iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012496

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02052656

Gene Name

G2E3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000001617.5	ENSBTAT00000002121.5	ENSBTAP00000002121.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.50e-37	129.9	387	695

Active Site

Position(s)	Description	Evidence
665	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 7    krlevefvgEe...gldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlpl 92
           + +e+ +v+E+   g +++G+++efl+ll+++l+n++  lf  + + +++l+ n+++      +++l++ +G++++++l++g + + ++
   Q: 387  YTIEIVYVNENdhfGREQPGSKQEFLSLLMQQLENSS--LF--EGSLSKNLSLNSQAL-----KENLYYEAGKMVAISLVHGGPSPGFF 466
           578999999998899**********************..45..677788888888885.....689*********************** PP
   S: 93   sksfyklllgkklsledleevdpelyks.lkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvvey 180
           s++++++l   +   e+++ + +++ ++ + +i  + ++         t++  ++++ +++++    g+ +    +++k++  k+v+ y
   Q: 467  SQTLFNCLAYGP---ENTQPIVDDVSDFdVAQIMIRINTAA-------TVDDLNSLIHDYYKYLEFIGCLRLITSISDKYMLAKDVLVY 545
           ***********8...99999999999999888887743333.......3333445678899999999********************** PP
   S: 181  rlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevl.eefsseerkafLq.. 266
           ++ ++++  +e+f++G++++  le+++ + e  + +++++ e+++++ l++   ++ ++ +d +++  Fw+ + +++++ + +  ++  
   Q: 546  HVIKRVQAPFESFKQGLKTLGVLEKIQTYPEAFFHIFCHKPENLSAKILSD--LFTVHTLSDVQTL-GFWNSYlQAVEDGKSTVTMEdi 631
           *************************************************99..7888889999998.9998875777777766555455 PP
   S: 267  ..FvTgssrlPlgGfaelkprlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
             F+Tg++++P++Gf++ + ++ +++      ++P  n+C n+L LP  s++++++e + +Ai++t ++e
   Q: 632  liFATGCKSIPPAGFKPNP-SIECLHM-----DFPVGNKCDNCLALPITSTYKEFQESMDFAIKNTLRLE 695
           55**************977.999**99.....*********************************87665 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MNESKPGGSQ NSTCVFCRKN DDCPIKYGEK KTNEKWNLTV HYYCLLMSSG IWQRGKEEEG 60
VYGFLIEDIR KEVTRASKLK CSVCKKTGAS IGCVAPRCKR SYHFPCGLQR ECIFQFTGNF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGACACGACT GAGAAGCTAA TACAAGTACA CAAGTACAAG TAAGCTTAGA AAATAGCTGT 60
AAGAATAGTG AAAGGAACTC CTATATACCC TTTAAACAGA CTCCCCAGTG TATGTTTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR000569--HECT_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS50237--HECT
PS01359--ZF_PHD_1

Pfam

PF00632--HECT

SMART

SM00119--HECTc
SM00249--PHD

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding

KEGG

bta:508575

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001501	Ailuropoda melanoleuca	88.07	0.00e+00	1314.00
IUUC-Apl-003763	Anas platyrhynchos	58.74	0.00e+00	839.00
IUUC-Aca-004328	Anolis carolinensis	59.22	0.00e+00	852.00
IUUC-Ame-011288	Astyanax mexicanus	39.72	2.00e-158	552.00
IUUC-Cja-019756	Callithrix jacchus	85.65	0.00e+00	1280.00
IUUC-Cfa-020806	Canis familiaris	87.20	0.00e+00	1307.00
IUUC-Cpo-022519	Cavia porcellus	84.33	0.00e+00	1241.00
IUUC-Csa-023957	Chlorocebus sabaeus	86.65	0.00e+00	1293.00
IUUC-Cho-024375	Choloepus hoffmanni	79.13	0.00e+00	1127.00
IUUC-Cin-025325	Ciona intestinalis	41.72	6.00e-66	243.00
IUUC-Csv-026262	Ciona savignyi	42.66	4.00e-68	251.00
IUUC-Dre-027829	Danio rerio	39.94	7.00e-149	521.00
IUUC-Dno-029362	Dasypus novemcinctus	85.59	0.00e+00	1249.00
IUUC-Dor-030710	Dipodomys ordii	81.11	0.00e+00	1213.00
IUUC-Dse-031248	Dothistroma septosporum	38.46	1.80e-02	35.00
IUUC-Dme-031692	Drosophila melanogaster	35.47	8.00e-43	168.00
IUUC-Ete-032282	Echinops telfairi	76.24	0.00e+00	1091.00
IUUC-Eca-033963	Equus caballus	87.50	0.00e+00	1312.00
IUUC-Eeu-035029	Erinaceus europaeus	84.38	0.00e+00	1261.00
IUUC-Fca-036229	Felis catus	88.92	0.00e+00	1326.00
IUUC-Fal-037015	Ficedula albicollis	57.28	0.00e+00	857.00
IUUC-Gmo-039715	Gadus morhua	38.81	2.00e-76	279.00
IUUC-Gga-040298	Gallus gallus	57.47	0.00e+00	881.00
IUUC-Gac-041444	Gasterosteus aculeatus	39.38	8.00e-140	490.00
IUUC-Ggo-045456	Gorilla gorilla	86.51	0.00e+00	1285.00
IUUC-Hsa-046297	Homo sapiens	86.65	0.00e+00	1294.00
IUUC-Itr-047897	Ictidomys tridecemlineatus	84.80	0.00e+00	895.00
IUUC-Lch-050287	Latimeria chalumnae	66.14	2.00e-105	376.00
IUUC-Loc-052839	Lepisosteus oculatus	56.12	5.00e-31	125.00
IUUC-Laf-053581	Loxodonta africana	84.37	0.00e+00	1246.00
IUUC-Mcc-055615	Macaca mulatta	86.36	0.00e+00	1289.00
IUUC-Meu-056753	Macropus eugenii	47.25	1.00e-123	437.00
IUUC-Mga-059902	Meleagris gallopavo	57.34	0.00e+00	882.00
IUUC-Mmr-061522	Microcebus murinus	87.91	0.00e+00	1313.00
IUUC-Mdo-063022	Monodelphis domestica	63.17	0.00e+00	874.00
IUUC-Mmu-063609	Mus musculus	74.69	0.00e+00	1137.00
IUUC-Mpu-066656	Mustela putorius furo	87.36	0.00e+00	1312.00
IUUC-Mlu-067011	Myotis lucifugus	86.44	0.00e+00	1267.00
IUUC-Nle-069949	Nomascus leucogenys	86.36	0.00e+00	1288.00
IUUC-Opr-071224	Ochotona princeps	80.61	4.00e-127	448.00
IUUC-Ont-072174	Oreochromis niloticus	37.12	7.00e-135	474.00
IUUC-Oan-072712	Ornithorhynchus anatinus	66.04	0.00e+00	946.00
IUUC-Ocu-073776	Oryctolagus cuniculus	86.65	0.00e+00	1283.00
IUUC-Ola-087247	Oryzias latipes	37.94	5.00e-130	458.00
IUUC-Oga-088094	Otolemur garnettii	83.87	0.00e+00	1185.00
IUUC-Oar-090248	Ovis aries	96.44	0.00e+00	1413.00
IUUC-Ptr-090634	Pan troglodytes	86.79	0.00e+00	1291.00
IUUC-Pan-092876	Papio anubis	86.51	0.00e+00	1291.00
IUUC-Psi-093580	Pelodiscus sinensis	60.40	0.00e+00	868.00
IUUC-Pma-094295	Petromyzon marinus	53.01	2.00e-71	261.00
IUUC-Pfo-096351	Poecilia formosa	39.73	4.00e-147	515.00
IUUC-Pab-097596	Pongo abelii	86.79	0.00e+00	1293.00
IUUC-Pca-100309	Procavia capensis	77.38	0.00e+00	1146.00
IUUC-Pva-102526	Pteropus vampyrus	89.95	0.00e+00	830.00
IUUC-Rno-105432	Rattus norvegicus	78.98	0.00e+00	1186.00
IUUC-Sha-107089	Sarcophilus harrisii	64.11	0.00e+00	995.00
IUUC-Sar-113667	Sorex araneus	65.48	0.00e+00	934.00
IUUC-Ssc-116200	Sus scrofa	91.74	0.00e+00	1358.00
IUUC-Tgu-116467	Taeniopygia guttata	56.99	0.00e+00	840.00
IUUC-Tru-117690	Takifugu rubripes	38.86	6.00e-153	534.00
IUUC-Tsy-119481	Tarsius syrichta	84.00	0.00e+00	875.00
IUUC-Tni-119669	Tetraodon nigroviridis	36.97	4.00e-132	465.00
IUUC-Tbe-127241	Tupaia belangeri	77.95	0.00e+00	1121.00
IUUC-Ttr-129057	Tursiops truncatus	83.07	0.00e+00	1182.00
IUUC-Vpa-130685	Vicugna pacos	89.03	0.00e+00	1283.00
IUUC-Xtr-132555	Xenopus tropicalis	52.73	0.00e+00	741.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence