iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000000757.3	ENSMMUT00000001088.3	ENSMMUP00000001020.2
ENSMMUG00000000757.3	ENSMMUT00000066481.1	ENSMMUP00000059618.1
ENSMMUG00000000757.3	ENSMMUT00000075039.1	ENSMMUP00000044982.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.00e-06	28.4	29	68
E3 activity/RING/U-box	4.80e-07	30.9	26	72

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle +++ p+ +pCgHvf+  Clq       ++ k+  C +Cr
   Q: 29   CPVCLEVYEK-PVQVPCGHVFCSACLQEC-----LKPKKPVCGVCR 68
           **********.999************555.....499999*****8 PP

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplt 51
            f Cp+ le+ + Pv +p+G+++  ++++++l+ ++  c v+r+ l+
   Q: 26   RFTCPVCLEVYEKPVQVPCGHVFCSACLQECLKPKKPVCGVCRSALA 72
           69*****************************************9986 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MAAQQQDGGG AAQLAGPAAE ADPLGRFTCP VCLEVYEKPV QVPCGHVFCS ACLQECLKPK 60
KPVCGVCRSA LAPGVRAMEL ERQIESTETS CHGCRKNFFL SKIRSHVATC SKYQNYIMEG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCGGCAGCA AGATGGCGGC GCAACAGCAA GACGGCGGGG GAGCTGCGCA GCTGGCGGGG 60
CCGGCGGCGG AGGCTGATCC CCTAGGCCGC TTCACGTGTC CCGTGTGCTT AGAGGTGTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008598--Di19_Zn_binding_dom
IPR034734--ZF_C2HC_RNF
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51803--ZF_C2HC_RNF
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF05605--zf-Di19
PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0005622--C:intracellular
GO:0005886--C:plasma membrane
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

KEGG

mcc:713517

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002315	Ailuropoda melanoleuca	94.74	3.00e-129	453.00
IUUC-Apl-004036	Anas platyrhynchos	76.80	1.00e-82	298.00
IUUC-Aca-004569	Anolis carolinensis	70.04	6.00e-97	346.00
IUUC-Bta-013345	Bos taurus	92.67	5.00e-126	443.00
IUUC-Cja-019919	Callithrix jacchus	96.05	3.00e-131	460.00
IUUC-Cfa-021164	Canis familiaris	94.74	2.00e-128	451.00
IUUC-Cpo-022051	Cavia porcellus	85.91	2.00e-114	404.00
IUUC-Csa-023956	Chlorocebus sabaeus	100.00	3.00e-124	436.00
IUUC-Dre-027499	Danio rerio	53.23	6.00e-66	243.00
IUUC-Dno-029437	Dasypus novemcinctus	94.35	3.00e-124	437.00
IUUC-Dor-030428	Dipodomys ordii	78.51	2.00e-103	367.00
IUUC-Ete-032855	Echinops telfairi	78.26	1.00e-94	338.00
IUUC-Eca-034236	Equus caballus	95.58	2.00e-102	364.00
IUUC-Eeu-034875	Erinaceus europaeus	95.74	2.00e-107	380.00
IUUC-Fca-036017	Felis catus	97.17	4.00e-123	433.00
IUUC-Fal-037133	Ficedula albicollis	75.69	6.00e-84	303.00
IUUC-Gga-040752	Gallus gallus	72.40	6.00e-97	346.00
IUUC-Ggo-044654	Gorilla gorilla	100.00	1.00e-77	281.00
IUUC-Hsa-046280	Homo sapiens	98.68	8.00e-126	442.00
IUUC-Itr-048594	Ictidomys tridecemlineatus	94.09	8.00e-103	365.00
IUUC-Lch-050028	Latimeria chalumnae	62.38	2.00e-79	288.00
IUUC-Loc-051797	Lepisosteus oculatus	59.41	5.00e-70	257.00
IUUC-Laf-054248	Loxodonta africana	95.03	1.00e-103	368.00
IUUC-Meu-056464	Macropus eugenii	58.56	2.00e-51	194.00
IUUC-Mga-059403	Meleagris gallopavo	73.57	2.00e-61	227.00
IUUC-Mmr-061582	Microcebus murinus	97.24	5.00e-105	373.00
IUUC-Mdo-062106	Monodelphis domestica	79.45	1.00e-100	358.00
IUUC-Mmu-064176	Mus musculus	89.43	3.00e-113	400.00
IUUC-Mpu-066083	Mustela putorius furo	95.61	3.00e-130	457.00
IUUC-Mlu-067060	Myotis lucifugus	93.72	5.00e-116	409.00
IUUC-Nle-069353	Nomascus leucogenys	99.03	8.00e-114	402.00
IUUC-Opr-070916	Ochotona princeps	89.04	2.00e-122	431.00
IUUC-Ont-072284	Oreochromis niloticus	56.73	1.00e-71	262.00
IUUC-Oan-072858	Ornithorhynchus anatinus	76.80	2.00e-82	297.00
IUUC-Ocu-074471	Oryctolagus cuniculus	93.86	2.00e-118	417.00
IUUC-Oin-079762	Oryza indica	52.17	4.00e-09	56.20
IUUC-Ola-087569	Oryzias latipes	53.85	1.00e-72	265.00
IUUC-Olu-087618	Ostreococcus lucimarinus	40.35	1.00e-07	50.40
IUUC-Oga-089164	Otolemur garnettii	96.21	1.00e-121	428.00
IUUC-Oar-089436	Ovis aries	93.81	7.00e-127	446.00
IUUC-Ptr-090945	Pan troglodytes	98.68	8.00e-126	442.00
IUUC-Pan-092765	Papio anubis	100.00	3.00e-124	436.00
IUUC-Psi-093593	Pelodiscus sinensis	75.35	3.00e-64	236.00
IUUC-Pma-094178	Petromyzon marinus	44.81	4.00e-44	170.00
IUUC-Pfo-096157	Poecilia formosa	54.72	1.00e-69	255.00
IUUC-Pab-098509	Pongo abelii	99.52	7.00e-125	439.00
IUUC-Pca-100293	Procavia capensis	90.10	5.00e-107	380.00
IUUC-Pva-102556	Pteropus vampyrus	92.11	3.00e-125	440.00
IUUC-Rno-105634	Rattus norvegicus	88.99	1.00e-111	395.00
IUUC-Sha-107052	Sarcophilus harrisii	77.88	4.00e-92	330.00
IUUC-Sja-107944	Schizosaccharomyces japonicus	36.76	4.00e-07	48.50
IUUC-Sar-113680	Sorex araneus	92.27	4.00e-91	326.00
IUUC-Ssc-115451	Sus scrofa	95.03	1.00e-103	367.00
IUUC-Tgu-116515	Taeniopygia guttata	75.41	2.00e-83	300.00
IUUC-Tru-117712	Takifugu rubripes	54.30	8.00e-72	263.00
IUUC-Tsy-119419	Tarsius syrichta	95.58	4.00e-103	366.00
IUUC-Tni-119774	Tetraodon nigroviridis	55.20	1.00e-71	262.00
IUUC-Tbe-127924	Tupaia belangeri	89.87	8.00e-116	409.00
IUUC-Ttr-128721	Tursiops truncatus	93.86	5.00e-129	452.00
IUUC-Vpa-130175	Vicugna pacos	70.72	5.00e-85	306.00
IUUC-Xtr-131851	Xenopus tropicalis	57.77	5.00e-73	266.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence