iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117782

UUCD1 version

UUC-TaR-00174

Ensembl Protein ID

ENSTRUP00000009297.1

UniProt Accession

H2SA71; H2SA71_TAKRU

Protein Name

Uncharacterized protein

Gene Name

UBR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000003934.1	ENSTRUT00000009352.1	ENSTRUP00000009297.1
ENSTRUG00000003934.1	ENSTRUT00000009353.1	ENSTRUP00000009298.1
ENSTRUG00000003934.1	ENSTRUT00000009354.1	ENSTRUP00000009299.1
ENSTRUG00000003934.1	ENSTRUT00000009355.1	ENSTRUP00000009300.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.10e-07	30.5	1088	1194
E3 activity/N-recognin/UBR-box	1.40e-28	100.4	93	162

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf....kd...........................................gplvlpCgHvfhadClqkw........... 29
           C++C+e+     k                                            g+++++CgHv+ha+C+qk+           
   Q: 1088 CILCQEEQevgaKAqamvltacvqrstvltqcrgkipvssadgvgpyplfmspylalGTHTGSCGHVMHATCWQKYfeavqntsrnr 1174
           8888776644440033444444444555555555555555555655555555555556899***************88877777777 PP
   S: 30   ...pglknssskefrCPlCr 46
                  +++++e +CPlC+
   Q: 1175 lhaEMIIDLENGEYLCPLCK 1194
           777555556777777****6 PP

E3 activity/N-recognin/UBR-box

   S: 1    slCgrvfkvgetiyeCrtCsvdetlvlCteCfakvvHkdHeyklkksggggfCdCGdteAwedgskCkkl 70
           +lCgrvfk get+y+Cr+C++d+t+v+C++Cf+ +vHk+H+yk++ s+gggfCdCGd eAw+ g++C k+
   Q: 93   QLCGRVFKEGETVYSCRDCAIDPTCVMCMDCFQGSVHKGHRYKMHPSSGGGFCDCGDVEAWKIGPYCSKH 162
           68*****************************************************************998 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

LCTHIPPGIT AIIPKQVVFA VQEWLEAADI RVELLQYLKE QVPQNFCLKT EPSPEEEDEF 60
MQVDLLHPLE CFLFGEDPRE GLEKLKQGCS SPQLCGRVFK EGETVYSCRD CAIDPTCVMC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGTGTACTC ACATCCCCCC AGGTTAGGTC TGATGGCCAG CCTGGGGAAG AGTCTTGCTT 60
ATGCCAAACT TTTATTTTAA TGGTTTTGAC CTCATGCTTG GCTTCTACTC TGATTGGTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003769--ClpS_core
IPR014719--Ribosomal_L7/12_C/ClpS-like
IPR011991--WHTH_DNA-bd_dom
IPR013083--Znf_RING/FYVE/PHD
IPR003126--Znf_UBR

PROSITE

PS51157--ZF_UBR

Pfam

PF02617--ClpS
PF02207--zf-UBR

SMART

SM00396--ZnF_UBR1

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0071596--P:ubiquitin-dependent protein catabolic process via the N-end rule pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001354	Ailuropoda melanoleuca	56.09	0.00e+00	1897.00
IUUC-Apl-004160	Anas platyrhynchos	57.83	0.00e+00	1959.00
IUUC-Aca-004982	Anolis carolinensis	55.53	0.00e+00	1895.00
IUUC-Ago-007752	Ashbya gossypii	25.04	4.00e-30	127.00
IUUC-Acl-008055	Aspergillus clavatus	25.12	6.00e-36	147.00
IUUC-Afl-008479	Aspergillus flavus	25.04	1.00e-31	133.00
IUUC-Afu-008929	Aspergillus fumigatus	24.92	4.00e-54	207.00
IUUC-Ani-009334	Aspergillus nidulans	27.17	5.00e-35	144.00
IUUC-Ang-009550	Aspergillus niger	24.49	3.00e-37	151.00
IUUC-Aor-010124	Aspergillus oryzae	25.04	1.00e-31	133.00
IUUC-Ate-010550	Aspergillus terreus	25.12	3.00e-36	148.00
IUUC-Ame-011231	Astyanax mexicanus	71.03	0.00e+00	2341.00
IUUC-Bta-012347	Bos taurus	57.03	0.00e+00	1908.00
IUUC-Bci-013834	Botrytis cinerea	25.12	2.00e-37	152.00
IUUC-Cja-018911	Callithrix jacchus	55.79	0.00e+00	1907.00
IUUC-Cfa-020991	Canis familiaris	56.86	0.00e+00	1931.00
IUUC-Cpo-021448	Cavia porcellus	56.03	0.00e+00	1913.00
IUUC-Csa-024255	Chlorocebus sabaeus	56.37	0.00e+00	1579.00
IUUC-Cho-024550	Choloepus hoffmanni	47.47	0.00e+00	932.00
IUUC-Dre-028643	Danio rerio	69.02	0.00e+00	1417.00
IUUC-Dno-029427	Dasypus novemcinctus	55.70	0.00e+00	1851.00
IUUC-Dor-031073	Dipodomys ordii	53.42	0.00e+00	816.00
IUUC-Ete-032318	Echinops telfairi	46.22	0.00e+00	731.00
IUUC-Eca-033348	Equus caballus	57.08	0.00e+00	1816.00
IUUC-Eeu-034664	Erinaceus europaeus	53.66	0.00e+00	1128.00
IUUC-Fca-035604	Felis catus	53.79	0.00e+00	1752.00
IUUC-Fal-037333	Ficedula albicollis	58.23	0.00e+00	1949.00
IUUC-Gmo-039363	Gadus morhua	71.19	0.00e+00	2133.00
IUUC-Ggr-040070	Gaeumannomyces graminis	25.23	5.00e-41	164.00
IUUC-Gga-040486	Gallus gallus	57.42	0.00e+00	1885.00
IUUC-Gac-041985	Gasterosteus aculeatus	79.11	0.00e+00	2440.00
IUUC-Hsa-046753	Homo sapiens	56.60	0.00e+00	1936.00
IUUC-Itr-048410	Ictidomys tridecemlineatus	56.77	0.00e+00	1912.00
IUUC-Lch-049904	Latimeria chalumnae	57.09	0.00e+00	1878.00
IUUC-Loc-052624	Lepisosteus oculatus	69.20	0.00e+00	2284.00
IUUC-Lma-053059	Leptosphaeria maculans	22.70	1.00e-44	176.00
IUUC-Laf-053857	Loxodonta africana	55.84	0.00e+00	1904.00
IUUC-Mcc-054873	Macaca mulatta	56.31	0.00e+00	1904.00
IUUC-Meu-056858	Macropus eugenii	46.79	0.00e+00	705.00
IUUC-Mor-057051	Magnaporthe oryzae	25.35	4.00e-37	151.00
IUUC-Mga-059917	Meleagris gallopavo	58.20	0.00e+00	1971.00
IUUC-Mmr-061128	Microcebus murinus	54.16	0.00e+00	1778.00
IUUC-Mdo-062306	Monodelphis domestica	57.34	0.00e+00	1911.00
IUUC-Mmu-063389	Mus musculus	57.13	0.00e+00	1944.00
IUUC-Mpu-065983	Mustela putorius furo	56.66	0.00e+00	1942.00
IUUC-Mlu-068013	Myotis lucifugus	55.56	0.00e+00	1855.00
IUUC-Nfi-068403	Neosartorya fischeri	24.18	3.00e-54	208.00
IUUC-Ncr-068864	Neurospora crassa	26.52	2.00e-25	112.00
IUUC-Nle-070031	Nomascus leucogenys	56.86	0.00e+00	1934.00
IUUC-Ont-072035	Oreochromis niloticus	79.66	0.00e+00	2737.00
IUUC-Ocu-074930	Oryctolagus cuniculus	54.84	0.00e+00	1863.00
IUUC-Oba-075295	Oryza barthii	46.43	4.00e-14	74.70
IUUC-Ogl-077571	Oryza glaberrima	41.83	2.00e-21	99.00
IUUC-Ogu-078497	Oryza glumaepatula	46.43	4.00e-14	74.70
IUUC-Oin-079343	Oryza indica	46.43	4.00e-14	74.70
IUUC-Oni-083099	Oryza nivara	46.43	5.00e-14	74.70
IUUC-Oru-084471	Oryza rufipogon	46.43	4.00e-14	74.70
IUUC-Osa-085336	Oryza sativa	43.88	3.00e-21	97.40
IUUC-Ola-086683	Oryzias latipes	76.91	0.00e+00	2602.00
IUUC-Oga-088017	Otolemur garnettii	54.54	0.00e+00	1831.00
IUUC-Oar-089557	Ovis aries	56.85	0.00e+00	1898.00
IUUC-Ptr-091366	Pan troglodytes	55.86	0.00e+00	1907.00
IUUC-Pan-092184	Papio anubis	56.31	0.00e+00	1903.00
IUUC-Psi-093720	Pelodiscus sinensis	56.75	0.00e+00	1877.00
IUUC-Pno-094877	Phaeosphaeria nodorum	33.88	2.00e-27	119.00
IUUC-Pfo-097124	Poecilia formosa	78.62	0.00e+00	2673.00
IUUC-Pab-098586	Pongo abelii	56.44	0.00e+00	1932.00
IUUC-Pop-099184	Populus trichocarpa	35.25	2.00e-11	63.50
IUUC-Pca-100673	Procavia capensis	51.31	0.00e+00	984.00
IUUC-Pva-102724	Pteropus vampyrus	53.08	0.00e+00	1727.00
IUUC-Pte-104174	Pyrenophora teres	22.60	4.00e-45	177.00
IUUC-Pyt-104431	Pyrenophora triticirepentis	22.81	2.00e-45	179.00
IUUC-Sha-106993	Sarcophilus harrisii	56.80	0.00e+00	1915.00
IUUC-Sja-107980	Schizosaccharomyces japonicus	23.76	1.00e-41	166.00
IUUC-Spo-108183	Schizosaccharomyces pombe	22.85	3.00e-45	178.00
IUUC-Sar-113447	Sorex araneus	55.25	0.00e+00	1295.00
IUUC-Sre-115045	Sporisorium reilianum	25.97	9.00e-45	176.00
IUUC-Ssc-115768	Sus scrofa	54.18	0.00e+00	1713.00
IUUC-Tgu-116949	Taeniopygia guttata	56.34	0.00e+00	1861.00
IUUC-Tsy-119177	Tarsius syrichta	52.58	0.00e+00	1088.00
IUUC-Tni-120884	Tetraodon nigroviridis	83.05	0.00e+00	2816.00
IUUC-Tme-127156	Tuber melanosporum	23.64	9.00e-48	186.00
IUUC-Tbe-128088	Tupaia belangeri	50.90	0.00e+00	712.00
IUUC-Uma-129344	Ustilago maydis	25.97	3.00e-49	191.00
IUUC-Vpa-130578	Vicugna pacos	51.72	0.00e+00	1673.00
IUUC-Xtr-132244	Xenopus tropicalis	50.51	0.00e+00	1643.00
IUUC-Xma-134112	Xiphophorus maculatus	78.40	0.00e+00	2689.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence