iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098325

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01118593

Gene Name

HECTD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000001420.2	ENSPPYT00000001701.2	ENSPPYP00000001645.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.60e-31	109.3	526	665

Active Site

Position(s)	Description	Evidence
684	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 8    rlevefvgEegldlgGvtreflallskelqnpd......lglflysendketlqpnpdsglknp..ehlklFeflGrllgkalqdgrll 88
            +e++f  E  +d+gG +r+ la +s+el+ ++      l++f++++n+ + +  ++d+++ np  + +  +e++G+l+g al+ +++l
   Q: 526  WWECKFIAEGIIDQGGGFRDSLADMSEELCPSSadtpvpLPFFVRTANQGNGTGEARDMYVPNPscQDFAKYEWIGQLMGAALRGKEFL 614
           355*****************************9999*99**********************99999999******************** PP
   S: 89   dlplsksfyklllgkklsl.edleevdpelykslkeikenaesdieelgldltfsv 143
            l l+ +++k+l g+++s+ +d+++vd+ l+k l+ ++ +     ++++++++f +
   Q: 615  VLALPGFVWKQLSGEEVSWsKDFPAVDSVLVKLLEVMEGM-----DKETFEFKFGK 665
           **************************************55.....56666776653 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MAGPGPGAVL ETPRQLLGRV RFLAEAARSL RAGRPLPAAL AFVPREVLYK LYKDPAGPSR 60
VLLPVWEAEG VGLRVGAAGP APGTGSGPLR AARDSIELRR GACVRTTGEE LCNGHGLWVK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGATTCGC TGGGAGTGGG AGGAAAAAGA GCAGGCCGAA GAACCAGAAA AATGACTGTT 60
GGCAATGATC CAGGCTAGCT AGAATGGTGA CTTGAATGAG GGTAGTAGCA GTAGAGATAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR004939--APC_su10/DOC_dom
IPR008979--Galactose-bd-like
IPR000569--HECT_dom

PROSITE

PS51284--DOC
PS50237--HECT

Pfam

PF03256--ANAPC10
PF00632--HECT

SMART

SM01337--APC10

Gene Ontology

GO:0048471--C:perinuclear region of cytoplasm
GO:0004842--F:ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process

KEGG

pon:100432333

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001229	Ailuropoda melanoleuca	97.47	0.00e+00	1290.00
IUUC-Apl-003715	Anas platyrhynchos	83.82	0.00e+00	966.00
IUUC-Aca-004377	Anolis carolinensis	75.96	0.00e+00	1038.00
IUUC-Ame-011918	Astyanax mexicanus	61.86	0.00e+00	838.00
IUUC-Bta-012736	Bos taurus	98.07	0.00e+00	1304.00
IUUC-Cja-019926	Callithrix jacchus	98.21	0.00e+00	1296.00
IUUC-Cfa-020753	Canis familiaris	98.71	0.00e+00	797.00
IUUC-Cpo-021415	Cavia porcellus	97.17	0.00e+00	1284.00
IUUC-Csa-023096	Chlorocebus sabaeus	99.26	0.00e+00	1305.00
IUUC-Dre-028746	Danio rerio	65.96	0.00e+00	877.00
IUUC-Dno-029293	Dasypus novemcinctus	97.66	0.00e+00	695.00
IUUC-Dor-031113	Dipodomys ordii	98.57	0.00e+00	862.00
IUUC-Ete-032601	Echinops telfairi	88.60	0.00e+00	1065.00
IUUC-Eca-034198	Equus caballus	94.64	0.00e+00	1255.00
IUUC-Eeu-034708	Erinaceus europaeus	97.68	7.00e-152	531.00
IUUC-Fca-035478	Felis catus	98.28	0.00e+00	1268.00
IUUC-Fal-037366	Ficedula albicollis	73.91	0.00e+00	994.00
IUUC-Gmo-039020	Gadus morhua	73.35	0.00e+00	755.00
IUUC-Gga-040332	Gallus gallus	76.81	0.00e+00	1054.00
IUUC-Gac-042336	Gasterosteus aculeatus	66.77	0.00e+00	926.00
IUUC-Ggo-045382	Gorilla gorilla	99.40	0.00e+00	1308.00
IUUC-Hsa-046562	Homo sapiens	99.40	0.00e+00	1308.00
IUUC-Itr-048208	Ictidomys tridecemlineatus	98.07	0.00e+00	1296.00
IUUC-Lch-049606	Latimeria chalumnae	64.38	0.00e+00	701.00
IUUC-Loc-052448	Lepisosteus oculatus	67.48	0.00e+00	797.00
IUUC-Laf-054507	Loxodonta africana	97.02	0.00e+00	1321.00
IUUC-Mcc-055690	Macaca mulatta	99.26	0.00e+00	1306.00
IUUC-Meu-055970	Macropus eugenii	82.59	0.00e+00	1078.00
IUUC-Mga-059654	Meleagris gallopavo	83.89	0.00e+00	955.00
IUUC-Mmr-061069	Microcebus murinus	98.51	0.00e+00	1300.00
IUUC-Mdo-062547	Monodelphis domestica	83.33	1.00e-123	436.00
IUUC-Mmu-063096	Mus musculus	97.47	0.00e+00	1293.00
IUUC-Mpu-065846	Mustela putorius furo	97.32	0.00e+00	1298.00
IUUC-Mlu-067992	Myotis lucifugus	96.78	0.00e+00	1191.00
IUUC-Nle-069565	Nomascus leucogenys	99.40	0.00e+00	1307.00
IUUC-Opr-070853	Ochotona princeps	87.59	0.00e+00	744.00
IUUC-Ont-071628	Oreochromis niloticus	66.07	0.00e+00	893.00
IUUC-Ocu-074094	Oryctolagus cuniculus	98.51	0.00e+00	1299.00
IUUC-Ola-087384	Oryzias latipes	65.84	0.00e+00	935.00
IUUC-Oga-088224	Otolemur garnettii	97.75	0.00e+00	1294.00
IUUC-Oar-090043	Ovis aries	91.07	0.00e+00	1202.00
IUUC-Ptr-090852	Pan troglodytes	99.26	0.00e+00	1302.00
IUUC-Pan-092787	Papio anubis	99.26	0.00e+00	1308.00
IUUC-Psi-092986	Pelodiscus sinensis	71.63	0.00e+00	700.00
IUUC-Pma-094416	Petromyzon marinus	37.46	6.00e-119	421.00
IUUC-Pfo-096720	Poecilia formosa	67.26	0.00e+00	938.00
IUUC-Pca-100885	Procavia capensis	87.68	0.00e+00	851.00
IUUC-Pva-102829	Pteropus vampyrus	85.74	0.00e+00	1043.00
IUUC-Rno-104882	Rattus norvegicus	97.62	0.00e+00	1291.00
IUUC-Sha-106811	Sarcophilus harrisii	91.04	1.00e-115	409.00
IUUC-Sar-113020	Sorex araneus	78.42	4.00e-145	508.00
IUUC-Ssc-115436	Sus scrofa	98.52	1.00e-158	552.00
IUUC-Tgu-117042	Taeniopygia guttata	76.58	0.00e+00	1043.00
IUUC-Tru-118419	Takifugu rubripes	61.10	0.00e+00	845.00
IUUC-Tsy-118829	Tarsius syrichta	97.73	0.00e+00	984.00
IUUC-Tni-120410	Tetraodon nigroviridis	61.65	0.00e+00	743.00
IUUC-Tbe-128113	Tupaia belangeri	95.41	7.00e-176	610.00
IUUC-Ttr-128167	Tursiops truncatus	97.62	0.00e+00	1325.00
IUUC-Xtr-132910	Xenopus tropicalis	59.82	0.00e+00	783.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence