iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093849

Ensembl Protein ID

ENSPSIP00000005510.1

UniProt Accession

K7FBV0; K7FBV0_PELSI

Genbank Protein ID

ENSPSIP00000005510

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01170612

Gene Name

USP15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000005087.1	ENSPSIT00000005543.1	ENSPSIP00000005510.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.50e-118	395.2	290	935
ULD/UDP/UBQ/UBQ_Other	8.30e-09	35.2	154	220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS++QcLsn+p+l+e++l+ k++ +ln +np ++ ge++ks+++l++++w++k ++v+pr+++++++++a++fsgy+
   Q: 290  CGLSNLGNTCFMNSAIQCLSNTPPLTEYFLNdKYQDELNFDNPLGMRGEIAKSYADLIKQMWSGKYSYVTPRAFKTQVGRFAPQFSGYQ 378
           7******************************9********************************************************* PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqD+qE+laflld+l+e+l++ ++kp+ ++++++   ++d+     a+e++ k+n+s+i+d+F+g +ks+++c++c+++s++++pf++l
   Q: 379  QQDCQELLAFLLDGLHEDLNRIRKKPYIQLKDAE--GRPDKvvaeeAWENHLKRNDSIIVDIFHGLFKSTLVCPKCAKISVTFDPFCYL 465
           ****************************998887..5555556777******************************************* PP
   S: 173  slpvpgkeetkke............................................................................ 185
           +lp+p+++e+ +e                                                                            
   Q: 466  TLPLPMRKERTLEvylvrmdplnkpmqykvvvpkignildlctalstlsgvaadkmivtdiynhrfhrifamdenlssimerddiyvfe 554
           ********99999**************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 555  ialnrtedteqvvipvclrekyrhtsyshhsgsslfgqpflitvprnntedklynllllrmcryvktctesedtegslhcckdhgingn 643
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 644  gpngiheegspsemetdeqddessqdqelpsenensqsedsvggdndsengicteetckgqlltghkkrlftfqfnnlgstdinyikdd 732
           ***************************************************************************************** PP
   S: 186  ........................................................slqdcLesftkeeelegenkyycekckkkqeae 218
                                                                   +l+dc+e ft++e+l  e+ +yc++ck++q+a+
   Q: 733  trhirfddrqlrldersflaldwdpemkkryfddnaaedfekhesveykppkkpfvKLKDCIELFTTKEKLGVEDPWYCPTCKEHQQAT 821
           ***************************************************************************************** PP
   S: 219  kklklkklPevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk. 305
           kkl+l++lP+vL++hLkRfs+s+  ++r k+++ v+fp++ Ld+s+f+++p+ +   +++Y+Liav +H+G++++GHY+a++kn++++ 
   Q: 822  KKLDLWSLPPVLVVHLKRFSYSR--YMRDKLDTLVDFPINdLDMSEFLINPNAG---PCRYNLIAVSNHYGGMGGGHYTAFAKNKDDGk 905
           *******************9977..6999*********************9988...8**************************65555 PP
   S: 306  WllfdDskVtevkeeevleetgstaYvlfYkrr 338
           W++fdDs+V++ +e+++++   + aYvlfY+r+
   Q: 906  WYYFDDSSVSTASEDQIVS---KAAYVLFYQRQ 935
           *******************...*********96 PP

ULD/UDP/UBQ/UBQ_Other

   S: 16   kvnpsdtVaeLKekiekklgip.peqqrLiyk.....GkiL.eddktLadyglkdgstihllekksg 75
           +++++dt+ ++ ++i+k ++ip +++ rL++k      ++L ++d t++d gl++g+++++++k+++
   Q: 154  RFSKADTIDTIEKEIRKIFNIPnERETRLWNKymsntFEPLnKPDSTIQDAGLYQGQVLVIEQKNED 220
           4899******************999*****998875544569*********************9986 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MHMQLFYFIL YQYGSTKTVL LFLSVIIYFP FSRYLVDSRW FKQWKKYVGF DSWDKYQMGD 60
QNVYPGPIDN SGLLKDGDSQ SLKEHLIDEL DYILLPTEGW NKLVSWYTLM ESQEPIARKV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGGACCAAC CGGCAGCGCC CCAGCTGCTG TACCACAGGC GTCCGGAGCA AAGCCGTGGA 60
GCACGGGGGC AGCGGGACAG CCCAGACGCG TTGAAGACCA GCTGGTTCCA GGAAGCCCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR013792--RNA3'P_cycl/enolpyr_Trfase_a/b
IPR028135--Ub_USP-typ
IPR029071--Ubiquitin-rel_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH
PF14533--USP7_C2

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0030509--P:BMP signaling pathway
GO:0035616--P:histone H2B conserved C-terminal lysine deubiquitination
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0060389--P:pathway-restricted SMAD protein phosphorylation
GO:0007179--P:transforming growth factor beta receptor signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001852	Ailuropoda melanoleuca	92.98	0.00e+00	1759.00
IUUC-Apl-003249	Anas platyrhynchos	96.74	0.00e+00	1737.00
IUUC-Aca-004261	Anolis carolinensis	94.54	0.00e+00	1689.00
IUUC-Acl-008284	Aspergillus clavatus	36.91	9.00e-56	212.00
IUUC-Afl-008507	Aspergillus flavus	39.30	5.00e-54	206.00
IUUC-Afu-008878	Aspergillus fumigatus	37.53	3.00e-55	211.00
IUUC-Ani-009479	Aspergillus nidulans	42.81	1.00e-51	199.00
IUUC-Ang-009562	Aspergillus niger	36.14	8.00e-56	213.00
IUUC-Aor-009949	Aspergillus oryzae	38.50	3.00e-53	203.00
IUUC-Ate-010323	Aspergillus terreus	36.43	7.00e-54	206.00
IUUC-Ame-010757	Astyanax mexicanus	78.89	0.00e+00	1273.00
IUUC-Bgr-012277	Blumeria graminis	43.66	3.00e-63	237.00
IUUC-Bta-013128	Bos taurus	91.81	0.00e+00	1736.00
IUUC-Bci-013993	Botrytis cinerea	43.30	1.00e-64	241.00
IUUC-Bdi-014013	Brachypodium distachyon	36.66	1.00e-148	520.00
IUUC-Bol-015570	Brassica oleracea	37.61	4.00e-150	525.00
IUUC-Bra-017029	Brassica rapa	36.38	1.00e-135	477.00
IUUC-Cja-019222	Callithrix jacchus	93.07	0.00e+00	1763.00
IUUC-Cfa-020035	Canis familiaris	93.08	0.00e+00	1760.00
IUUC-Cpo-022071	Cavia porcellus	93.27	0.00e+00	1683.00
IUUC-Csa-023882	Chlorocebus sabaeus	93.39	0.00e+00	1766.00
IUUC-Cin-025292	Ciona intestinalis	44.81	0.00e+00	719.00
IUUC-Csv-026109	Ciona savignyi	47.70	9.00e-150	524.00
IUUC-Cgl-026741	Colletotrichum gloeosporioides	35.56	2.00e-60	228.00
IUUC-Cne-026852	Cryptococcus neoformans	39.07	2.00e-71	265.00
IUUC-Cme-027338	Cyanidioschyzon merolae	55.91	5.00e-68	252.00
IUUC-Dre-027869	Danio rerio	59.04	0.00e+00	1059.00
IUUC-Dno-029025	Dasypus novemcinctus	90.46	0.00e+00	1703.00
IUUC-Dor-030956	Dipodomys ordii	84.96	0.00e+00	1556.00
IUUC-Eca-034340	Equus caballus	93.39	0.00e+00	1765.00
IUUC-Eeu-034488	Erinaceus europaeus	83.12	0.00e+00	1148.00
IUUC-Fca-035552	Felis catus	91.39	0.00e+00	1723.00
IUUC-Fal-036618	Ficedula albicollis	96.54	0.00e+00	1731.00
IUUC-Fox-037986	Fusarium oxysporum	42.31	5.00e-62	233.00
IUUC-Fso-038291	Fusarium solani	30.10	6.00e-65	243.00
IUUC-Gga-041146	Gallus gallus	95.48	0.00e+00	1717.00
IUUC-Gac-041679	Gasterosteus aculeatus	77.83	0.00e+00	1423.00
IUUC-Gma-043077	Glycine max	36.76	1.00e-152	533.00
IUUC-Ggo-045002	Gorilla gorilla	93.19	0.00e+00	1761.00
IUUC-Hsa-046052	Homo sapiens	93.28	0.00e+00	1764.00
IUUC-Hvu-047108	Hordeum vulgare	40.18	8.00e-124	437.00
IUUC-Itr-048306	Ictidomys tridecemlineatus	91.72	0.00e+00	1731.00
IUUC-Kpa-049332	Komagataella pastoris	33.39	2.00e-67	250.00
IUUC-Lch-050107	Latimeria chalumnae	86.78	0.00e+00	1713.00
IUUC-Lpe-051185	Leersia perrieri	39.91	3.00e-124	439.00
IUUC-Loc-052105	Lepisosteus oculatus	83.07	0.00e+00	1463.00
IUUC-Lma-052981	Leptosphaeria maculans	33.91	8.00e-65	243.00
IUUC-Laf-053645	Loxodonta africana	92.66	0.00e+00	1754.00
IUUC-Mcc-055586	Macaca mulatta	93.28	0.00e+00	1764.00
IUUC-Meu-056764	Macropus eugenii	88.62	0.00e+00	1003.00
IUUC-Mor-056985	Magnaporthe oryzae	42.70	7.00e-60	226.00
IUUC-Mpo-057486	Magnaporthe poae	43.43	1.00e-60	228.00
IUUC-Mtr-058138	Medicago truncatula	37.23	9.00e-157	547.00
IUUC-Mla-058848	Melampsora laricipopulina	38.84	6.00e-66	246.00
IUUC-Mga-060162	Meleagris gallopavo	95.80	0.00e+00	1721.00
IUUC-Mvi-060324	Microbotryum violaceum	39.27	1.00e-72	268.00
IUUC-Mmr-061105	Microcebus murinus	93.60	0.00e+00	1768.00
IUUC-Mdo-062107	Monodelphis domestica	94.12	0.00e+00	1764.00
IUUC-Mmu-063662	Mus musculus	92.03	0.00e+00	1744.00
IUUC-Mac-064956	Musa acuminata	38.14	2.00e-107	383.00
IUUC-Mpu-065868	Mustela putorius furo	91.06	0.00e+00	1749.00
IUUC-Mlu-068000	Myotis lucifugus	87.27	0.00e+00	1625.00
IUUC-Nfi-068330	Neosartorya fischeri	36.75	4.00e-55	210.00
IUUC-Ncr-068879	Neurospora crassa	45.62	1.00e-60	228.00
IUUC-Nle-069874	Nomascus leucogenys	93.70	0.00e+00	1748.00
IUUC-Opr-071212	Ochotona princeps	87.88	0.00e+00	1653.00
IUUC-Ont-071834	Oreochromis niloticus	78.59	0.00e+00	1400.00
IUUC-Ocu-074573	Oryctolagus cuniculus	93.49	0.00e+00	1770.00
IUUC-Oba-075553	Oryza barthii	39.94	4.00e-127	448.00
IUUC-Ogl-077583	Oryza glaberrima	39.94	4.00e-127	448.00
IUUC-Oin-079300	Oryza indica	40.09	3.00e-128	452.00
IUUC-Opu-083770	Oryza punctata	39.94	2.00e-126	446.00
IUUC-Osa-085641	Oryza sativa	40.09	3.00e-128	452.00
IUUC-Oga-089022	Otolemur garnettii	91.28	0.00e+00	1726.00
IUUC-Oar-089767	Ovis aries	93.28	0.00e+00	1764.00
IUUC-Ptr-091319	Pan troglodytes	91.91	0.00e+00	1740.00
IUUC-Pan-091968	Papio anubis	93.39	0.00e+00	1766.00
IUUC-Pma-094533	Petromyzon marinus	59.49	0.00e+00	1059.00
IUUC-Pno-094890	Phaeosphaeria nodorum	35.15	6.00e-57	216.00
IUUC-Pfo-097110	Poecilia formosa	77.36	0.00e+00	1401.00
IUUC-Pab-098664	Pongo abelii	93.39	0.00e+00	1766.00
IUUC-Pca-100359	Procavia capensis	75.67	0.00e+00	1273.00
IUUC-Ppe-101587	Prunus persica	37.93	6.00e-151	528.00
IUUC-Pva-102394	Pteropus vampyrus	91.71	0.00e+00	1724.00
IUUC-Pgr-103546	Puccinia graminis	29.66	2.00e-66	248.00
IUUC-Ptt-103847	Puccinia triticina	38.79	9.00e-61	229.00
IUUC-Pte-104102	Pyrenophora teres	32.90	4.00e-56	214.00
IUUC-Pyt-104812	Pyrenophora triticirepentis	39.56	7.00e-55	209.00
IUUC-Rno-105383	Rattus norvegicus	90.97	0.00e+00	1723.00
IUUC-Sce-106170	Saccharomyces cerevisiae	37.30	3.00e-61	230.00
IUUC-Sha-107393	Sarcophilus harrisii	94.12	0.00e+00	1768.00
IUUC-Sja-107752	Schizosaccharomyces japonicus	35.60	3.00e-81	296.00
IUUC-Ssl-108461	Sclerotinia sclerotiorum	30.77	6.00e-13	69.30
IUUC-Smo-108686	Selaginella moellendorffii	45.95	4.00e-78	285.00
IUUC-Sit-109948	Setaria italica	36.41	4.00e-137	481.00
IUUC-Sly-111726	Solanum lycopersicum	40.53	6.00e-91	328.00
IUUC-Sar-113498	Sorex araneus	93.07	0.00e+00	1761.00
IUUC-Sre-115130	Sporisorium reilianum	42.74	4.00e-76	280.00
IUUC-Ssc-115285	Sus scrofa	93.50	0.00e+00	1766.00
IUUC-Tgu-116529	Taeniopygia guttata	96.43	0.00e+00	1735.00
IUUC-Tru-118298	Takifugu rubripes	78.11	0.00e+00	1406.00
IUUC-Tsy-119117	Tarsius syrichta	84.96	0.00e+00	1105.00
IUUC-Tni-120093	Tetraodon nigroviridis	75.25	0.00e+00	1349.00
IUUC-Tca-121001	Theobroma cacao	35.35	1.00e-150	526.00
IUUC-Tre-121888	Trichoderma reesei	42.29	2.00e-61	231.00
IUUC-Tvi-122422	Trichoderma virens	40.14	3.00e-56	214.00
IUUC-Tme-127062	Tuber melanosporum	34.14	5.00e-76	279.00
IUUC-Tbe-127672	Tupaia belangeri	91.14	0.00e+00	1162.00
IUUC-Uma-129498	Ustilago maydis	39.43	2.00e-70	261.00
IUUC-Vda-129781	Verticillium dahliae	37.43	9.00e-65	242.00
IUUC-Vpa-130469	Vicugna pacos	92.97	0.00e+00	1748.00
IUUC-Xtr-132729	Xenopus tropicalis	82.13	0.00e+00	1572.00
IUUC-Xma-133550	Xiphophorus maculatus	77.36	0.00e+00	1397.00
IUUC-Yli-134392	Yarrowia lipolytica	38.46	3.00e-62	234.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence