	1113.00
IUUC-Eeu-035244	Erinaceus europaeus	75.13	0.00e+00	884.00
IUUC-Fca-035375	Felis catus	93.86	0.00e+00	1121.00
IUUC-Fal-037119	Ficedula albicollis	96.22	0.00e+00	1069.00
IUUC-Fso-038219	Fusarium solani	38.71	5.00e-10	55.10
IUUC-Gga-041094	Gallus gallus	95.10	0.00e+00	1091.00
IUUC-Gac-042585	Gasterosteus aculeatus	76.25	0.00e+00	902.00
IUUC-Ggo-045485	Gorilla gorilla	93.05	0.00e+00	1114.00
IUUC-Hsa-046717	Homo sapiens	93.53	0.00e+00	1123.00
IUUC-Itr-048605	Ictidomys tridecemlineatus	94.79	0.00e+00	1121.00
IUUC-Lch-050246	Latimeria chalumnae	88.42	0.00e+00	996.00
IUUC-Laf-053700	Loxodonta africana	93.92	0.00e+00	1104.00
IUUC-Mcc-054732	Macaca mulatta	96.63	0.00e+00	998.00
IUUC-Mga-059994	Meleagris gallopavo	94.49	0.00e+00	984.00
IUUC-Mdo-062923	Monodelphis domestica	93.70	0.00e+00	1124.00
IUUC-Mmu-063842	Mus musculus	94.00	0.00e+00	1122.00
IUUC-Mpu-066380	Mustela putorius furo	94.38	0.00e+00	1133.00
IUUC-Mlu-067922	Myotis lucifugus	94.87	0.00e+00	1101.00
IUUC-Nle-069761	Nomascus leucogenys	93.53	0.00e+00	1122.00
IUUC-Opr-070287	Ochotona princeps	85.84	0.00e+00	1004.00
IUUC-Ont-071654	Oreochromis niloticus	78.66	0.00e+00	951.00
IUUC-Ocu-074957	Oryctolagus cuniculus	93.68	0.00e+00	1109.00
IUUC-Ome-081730	Oryza meridionalis	28.81	9.00e-11	62.40
IUUC-Ola-086853	Oryzias latipes	77.26	0.00e+00	903.00
IUUC-Oga-088559	Otolemur garnettii	93.04	0.00e+00	1115.00
IUUC-Oar-089925	Ovis aries	94.06	0.00e+00	1127.00
IUUC-Ptr-091487	Pan troglodytes	93.53	0.00e+00	1123.00
IUUC-Pan-091705	Papio anubis	93.53	0.00e+00	1123.00
IUUC-Psi-093478	Pelodiscus sinensis	92.43	0.00e+00	1045.00
IUUC-Pma-094177	Petromyzon marinus	72.92	0.00e+00	771.00
IUUC-Pfo-097450	Poecilia formosa	77.55	0.00e+00	886.00
IUUC-Pab-097618	Pongo abelii	93.36	0.00e+00	1120.00
IUUC-Pca-100739	Procavia capensis	86.93	0.00e+00	645.00
IUUC-Sha-106935	Sarcophilus harrisii	96.80	0.00e+00	742.00
IUUC-Ssc-115599	Sus scrofa	94.33	0.00e+00	1124.00
IUUC-Tgu-117001	Taeniopygia guttata	95.56	0.00e+00	1078.00
IUUC-Tru-118078	Takifugu rubripes	77.68	0.00e+00	939.00
IUUC-Tsy-119161	Tarsius syrichta	82.43	0.00e+00	852.00
IUUC-Tni-120888	Tetraodon nigroviridis	76.64	0.00e+00	876.00
IUUC-Tbe-127285	Tupaia belangeri	80.61	0.00e+00	641.00
IUUC-Ttr-128884	Tursiops truncatus	77.65	2.00e-142	499.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence