iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000010520.1	ENSLOCT00000012927.1	ENSLOCP00000012900.1
ENSLOCG00000010520.1	ENSLOCT00000012937.1	ENSLOCP00000012910.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.50e-12	44.9	737	789

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           k ++ly  +a++d eL++++G + + + + + + gWl+g  +legk Gl+Pen+ve
   Q: 737  KARALYACKAEHDSELSFTAGTIFENV-HPSREPGWLEG--TLEGKTGLIPENYVE 789
           7799***********************.***********..8*************8 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MGLPALEFSD CHLDSPQFRE RLKSHELELE KTNKFIKELI KDGKALIQAL KNLSSAKRKF 60
AESLNEFKFQ CIGDAETDDE ICIAKSLQEF AGVLKNLEDE RTRMIENASE VLITPLERFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAACAAGCA TGTGCTAACT GTTCCGAATA TGTCTACGCG ATTGGTTGCA ATGTTCGTCC 60
ATCATTAGAT TAAATGTTTC AGGGTAGGTT GGTGCGGACA CTGTAACAGC GCTGATGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0343--GTPase activation
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR030061--RHG26
IPR008936--Rho_GTPase_activation_prot
IPR000198--RhoGAP_dom
IPR001452--SH3_domain

PROSITE

PS50003--PH_DOMAIN
PS50238--RHOGAP
PS50002--SH3

Pfam

PF00169--PH
PF00620--RhoGAP
PF14604--SH3_9

SMART

SM00233--PH
SM00324--RhoGAP
SM00326--SH3

Gene Ontology

GO:0005096--F:GTPase activator activity
GO:0030036--P:actin cytoskeleton organization
GO:0051056--P:regulation of small GTPase mediated signal transduction
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001613	Ailuropoda melanoleuca	80.40	0.00e+00	1018.00
IUUC-Apl-003321	Anas platyrhynchos	81.52	0.00e+00	913.00
IUUC-Aca-004570	Anolis carolinensis	80.21	0.00e+00	1042.00
IUUC-Ame-011422	Astyanax mexicanus	79.39	0.00e+00	1043.00
IUUC-Bta-013262	Bos taurus	80.49	0.00e+00	937.00
IUUC-Cel-018542	Caenorhabditis elegans	44.26	1.00e-131	464.00
IUUC-Cja-019208	Callithrix jacchus	79.94	0.00e+00	1009.00
IUUC-Cfa-020928	Canis familiaris	80.58	0.00e+00	1019.00
IUUC-Cpo-021338	Cavia porcellus	80.09	0.00e+00	1017.00
IUUC-Csa-023570	Chlorocebus sabaeus	83.33	0.00e+00	1007.00
IUUC-Dno-029143	Dasypus novemcinctus	80.55	0.00e+00	1019.00
IUUC-Dor-030697	Dipodomys ordii	79.48	0.00e+00	1001.00
IUUC-Dme-032147	Drosophila melanogaster	41.01	2.00e-135	476.00
IUUC-Ete-032645	Echinops telfairi	73.97	0.00e+00	886.00
IUUC-Eca-033791	Equus caballus	80.37	0.00e+00	1013.00
IUUC-Eeu-035202	Erinaceus europaeus	60.34	2.00e-99	356.00
IUUC-Fca-036131	Felis catus	80.75	0.00e+00	994.00
IUUC-Fal-037129	Ficedula albicollis	75.40	0.00e+00	1119.00
IUUC-Gga-041023	Gallus gallus	81.76	0.00e+00	1049.00
IUUC-Ggo-044863	Gorilla gorilla	83.23	0.00e+00	1003.00
IUUC-Hsa-046471	Homo sapiens	83.66	0.00e+00	1009.00
IUUC-Itr-049060	Ictidomys tridecemlineatus	79.94	0.00e+00	1030.00
IUUC-Lch-050300	Latimeria chalumnae	79.93	0.00e+00	937.00
IUUC-Laf-053585	Loxodonta africana	80.27	0.00e+00	994.00
IUUC-Mcc-055458	Macaca mulatta	83.50	0.00e+00	1009.00
IUUC-Meu-056107	Macropus eugenii	68.04	0.00e+00	830.00
IUUC-Mga-059914	Meleagris gallopavo	78.43	0.00e+00	920.00
IUUC-Mmr-060728	Microcebus murinus	79.37	0.00e+00	919.00
IUUC-Mdo-062387	Monodelphis domestica	80.09	0.00e+00	1046.00
IUUC-Mmu-063756	Mus musculus	82.69	0.00e+00	1029.00
IUUC-Nle-069043	Nomascus leucogenys	77.45	0.00e+00	722.00
IUUC-Opr-071168	Ochotona princeps	69.04	0.00e+00	822.00
IUUC-Ont-072338	Oreochromis niloticus	79.46	0.00e+00	979.00
IUUC-Oan-073441	Ornithorhynchus anatinus	79.46	0.00e+00	848.00
IUUC-Ocu-073915	Oryctolagus cuniculus	82.85	0.00e+00	1026.00
IUUC-Ola-086319	Oryzias latipes	79.97	0.00e+00	1015.00
IUUC-Oar-089349	Ovis aries	80.91	0.00e+00	1019.00
IUUC-Ptr-091027	Pan troglodytes	83.50	0.00e+00	1006.00
IUUC-Pan-092791	Papio anubis	83.50	0.00e+00	1009.00
IUUC-Psi-093144	Pelodiscus sinensis	81.54	0.00e+00	1069.00
IUUC-Pab-097783	Pongo abelii	83.33	0.00e+00	1007.00
IUUC-Pva-102980	Pteropus vampyrus	81.03	0.00e+00	1050.00
IUUC-Rno-105142	Rattus norvegicus	79.64	0.00e+00	1044.00
IUUC-Sha-107213	Sarcophilus harrisii	79.58	0.00e+00	966.00
IUUC-Tru-117767	Takifugu rubripes	83.10	0.00e+00	1085.00
IUUC-Tsy-119150	Tarsius syrichta	76.95	0.00e+00	967.00
IUUC-Tni-119893	Tetraodon nigroviridis	81.90	0.00e+00	759.00
IUUC-Ttr-129028	Tursiops truncatus	68.09	0.00e+00	740.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence