iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	89.17	0.00e+00	2341.00	IUUC-Hsa-046753
E3 activity/N-recognin/UBR-box	89.17	0.00e+00	2341.00	IUUC-Hsa-046753
E3 activity/N-recognin/N-domain	89.17	0.00e+00	2341.00	IUUC-Hsa-046753
E3 activity/RING/RING	93.53	0.00e+00	2452.00	IUUC-Mmu-063389
E3 activity/N-recognin/UBR-box	93.53	0.00e+00	2452.00	IUUC-Mmu-063389
E3 activity/N-recognin/N-domain	93.53	0.00e+00	2452.00	IUUC-Mmu-063389

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

ARHLIEEQNV ISVITETLLE VLPEYLDRNN KFNFQGYSQD KLGRVYAVIC DLKYILISKP 60
LVWTERLRAQ FLEGFRSFLK ILTCMQGMEE IRRQVGQHIE VDPDWEAAIA IQMQLKNILL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCGACATC TTATTGAAGA GCAGAATGTT ATTTCTGTCA TTACTGAAAC TCTGCTGGAA 60
GTTCTACCTG AGTACTTGGA CAGGAACAAT AAGTTCAACT TCCAGGGCTA TAGCCAGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR011991--WHTH_DNA-bd_dom
IPR013083--Znf_RING/FYVE/PHD

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000502--C:proteasome complex
GO:0000151--C:ubiquitin ligase complex
GO:0070728--F:leucine binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0071233--P:cellular response to leucine
GO:0032007--P:negative regulation of TOR signaling
GO:0071596--P:ubiquitin-dependent protein catabolic process via the N-end rule pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001354	Ailuropoda melanoleuca	87.97	0.00e+00	2328.00
IUUC-Apl-004160	Anas platyrhynchos	74.89	0.00e+00	1988.00
IUUC-Aca-004982	Anolis carolinensis	71.46	0.00e+00	1881.00
IUUC-Ate-010550	Aspergillus terreus	22.78	4.00e-33	138.00
IUUC-Bta-012347	Bos taurus	88.65	0.00e+00	2365.00
IUUC-Cja-018911	Callithrix jacchus	84.64	0.00e+00	2216.00
IUUC-Cfa-020991	Canis familiaris	89.47	0.00e+00	2367.00
IUUC-Cpo-021448	Cavia porcellus	86.11	0.00e+00	2303.00
IUUC-Csa-024255	Chlorocebus sabaeus	88.44	0.00e+00	1779.00
IUUC-Cho-024550	Choloepus hoffmanni	71.95	0.00e+00	1823.00
IUUC-Csv-026296	Ciona savignyi	29.72	1.00e-18	87.00
IUUC-Dno-029427	Dasypus novemcinctus	87.61	0.00e+00	2300.00
IUUC-Dor-031073	Dipodomys ordii	83.57	0.00e+00	976.00
IUUC-Ete-032318	Echinops telfairi	71.40	2.00e-173	603.00
IUUC-Eca-033348	Equus caballus	88.81	0.00e+00	2374.00
IUUC-Eeu-034664	Erinaceus europaeus	79.26	0.00e+00	2087.00
IUUC-Fca-035604	Felis catus	85.42	0.00e+00	1405.00
IUUC-Fal-037333	Ficedula albicollis	74.36	0.00e+00	1975.00
IUUC-Gmo-039363	Gadus morhua	54.90	0.00e+00	1347.00
IUUC-Gga-040486	Gallus gallus	73.76	0.00e+00	1904.00
IUUC-Gac-041985	Gasterosteus aculeatus	54.50	0.00e+00	1384.00
IUUC-Ggo-044704	Gorilla gorilla	79.28	0.00e+00	1650.00
IUUC-Hsa-046753	Homo sapiens	89.17	0.00e+00	2355.00
IUUC-Itr-048410	Ictidomys tridecemlineatus	88.87	0.00e+00	2340.00
IUUC-Loc-052624	Lepisosteus oculatus	59.71	0.00e+00	1534.00
IUUC-Laf-053857	Loxodonta africana	84.53	0.00e+00	2247.00
IUUC-Mcc-054873	Macaca mulatta	88.65	0.00e+00	2304.00
IUUC-Meu-056858	Macropus eugenii	58.32	0.00e+00	824.00
IUUC-Mga-059917	Meleagris gallopavo	75.04	0.00e+00	2016.00
IUUC-Mmr-061128	Microcebus murinus	83.68	0.00e+00	2154.00
IUUC-Mdo-062306	Monodelphis domestica	76.62	0.00e+00	2097.00
IUUC-Mmu-063389	Mus musculus	93.53	0.00e+00	2473.00
IUUC-Mpu-065983	Mustela putorius furo	88.95	0.00e+00	2374.00
IUUC-Mlu-068013	Myotis lucifugus	86.93	0.00e+00	2315.00
IUUC-Nle-070031	Nomascus leucogenys	89.47	0.00e+00	2366.00
IUUC-Opr-070551	Ochotona princeps	75.17	0.00e+00	794.00
IUUC-Ocu-074930	Oryctolagus cuniculus	82.50	0.00e+00	2169.00
IUUC-Oba-075295	Oryza barthii	39.58	2.00e-14	76.30
IUUC-Ogl-077571	Oryza glaberrima	38.96	5.00e-20	94.40
IUUC-Ogu-078497	Oryza glumaepatula	39.58	2.00e-14	76.30
IUUC-Oin-079343	Oryza indica	39.58	2.00e-14	75.90
IUUC-Oni-083099	Oryza nivara	39.58	2.00e-14	75.90
IUUC-Oru-084471	Oryza rufipogon	39.58	2.00e-14	75.90
IUUC-Osa-085336	Oryza sativa	38.96	4.00e-20	93.60
IUUC-Oga-088017	Otolemur garnettii	84.56	0.00e+00	2206.00
IUUC-Oar-089557	Ovis aries	87.72	0.00e+00	2349.00
IUUC-Ptr-091366	Pan troglodytes	87.59	0.00e+00	2323.00
IUUC-Pan-092184	Papio anubis	88.65	0.00e+00	2304.00
IUUC-Psi-093720	Pelodiscus sinensis	74.74	0.00e+00	1924.00
IUUC-Pab-098586	Pongo abelii	89.25	0.00e+00	2355.00
IUUC-Pca-100673	Procavia capensis	83.57	0.00e+00	984.00
IUUC-Pva-102724	Pteropus vampyrus	80.83	0.00e+00	2088.00
IUUC-Sha-106993	Sarcophilus harrisii	77.67	0.00e+00	2098.00
IUUC-Sar-113447	Sorex araneus	87.68	0.00e+00	1414.00
IUUC-Ssc-115768	Sus scrofa	88.38	0.00e+00	2369.00
IUUC-Tgu-116949	Taeniopygia guttata	68.07	0.00e+00	1763.00
IUUC-Tsy-119177	Tarsius syrichta	77.44	0.00e+00	1981.00
IUUC-Tbe-128088	Tupaia belangeri	75.19	0.00e+00	1143.00
IUUC-Ttr-129062	Tursiops truncatus	81.67	0.00e+00	2113.00
IUUC-Vpa-130578	Vicugna pacos	80.90	0.00e+00	2105.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence